王婷,副教授,硕士生导师,河南省青年骨干教师。近年来主要从事免疫调控机制领域的研究工作,聚焦肿瘤发生相关免疫抑制和疾病相关免疫稳态失调等研究方向。主持国家自然科学基金项目1项、河南省高等学校重点科研项目计划1项,并作为主要人员参与国家自然科学基金联合重点项目、重大研究计划培育项目、科技部“十二五”“重大新药创制”科技重大专项等重要科研项目。在J Biol Chem、Cancer Letter等生物医学领域重要期刊发表SCI论文10余篇,参编“十二五本科教学工程”教材1部,获授权国家发明专利2项,获河南省科学技术进步奖二等奖1项。
教育经历:
2002.09–2007.07,兰州大学,生物化学与分子生物学专业,理学博士
1998.09–2002.07,兰州大学, 生物化学专业,理学学士
科研与学术工作经历:
2018.03–至今,郑州大学,生命科学学院,副教授
2013.03–2018.03,郑州大学,生命科学学院,讲师
2008.12–2013.03,美国纽约血液中心,国家脐带血项目,高级技术专员
2008.03–2008.12,美国纽约血液中心,博士后
2007.07–2008.03,郑州大学,生命科学学院,讲师
近期发表论文:
1. Chengbo Wang, Keyan Li, Yingli Men, Cong Ding, Juan Du, Taotao Liang, Zhenyu Ji, Lixiang Chen, Ting Wang*, Qiaozhen Kang*. Protein 4.1B Suppresses Tumor Metastasis by Regulating Epithelial-mesenchymal Transition Progression in Melanoma Cells. Int J Med Sci. 2019. 16(4):529-536.
2. Lixiang Chen#, Ting Wang#, Xiang Ji, Cong Ding, Taotao Liang, Xin Liu, Jike Lu, Xinrui Guo, Qiaozhen Kang, Zhenyu Ji. Cytoskeleton protein 4.1R suppresses murine keratinocyte cell hyperproliferation via activating the Akt/ERK pathway in an EGFR-dependent manner. Exp Cell Res. 2019, 384(2):111648.
3. Ting Wang, Mingxuan Du, Zhenyu Ji, Cong Ding, Chengbo Wang, Yingli Men, Shimeng Liu, Taotao Liang, Xin Liu, Qiaozhen Kang. Recombinant protein rMBP-NAP restricts tumor progression by triggering antitumor immunity in mouse metastatic lung cancer , Can J Physiol Pharmacol. 2018. 96(2):113-119.
4. Ting Wang#, Siwei Chen#, Shihui Wang, Liang Shi, Chenggong Wang, Jingxin Zhang, Yanfeng Gao, Guodong Li, Yuanming Qi, Xiuli An, Lixiang Chen. Targeting neurokinin-3 receptor: a novel anti-angiogenesis strategy for cancer treatment. Oncotarget. 2017,8(25):40713-40723.
5. Lixiang Chen#, Ting Wang#, Yaomei Wang, Jingxin Zhang, Yuanming Qi, Haibo Weng, Qiaozhen Kang, Xinhua Guo, Anthony J. Baines, Narla Mohandas, Xiuli An. Protein 4.1G Regulates Cell Adhesion, Spreading and Migration of Mouse Embryo Fibroblasts through β1 Integrin Pathway. The Journal of Biological Chemistry. (2016) 291(5): 2170-2180.
6. Xin Liu, Guo Fu, ZhenyuJi, Xiabing Huang, Cong Ding, Hui Jiang, Xiaolong Wang, Mingxuan Du, Ting Wang*, Qiaozhen Kang*, A recombinant DNA Plasmid encoding the sIL-4R-NAP fusion protein suppress airway inflammation in an OVA-induced mouse model of asthma, Inflammation, 2016
7. Ting Wang, Xilong Liu, ZhenyuJi, Yingli Men, Mingxuan Du, CongDing, Yahong Wu, Xin Liu*, Qiaozhen Kang*, Antitumor and immunomodulatory effects of recombinant fusion protein rMBP-NAP through TLR-2 dependent mechanism in tumor-bearing mice, International Immunopharmacology, 2015, 29(2): 876-883.
8. XinLiu, Qingqing Zhou, ZhenyuJi, Guo Fu, Yi Li, Xiaobei Zhang, Xiaofang Shi, Ting Wang*, Qiaozhen Kang*, Protein 4.1R attenuatesautoreactivity in experimental autoimmune encephalomyelitis by suppressing CD4 +T cell activation, Cellular Immunology, 2014, 292: 19-24.
9. Ting Wang, Li-Xiang Chen, Yuan Long, Wei-Min Wua, Rui Wang. DNA damage induced by caffeic acid phenyl ester in the presence of Cu(II) ions: potential mechanism of its anticancer properties. Cancer Letters. (2008) 263(1): 77-88.
近期获授权专利:
1. FAP来源的抗肿瘤CTL表位肽P265及其应用。专利号:ZL201610361347.8
2. sIL-4R-NAP融合基因。专利号:ZL201410161397.2
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