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71.Synthesis and in vitro and in vivo biological evaluation of novel derivatives of flexicaulin A as antiproliferative agents
71.Synthesis and in vitro and in vivo biological evaluation of novel derivatives of flexicaulin A as antiproliferative agents

As our research focuses on anticancer drugs, a series of novel derivatives of flexicaulin A (FA),...

2020-09-25
70.新型 2,4,6,-取代嘧啶衍生物的设计、合成和抗肿瘤活性研究
70.新型 2,4,6,-取代嘧啶衍生物的设计、合成和抗肿瘤活性研究

为了寻找高效的新型抗肿瘤药物,设计合成了一系列 2,4,6-取代嘧啶衍生物,并使用噻唑蓝(MTT)法对四种 ...

2020-09-25
69、RACO-1 modulates Hippo signalling in oesophageal squamous cell carcinoma
69、RACO-1 modulates Hippo signalling in oesophageal squamous cell carcinoma

Oesophageal cancer is one of the most lethal malignancies worldwide, whereas the 5-year survival ...

2020-09-23
68、OP16 induces deadly autophagy and apoptosis of cells by inhibiting Akt in esophageal squamous cell carcinoma
68、OP16 induces deadly autophagy and apoptosis of cells by inhibiting Akt in esophageal squamous cell carcinoma

OP16, a derivative of the novel ent-kaurene diterpenoid compound separated from Rabdosia rubescen...

2020-08-25
67、A low toxic CRM1 degrader: Synthesis and anti-proliferation on MGC803 and HGC27
67、A low toxic CRM1 degrader: Synthesis and anti-proliferation on MGC803 and HGC27

Chromosome region maintenance 1 (CRM1) is the sole nuclear exporter of several tumor suppressor, ...

2020-08-25
66、Regulation of Hippo/YAP signaling and Esophageal Squamous Carcinoma progression by an E3 ubiquitin ligase PARK2
66、Regulation of Hippo/YAP signaling and Esophageal Squamous Carcinoma progression by an E3 ubiquitin ligase PARK2

Esophageal squamous cell carcinoma (ESCC) is one of the most commonly diagnosed cancer types in C...

2020-08-06