姓    名

陈岚

职    称

副教授

研究方向

金属生物材料

邮    箱

chenlan@zzu.edu.cn

教育和科研工作经历：（时间倒序）

（1）2025-02 至 今，郑州大学，材料科学与工程学院，副教授

（2）2021-01 至 2025-01，郑州大学，材料科学与工程学院，讲师

（3）2015-09 至 2020-09，中国科学院大学，材料学，博士，导师：刘宣勇

（4）2011-09 至 2015-06，重庆大学，生物工程，学士

研究介绍： （200字以内,根据自身情况编辑）

围绕骨肿瘤和骨折等骨缺损和修复相关疾病，针对可降解生物镁合金降解速率过快的问题，研究兼具抗肿瘤和促成骨镁合金表面设计及其降解调控和相关作用机制的科学问题，开展微环境响应型镁合金表面复合涂层制备与相关生物学机制研究。与郑州大学第一附属医院、省肿瘤医院、中心医院等建立良好合作关系。获批国家自然科学基金青年项目、中国博士后科学基金面上项目、河南省科技研发联合基金项目、教育部产学合作协同育人项目等，参与国家自然科学基金面上项目、重点项目，申请国家发明专利4项，发表SCI论文数十篇。

荣誉与奖励：

1.《Rare Metals》期刊青年编委

2.《Exploartion》期刊青年编委

3．2025年河南省教育厅科技成果评定（科技论文类）二等奖,

4. 2025年中国材料大会邀请报告

5. 2024年中国生物材料大会邀请报告

代表性论著：（限10项内）

1. Lan Chen; Xi Wu; Dong Li; Shaosheng Jia; Jianan Yu; Bin Li; Jingan Li; Lingchuang Bai; Shaokang Guan ; Magnesium alloy implant with photothermal-enhanced ferroptosis towards a multimodal therapy strategy for osteosarcoma., Chemical Engineering Journal, 2025, 509 (期刊论文，第一作者)

2. Dong Li; Tong Zhang; Shaosheng Jia; Jianan Yu; Rongbang Sun; Liguo Wang; Lingchuang Bai; Lan Chen; Shaokang Guan; NIR/TME-responsive release of zoledronic acid-loaded LDHs on ZE21C magnesium alloy with multi-therapy for osteosarcoma, Journal of Magnesium and Alloys, 2026(期刊论文，共同通讯)

3. Yibing Zhu; Yufan Zang; Jianan Yu; Chengyu Li; Shaosheng Jia; Yuhan Liang; Lingchuang Bai; Bin Li; Jingan Li; Lan Chen; Montmorillonite-loaded magnesium alloy with photothermal and drug-enhanced anti-tumor and regulation of immune microenvironment for SVCS interventional

therapy, Rare Metals, 2025, 44(12): 10531-10557(期刊论文，共同通讯)

4. Jianan Yu; Shaosheng Jia; Rongbang Sun; Tong Zhang; Xinyuan Cai; Manli Song; Lan Chen; Han Lin; Shaokang Guan; MnOx-Armored Magnesium Implants for Anti-Osteosarcoma and Biofilm Eradication by Charge-Transfer Interference, Materials Today Bio, 2026, 37 (期刊论文，共同通讯作者 )

5. Jianan Yu; Shaosheng Jia; Rongbang Sun; Tong Zhang; Lingchuang Bai; Di Mei; Shijie Zhu; Lan Chen; Shaokang Guan; New Advances of Degradable Magnesium‐Based Metal Biomaterials in the Field of Orthopedics, Rare Metals, 2025, 45 (期刊论文，共同通讯作者)

6.Lan Chen; Donghui Wang; Jiajun Qiu; Xianming Zhang; Xingdan Liu; Yuqin Qiao; Xuanyong Liu; Synergistic effects of immunoregulation and osteoinduction of ds-block elements on titanium surface, Bioactive Materials, 2021, 6(1): 191-207  (期刊论文，第一作者)

7.  Lan Chen; Donghui Wang; Xingdan Liu; Bangcheng Yan; Haifeng Zhang; Xianming Zhang; Yuqin Qiao; Jiajun Qiu; Xuanyong Liu; Micro-galvanic effects of silver-containing titanium implants regulate the immune responses via activating voltage-gated calcium channels in macrophages, Chemical Engineering Journal, 2022, 428: 131068 (期刊论文，第一作者)

8. Lan Chen; Donghui Wang; Yu Zhang; Jiajun Qiu; Liping Ouyang; Yuqin Qiao; Xuanyong Liu; Nanostructural Surfaces with Different Elastic Moduli Regulate the Immune Response by Stretching Macrophages, Nano Letters, 2019, 19(6): 3480-3489 (期刊论文，第一作者)

9. Xinhui Zheng; Lan Chen; Ji Tan; Jianhua Miao; Xuanyong Liu; Tieyi Yang; Zhihong Ding; Effect of micro/nano-sheet array structures on the osteo-immunomodulation of macrophages, Regenerative Biomaterials, 2022, 9 (期刊论文，共同第一作者)

10. Xinyu Wang; Yuan Zhao; Yunwei Gu; Lingchuang Bai; Lan Chen; Shaokang Guan; Chondroitin sulfate and Cys-Ala-Gly peptides coated ZE21B magnesium alloy for enhanced corrosion resistance and vascular compatibility, International Journal of Biological Macromolecules, 2025, 311: 143895.  (期刊论文，共同通讯作者)