陈雪梅教授 博士 硕士生导师
1973年12月出生，博士，郑州大学基础医学院教授，硕士研究生导师。1998年毕业于河南医科大学获医学学士，留校任教，从事人体解剖学教学和神经解剖学科研工作，2003年毕业于郑州大学获医学硕士，2009年晋升为副教授，2021年晋升为教授。长期从事脑出血和脊髓损伤免疫机制及治疗和干细胞（胚胎干细胞和骨髓间充质干细胞）的研究。主要研究方向：主要从事脑卒中免疫机制及免疫治疗，干细胞，中枢神经系统损伤与修复等研究，解剖教学与脑健康科普等工作。主编或参编著作/教材11部，承担国家自然科学基金项目1项，承担河南省科技开放合作项目1项，参与国家级项目4项，主持省级科研课题6项，主持河南省科协科普中原院士讲坛新医科大健康项目1项，指导大学生创新性项目8项，其中国家级4项，发表教学和科研论文127篇，其中中文期刊69篇，SCI论文59篇。获省厅级科研成果一等奖1项，河南省高等教育省级教学成果一等奖 1项，河南省教育系统教学技能竞赛一等奖并荣获河南省教学标兵称号，授权国家发明专利2项，软件著作权专利1项。
在研课题
一、科研课题
(1) 2024年 河南省高端外国专家引进计划HNGD2024003 脑出血后运动障碍的神经振荡机制10万元 在研 主持
(2) 国家自然科学基金委员会, 面上项目 82371339 树突状细胞影响脑出血后淋巴细胞相关免疫炎性损伤的分子机制及关键调控靶点 2024-01-01 至 2027-12-31 49万元 在研 参与
二、教学课题
(1) 2024年度一流课程——正常人体形态功能学 校级 主持 在研
(2) 临床医学“5+3”一体化课程整合的内涵建设 校级 参加 在研
已结题课题
(1) 2021.01-2022.12 丰富环境通过Nrf2/BDNF/谷氨酰胺酶信号通路改善卒中后抑郁 科技攻关 212102310220 陈雪梅 项目负责人 10万
(2) 2022.01-2022.12中原科普讲坛（院士讲坛）——脑健康科普走社区进万家 河南省科协科普项目陈雪梅 项目负责人 6万
(3) 2018年01月01日-2020年12月31日 骨髓间充质干细胞源性外泌体移植缓解脊髓损伤后神经病理性痛的分子机制 U1704166 国家自然科学基金河南联合基金项目 陈雪梅 项目负责人 51万 国家自然科学基金委员会
(4) 2018.03-2019.02 干细胞来源的外泌体移植治疗脑出血：创新治疗途径及建立精准评估体系 182106000061 河南省科技开放合作计划项目 陈雪梅 项目负责人 30万 河南省科学技术厅
(5) 国家自然科学基金委员会，联合基金项目，U1604170，调控MSCs来源的外泌体对脊髓损伤后星形胶质细胞活化的作用，2017-01-01至2019-12-31，46万元，结题，参与
代表性SCI文章
(1) Qian Li, Abigail Weiland, Xuemei Chen, Xi Lan, Xiaoning Han, Frederick Durham, Xi Liu, Jieru Wan, Wendy C Ziai, Daniel F Hanley, Jian Wang. Corrigendum: Ultrastructural characteristics of neuronal death and white matter injury in mouse brain tissues after intracerebral hemorrhage: coexistence of ferroptosis, autophagy, and necrosis. Front Neurol.2024 Mar 1:15:1385719. doi:10.3389/fneur.2024.1385719. (IF=2.7).
(2) Rui Zhang, Ruoqi Ding, Qiao Wang, Linke Zhang, Xiaochong Fan, Fuyou Guo, Xuemei Chen, Chao Jiang, Jing Cao, Junmin Wang, Weidong Zang, Jian Wang. Inflammation in intracerebral hemorrhage: A bibliometric perspective. Brain Hemorrhages. Volume 5, Issue 3, 2024 June;5(3):107-116.dio: 10.1016/j.hest.2024.01.003.(IF=1.3)
(3) Yunfan Yang, Zixiang Li, Xiaochong Fan, Chao Jiang, Junmin Wang, Yousef Rastegar-Kashkooli, Tom J. Wang, Junyang Wang, Menglu Wang, Nannan Cheng, Xiqian Yuan, Xuemei Chen*(共同通讯), Bing Jiang*, and Jian Wang*.Nanozymes: Potential Therapies for Reactive Oxygen Species Overproduction and Inflammation in Ischemic Stroke and Traumatic Brain Injury. ACS Nano.2024 Jul 2;18(26):16450-16467. doi: 10.1021/acsnano.4c03425.(IF=15.8).
(4) Luwei Nie, Jinxin He, Junmin Wang, Ruike Wang, Leo Huang, Lin Jia, Yun Tai Kim, Ujjal K Bhawal, Xiaochong Fan, Marietta Zille, Chao Jiang, Xuemei Chen*(共同通讯), Jian Wang*.Environmental Enrichment for Stroke and Traumatic Brain Injury: Mechanisms and Translational Implications. Comprehensive Physiology.2023 Dec 29;14(1):5291-5323.doi: 10.1002/cphy.c230007.(IF=4.2).
(5) Shiqiang Zhang, Jiannan Wang, Jingjing Zhang, Gaolei Xu, Zhenhua Zhang, Yongkui Wang, Cheng Chang, Xuemei Chen, Ming Li, Jing Cao, Weidong Zang.The impact of enhancing publicity and commemoration of body donors at Zhengzhou University, China.Anat Sci Educ.2023 May-Jun;16(3):405-414. doi:10.1002/ase.2259.(IF=5.2).
(6) Shaoshuai Wang, Xiuhua Ren, Junmin, Qinfeng Peng, Xiaoyu Niu, Chunhua Song, Changsheng Li, Chao Jiang, Weidong Zang, Marietta Zille, Xiaochong Fan*, Xuemei Chen*(共同通讯), Jian Wang*.Blocking autofluorescence in brain tissues affected by ischemic stroke, hemorrhagic stroke, or traumatic brain injury. Front Immunol. 2023 May 29:14:1168292. doi: 10.3389/fimmu.2023.1168292.(IF=5.7)
(7) Limin Wang, Zhihua Liu, Honglei Ren, Xuemei Chen, Junmin Wang, Huimin Cai, Liping Wei, Huihong Tian, Jian Wang, Lijuan Wang. A novel aged mouse model of recurrent intracerebral hemorrhage in the bilateral striatum. Neural Regen Res. 2023 Feb;18(2):344-349. doi: 10.4103/1673-5374.346459. (IF=6.058).
(8) Yinrou Huang, Mengke Zhao, Xuemei Chen, Ruoyu Zhang, Anh Le, Michael Hong, Yufei Zhang, Lin Jia, Weidong Zang, Chao Jiang, Junmin Wang, Xiaochong Fan, Jian Wang.Tryptophan metabolism in diseases of the central nervous system: pathophysiology and potential therapeutic strategies.Aging Dis.2023 Jun 1;14(3):858-878.doi: 10.14336/AD.2022.0916.(IF=7.0).
(9) Peijun Jia, Junmin Wang, Xiuhua Ren, Jinxin He,Shaoshuai Wang, Yinpei Xing, Danyang Chen,Xinling Zhang, Siqi Zhou, Xi Liu, Shangchen Yu, Zefu Li,Chao Jiang, Weidong Zang, Xuemei Chen*(共同通讯) and Jian Wang*An enriched environment improves long-term functional outcomes in mice after intracerebral hemorrhage by mechanisms that involve the Nrf2/BDNF/glutaminase pathway. ournal of Cerebral Blood Flow &Metabolism,2022, DOI: 10.1177/0271678X221135419.
(10) Ruoyu Zhang, Chen Sun, Yunze Han, Leo Huang, Honghui Sheng, Jing Wang, Yuqing Zhang, Jonathan Lai, Jiahao Yuan, Xuemei Chen, Chao Jiang, Fuyuan Wu, Junmin Wang, Xiaochong Fan, Jian Wang. Neutrophil autophagy and NETosis in COVID-19: perspectives. Autophagy. 2022,11:1-10. doi:10.1080/15548627.2022.2099206. (IF=13.391)
(11) Chen Sun, Yunze Han, Ruoyu Zhang, Simon Liu, Jing Wang, Yuqing Zhang, Xuemei Chen, Chao Jiang, Junmin Wang, Xiaochong Fan, Jian Wang. Regulated necrosis in COVID-19: A double-edged sword. Front Immunol. 2022 Aug 25;13:917141. doi: 10.3389/fimmu.2022.917141. (IF=8.786)
(12) Zefu Li, Huiying Bai, Ruoyu Zhang, Bohan Chen, Junmin Wang, Bohan Xue, Xiuhua Ren, Jiarui Wang, Yanjie Jia, Weidong Zang, Jian Wang, Xuemei Chen*, Systematic analysis of critical genes and pathways identified a signature of neuropathic pain after spinal cord injury. Eur J Neurosci. 2022 Jul;56(2):3991-4008. doi: 10.1111/ejn.15693. (IF=3.698)
(13) Li Zhu, Leo Huang, Anh Le, Tom J. Wang, Jiewen Zhang, Xuemei Chen, Junmin Wang, Jian Wang, Chao Jiang, Interactions between the Autonomic Nervous System and the Immune System after Stroke. Compr Physiol. 2022 Jun 29;12(3):3665-3704. doi: 10.1002/cphy.c210047. (IF=8.915)
(14) Ruoyu Zhang, Chen Sun, Xuemei Chen, Yunze Han, Weidong Zang, Chao Jiang, Junmin Wang, Jian Wang. COVID-19-Related Brain Injury: The Potential Role of Ferroptosis. J Inflamm Res. 2022 Apr 5;15:2181-2198. doi: 10.2147/JIR.S353467. (IF=4.631)
(15) Chengli Liu, Jie Xie, Shanshan Sun, Hui Li, Tianyu Li, Chao Jiang, Xuemei Chen, Junmin Wang, Anh Le, Jiarui Wang, Zhanfei Li, Jian Wang, Wei Wang. Hemorrhagic Transformation After Tissue Plasminogen Activator Treatment in Acute Ischemic Stroke. Cell Mol Neurobiol. 2022 Apr;42(3):621-646. doi: 10.1007/s10571-020-00985-1. Epub 2020 Oct 30. (IF=4.231)
(16) Lin Shang, Tao Peng, Xuemei Chen, Zhiyong Yan, Junmin Wang, Xiaoqun Gao, Cheng Chang. miR-590-5p Overexpression Alleviates β-Amyloid-Induced Neuron Damage via Targeting Pellino-1. Anal Cell Pathol (Amst). 2022 Mar 8;2022:7657995. doi: 10.1155/2022/7657995. (IF=4.133)
(17) Wei Zhu, Yufeng Gao, Jieru Wan, Xi Lan, Xiaoning Han, Shanshan Zhu, Weidong Zang, Xuemei Chen, Wendy Ziai, Daniel F Hanley, Scott J Russo, Ricardo E Jorge, Jian Wang. Changes in motor function, cognition, and emotion-related behavior after right hemispheric intracerebral hemorrhage in various brain regions of mouse. Brain Behav Immun. 2018 Mar;69:568-581. doi: 10.1016/j.bbi.2018.02.004. (IF=19.277).
(18) Pian Gong, Zhan Zhang, Changlin Zou, Qi Tian, Xuemei Chen, Michael Hong, Xi Liu, Qianxue Chen, Zhou Xu, Mingchang Li, Jian Wang. Corrigendum to "Hippo/YAP signaling pathway mitigates blood-brain barrier disruption after cerebral ischemia/reperfusion injury" [Behav. Brain Res. 356 (2019) 8-17]. Behav Brain Res. 2022 Jan 7;416:113531. doi: 10.1016/j.bbr.2021.113531. (IF=3.352)
(19) Ruoyu Zhang, Junming Wang, Leo Huang, Tom J Wang, Yinrou Huang, Zefu Li, Jinxin He, Chen Sun, Jing Wang, Xuemei Chen*(共同通讯), Jian Wang*, The pros and cons of motor, memory, and emotion-related behavioral tests in the mouse traumatic brain injury model. Neurol Res. 2022 Jan;44(1):65-89. doi: 10.1080/01616412.2021.1956290. (IF=2.529)
(20) Peijun Jia, Jinxin He, Zefu Li, Junmin Wang, Lin Jia, Ruochen Hao, Jonathan Lai, Weidong Zang, Xuemei Chen*(共同通讯), Jian Wang*. Profiling of Blood-Brain Barrier Disruption in Mouse Intracerebral Hemorrhage Models: Collagenase Injection vs. Autologous Arterial Whole Blood Infusion. Front Cell Neurosci. 2021 Aug 26;15:699736. doi: 10.3389/fncel.2021.699736. (IF=6.147)
(21) Fang Wang, Xuemei Chen, Bo Sun, Yujia Ma, Wenbin Niu, Jun Zhai, Yingpu Sun*, Hypermethylation-mediated downregulation of lncRNA PVT1 promotes granulosa cell apoptosis in premature ovarian insufficiency via interacting with Foxo3a. J Cell Physiol. 2021 Jul;236(7):5162-5175. doi:10.1002/jcp.30222. (IF=6.513)
(22) Xiaoyu Shi, Huiying Bai, Junmin Wang, Jiarui Wang, Leo Huang, Meimei He, Xuejun Zheng, Zitian Duan, Danyang Chen, Jiaxin Zhang, Xuemei Chen*(共同通讯), Jian Wang*, Behavioral Assessment of Sensory, Motor, Emotion, and Cognition in Rodent Models of Intracerebral Hemorrhage. Front Neurol. 2021 Jun 17;12(667511) (IF=4.086)
(23) Delong Qin, Junmin Wang, Anh Le, Tom J. Wang, Xuemei Chen, Jian Wang*，Traumatic Brain Injury: Ultrastructural Features in Neuronal Ferroptosis, Glial Cell Activation and Polarization, and Blood-Brain Barrier Breakdown. Cells. 2021 Apr 24;10(5):1009. doi: 10.3390/cells10051009. (IF=7.666)
(24) Ye Zhang, Dan Zhao; Xutong Li, Beiyao Gao, Chengcheng Sun, Shaoting Zhou, Yanhong Ma*, Xuemei Chen*(共同通讯), Dongsheng Xu*, The Wnt/β-Catenin Pathway Regulated Cytokines for Pathological Neuropathic Pain in Chronic Compression of Dorsal Root Ganglion Model. Neural Plast. 2021 Apr 19;2021:6680192. (IF=3.144)
(25) Danyang Chen, Junmin Wang, Yinpei Xing, Peijun Jia, Yuheng Zhang, Jiarui Wang, Honglei Ren, Anh Le , Xuemei Chen*(共同通讯), Jian Wang*，Behavioral assessment of post-stroke depression and anxiety in rodents. Brain Hemorrhages.2020.
(26) Honglei Ren, Ranran Han, Xuemei Chen, Xi Liu, Jieru Wan, Limin Wang, Xiuli Yang, Jian Wang. Potential therapeutic targets for intracerebral hemorrhage-associated inflammation: An update. J Cereb Blood Flow Metab. 2020 Sep;40(9):1752-1768. doi: 10.1177/0271678X20923551. (IF=6.960)
(27) Wei Hua*, Xuemei Chen*(共同第一) , Junmin Wang , Weidong Zang , Chao Jiang, Honglei Ren , Michael Hong , Jiarui Wang , He Wu , Jian Wang , Mechanisms and potential therapeutic targets for spontaneous intracerebral hemorrhage. Brain Hemorrhages.2020.
(28) Tianwu Zhang,*, Junmin Wang,*, Wenbin Niu, Fang Wang, Jin Liu,Yinpei Xing, Peijun Jia, Xiuhua Ren, Jiarui Wang, Weidong Zang and Xuemei Chen*(通讯), Bioinformatic prediction of the structure and characteristics of human sperm acrosome membrane-associated protein 1 (hSAMP32) and evaluation of its antifertility function in vivo, Reproduction , Fertility and Development.2020.(IF=1.718)
(29) Chengli Liu, Changsheng Huang, Jie Xie,1 Hui Li, Michael Hong, Xuemei Chen, Junmin Wang, Jiarui Wang, Zhanfei Li, Jian Wang*, Wei Wang*, Potential Efficacy of Erythropoietin on Reducing the Risk of Mortality in Patients with Traumatic Brain Injury: A Systematic Review and Meta-Analysis. BioMed Research International.2020. (IF=3.246).
(30) Xuemei Chen, Yuping Li, Chenfeng Hua, Peijun Jia, Yinpei Xing, Bohan xue, Xiaoyi Tian,Yuanyuan Yang, Junxia Zhang, Liangjun Qiao, Huimin Liu, Xiang Li*, Fuwei Xie*, Establishment of rapid risk assessment model for cigarette smoke extractexposure in chronic obstructive pulmonary disease. Toxicology Letters 316 (2019) 10–19 (IF=4.271)
(31) Zou Changlin, Tian Qi, Liu Xi, Xu Zhou, Gong Pian, Zhang Zhan, Li Mingchang*, Chen Xuemei, Wang Jian*, Chen Qianxue, Hong. Hippo/YAP signaling pathway mitigates blood-brain barrier disruption after cerebral ischemia/reperfusion injury. Behavioural Brain Research: An International Journal,2019,356:8-17. (IF=3.352)
(32) Han Xiaoning, Zhao Xiaochun, Lan Xi, Li Qian, Gao Yufeng, Liu Xi, Wan Jieru, Yang Zengjin, Chen Xuemei, Zang Weidong, Guo Austin M, Falck John R, Koehler Raymond C, Wang Jian*. 20-HETE synthesis inhibition promotes cerebral protection after intracerebral hemorrhage without inhibiting angiogenesis. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism,2019,39(8) (IF=6.960)
(33) Zhu Huimin, Wang Zhiqiang, Yu Jixu, Yang Xiuli, He Feng, Liu Zhenchuan*, Che Fengyuan*, Chen Xuemei, Ren Honglei, Hong Michael, Wang Jian*. Role and Mechanisms of Cytokines in the Secondary Brain Injury After Intracerebral Hemorrhage. Progress in neurobiology,2019. (IF=10.885)
(34) 王君敏,李鸣,尚琳,杨雪晴,陈雪梅*(通讯作者).医科大学生科研创新的必要性与培养策略[J].教育现代化,2019,6(85):65-68.
(35) Weihua Cai, Qingzan Zhao, Jinping Shao, Jingjing Zhang, Lei Li, Xiuhua Ren, Songxue Su, Qian Bai, Ming Li, Xuemei Chen, Jian Wang, Jing Cao, Weidong Zang. MicroRNA-182 Alleviates Neuropathic Pain by Regulating Nav1.7 Following Spared Nerve Injury in Rats. Sci Rep. 2018 Nov 13;8(1):16750. doi: 10.1038/s41598-018-34755-3. (IF=4.996)
(36) Lin Wang, Shuang Pei, Linlin Han, Bin Guo, Yanfei Li, Ranran Duan, Yaobing Yao, Bohan Xue, Xuemei Chen, Yanjie Jia. Mesenchymal Stem Cell-Derived Exosomes Reduce A1 Astrocytes via Downregulation of Phosphorylated NFκB P65 Subunit in Spinal Cord Injury. Cell Physiol Biochem. 2018;50(4):1535-1559. doi: 10.1159/000494652.
(37) Xiangsheng Zhang, Qi Wu, Yue Lu, Jieru Wan, Haibin Dai, Xiaoming Zhou, Shengyin Lv, Xuemei Chen, Xin Zhang, Chunhua Hang, Jian Wang. Cerebroprotection by salvianolic acid B after experimental subarachnoid hemorrhage occurs via Nrf2- and SIRT1-dependent pathways. Free Radic Biol Med. 2018 Aug 20;124:504-516. doi: 10.1016/j.freeradbiomed.2018.06.035. (IF=8.101)
(38) Wanliang Dong, Yuankun Zhang, Xuemei Chen, Yanjie Jia. High-Dose Tanshinone IIA Suppresses Migration and Proliferation While Promoting Apoptosis of Astrocytoma Cells Via Notch-1 Pathway. Neurochem Res. 2018 Sep;43(9):1855-1861. doi: 10.1007/s11064-018-2601-0. (IF=4.414)
(39) Qian Li, Abigail Weiland, Xuemei Chen, Xi Lan, Xiaoning Han, Frederick Durham, Xi Liu, Jieru Wan, Wendy C Ziai, Daniel F Hanley, Jian Wang. Ultrastructural Characteristics of Neuronal Death and White Matter Injury in Mouse Brain Tissues After Intracerebral Hemorrhage: Coexistence of Ferroptosis, Autophagy, and Necrosis. Front Neurol. 2018 Jul 17;9:581. doi: 10.3389/fneur.2018.00581. (IF=4.086)
(40) Jianping, Wang, Di Zhang, Xiaojie Fu, Lie Yu, Zhengfang Lu, Yufeng Gao, Xianliang Liu, Jiang Man, Sijia Li, Nan Li, Xuemei Chen, Michael Hong, Qingwu Yang, Jian Wang. Carbon monoxide-releasing molecule-3 protects against ischemic stroke by suppressing neuroinflammation and alleviating blood-brain barrier disruption. J Neuroinflammation. 2018 Jun 21;15(1):188. doi: 10.1186/s12974-018-1226-1. (IF=9.587)
(41) Wang Junmin*, Jiang Chao, Zhang Kun, Lan Xi, Chen Xuemei, Zang Weidong, Wang Zhongyu, Guan Fangxia, Zhu Changlian, Yang Xiuli, Lu Hong*, Wang Jian*, Melatonin receptor activation provides cerebral protection after traumatic brain injury by mitigating oxidative stress and inflammation via the Nrf2 signaling pathway.[J]. Free radical biology & medicine,2018,131(IF=8.101)
(42) Xuemei Chen*(共同通讯), Bohan Xue, Yuping Li, Chunhua Song, Peijun Jia, Xiuhua Ren Weidong Zang*, Jian Wang, Meta-Analysis of stem cell transplantation for reflex hypersensitivity after spinal cord injury. Neuroscience.2017, 363:66-75 (IF=3.708)
(43) Jianping Wang, Xiaojie Fu, Di Zhang, Lie Yu, Zhengfang Lu, Yufeng Gao, Xianliang Liu, Jiang Man, Sijia Li, Nan Li, Menghan Wang, Xi Liu, Xuemei Chen, Weidong Zang, Qingwu Yang, Jian Wang. Effects of crenolanib, a nonselective inhibitor of PDGFR, in a mouse model of transient middle cerebral artery occlusion. Neuroscience. 2017 Nov 19;364:202-211. doi: 10.1016/j.neuroscience.2017.09.025. (IF=3.708)
(44) Jianping Wang, Zhengfang Lu, Xiaojie Fu, Di Zhang, Lie Yu, Nan Li, Yufeng Gao, Xianliang Liu, Chunmao Yin, Junji Ke, Liyuan Li, Mengmeng Zhai, Shiwen Wu, Jiahong Fan, Liang Lv, Junchao Liu, Xuemei Chen, Qingwu Yang, Jian Wang. Alpha-7 Nicotinic Receptor Signaling Pathway Participates in the Neurogenesis Induced by ChAT-Positive Neurons in the Subventricular Zone. Transl Stroke Res. 2017 May 27:10.1007/s12975-017-0541-7. doi: 10.1007/s12975-017-0541-7. (IF=6.800)
(45) Li Z,Chen X, Zhang X, Ren X, Chen X, Cao J, Zang W*, Liu X, Guo F. Small Interfering RNA Targeting Dickkopf-1 Contributes to Neuroprotection After Intracerebral Hemorrhage in Rats. J Mol Neurosci. 2017, 61(2):279-288(IF=8.5565)
(46) Weihua Cai, Jing Cao, Xiuhua Ren, Liang Qiao, Xuemei Chen, Ming Li, Weidong Zang. shRNA mediated knockdown of Nav1.7 in rat dorsal root ganglion attenuates pain following burn injury. BMC Anesthesiol. 2016 Aug 11;16(1):59. doi: 10.1186/s12871-016-0215-0. (IF=2.376)
(47) Chen X*, Liu X, Ren X, Li X, Wang L, Zang W*, Discovery of human posterior head 20 (hPH20) and homo sapiens sperm acrosome associated 1 (hSPACA1) immunocontraceptive epitopes and their effects on fertility in male and female mice, Reprod Fertil Dev, 2016, 28(4) : 416-27 ( IF =2.4)
(48) Chen Xuemei*, Niu Wenbin, Wang Fang, Yu Wenzhu, Dai Shanjun, Kong Huijuan, Shu Yimin, Sun Yingpu *, Derivation of Normal Diploid Human Embryonic Stem Cells From Tripronuclear Zygotes With Analysis of Their Copy Number Variation and Loss of Heterozygosity,Molecular Reproduction and Development, 2015, 82(5) : 344-355. (IF =2.141)
(49) Yu Wenzhu*, Chen Xuemei*, Niu Wenbin, Wang Fang, Sun Yingpu*, Role of Wnt5a in the differentiation of human embryonic stem cells into endometrium-like cells, International Journal of Clinical and Experimental Pathology, 2015 , 8(5) : 5478-5484 .(IF= 2.125)
(50) Chen Xuemei *, Kan Quancheng, Wang Fang, Kong Huijuan, Zhang Weihong, Yu Wenzhu, Sun Yingpu*, Chromosome Dynamic Changes in Two cultured chinese human embryonic stem cell lines: Single nucleotide polymorphism, copy number variation and loss of heterozygosity, Journal of Cellular Biochemistry, 2012, 113(11) : 3520-3527.(IF= 3.062)
(51) Pengfen Li, Fang Wang, Huijuan Kong, Fang Zhao, Aihong Bai, Xuemei Chen, Yingpu Sun. Establishment of polycystic ovary syndrome-derived human embryonic stem cell lines. Gynecol Endocrinol. 2012 Jan;28(1):25-8. doi: 10.3109/09513590.2011.588748. (IF=2.277).
(52) Yu Wenzhu*, Niu Wenbin, Wang Shuna, Chen Xuemei, Sun Bo, Wang，Fang, Sun Yingpu *, Co-culture with endometrial stromal cells enhances the differentiation of human embryonic stem cells into endometrium-like cells，Experimental and Therapeutic Medicine, 2015, 10(1) : 43-50 (IF=1.28)
(53) Wang Fang*, Liu Weiwei, Chen Xuemei, Kong Huijuan, Li Jing,Sun Yingpu*,Differential genes in adipocytes induced from polycystic and non-polycystic ovary syndrome-derived human embryonic stem cells, Systems Biology in Reproductive Medicine, 2014, 60(3) : 136-142 (IF= 1.6)
(54) Song Wenyan*, Xin Zhimin, Jin Haixia, Peng Zhaofeng, Chen Xuemei, Shi Senlin, Dai Shanjun, Sun Yingpu*, Effects of frozen timing on the spindle density, the angle between the polar body and spindle, and embryo development of intracytoplasmic sperm injection in mouse mature oocytes, Cell Biology International 2013, 37(6) : 561-567 (IF =1.635)
(55) Li Pengfen*, Wang Fang, Kong Huijuan, Zhao Fang, Bai, Chen Xuemei, Sun Yingpu *, Establishment of polycystic ovary Ai-hong,syndrome-derived human embryonic stem cell lines, Gynecological Endocrinology, 2012, 28(1) : 25-28 (IF= 1.303)
