郑州大学 医学科学院 欢迎您!

师资队伍

司玲玲

作者:   时间:2024年03月20日 12:00   点击数:

        职称:讲师

        电话0371-68063887

        邮箱silingling@zzu.edu.cn

        地址:郑州大学二七区大学北路40号博士后楼504室







个人简介

2014年在石河子大学药学专业获理学学士学位;2017年在石河子大学药理学专业获理学硕士学位;2020年在沈阳药科大学药理学专业获理学博士学位;2020年8月被聘为郑州大学医学科学院讲师;2021年获得河南省博士后基金的资助;2022年获得河南省科技攻关项目的资助;2023年获得国家青年科学基金项目的资助。



主要研究方向

主要从事CAR-T免疫治疗、天然药物抗肿瘤治疗过程中线粒体相关机制的探究。

 

 

代表性成果

(1) Lingling Si; Jianing Fu; Weiwei Liu; Toshihiko Hayashi; Kazunori Mizuno; Shunji Hattori; Hitomi Fujisaki; Satoshi Onodera; Takashi Ikejima ; Silibinin-induced mitochondria fission leads to mitophagy, which attenuates silibinin-induced apoptosis in MCF-7 and MDA-MB-231 cells, Archives of Biochemistry and Biophysics, 2020, 685: 108284-108323.

(2) Lingling Si; Weiwei Liu; Toshihiko Hayashi; Yachao Ji; Jianing Fu; Yuheng Nie; Kazunori Mizuno; Shunji Hattori; Satoshi Onodera; Takashi Ikejima ; Silibinin-induced apoptosis of breast cancer cells involves mitochondrial impairment, Archives of Biochemistry and Biophysics, 2019,671: 0003-9861.

(3) Lingling Si; Jianing Fu; Weiwei Liu; Toshihiko Hayashi; Yuheng Nie; Kazunori Mizuno; Shunji Hattori; Hitomi Fujisaki; Satoshi Onodera; Takashi Ikejima ; Silibinin inhibits migration and invasion of breast cancer MDA-MB-231 cells through induction of mitochondrial fusion, Molecular and Cellular Biochemistry, 2019, 463: 186-201.

(4) Yuanyuan Zhao; Louisa S Chard Dunmall; Zhenguo Cheng; Yaohe Wang; Lingling Si; Natural products targeting glycolysis in cancer, Frontiers in Pharmacology, 2022, 13.

(5) Lingling Si; Xinyan Yan; Yan Wang; Boxue Ren; Huanhuan Ren; Yangfang Ding; Qiusheng Zheng; Defang Li; Ying Liu ; Chamaejasmin B Decreases Malignant Characteristics of Mouse Melanoma B16F0 and B16F10 Cells, Frontiers in Oncology, 2020, 10: 415.

(6) Lingling Si, Xinyan Yan, Wenjin Hao, Xiaoyi Ma, Huanhuan Ren, Boxue Ren, Defang Li, Zhengping Dong, Qiusheng Zheng. Licochalcone D induces apoptosis and inhibits migration and invasion in human melanoma A375 cells. Oncology Reports. 2018 May;39(5):2160-2170.

(7) Lingling Si, Xinhui Yang, Xinyan Yan, Yanming Wang, Qiusheng Zheng. Isoliquiritigenin induces apoptosis of human bladder cancer T24 cells via a cyclin-dependent kinase-independent mechanism. Oncology Letters. 2017 Jul;14(1):241-249.

[8] 司玲玲,马俊,任欢欢,等. 刺槐素对乳腺癌T47D细胞增殖的影响[J].中国药理学通报, 2017, 33(02):260-267.

 

 

上一篇: 谢力行
下一篇: 王琳

地址:郑州市二七区大学北路40号  邮编:450052   电话:0371-66658832   传真:0371-66658832  

邮箱: HR-ZZUAMS@zzu.edu.cn    Dean-ZZUAMS@zzu.edu.cn

Copyright @2019 郑州大学医学科学院 All Right Reserved.