计算生物学  应用微分方程模型揭示生命体时间和空间动态发展的分子机制，主要包括神经退行性疾病发病机制、机体组织应答环境机制、细胞生命周期发展机制等。

讲师

XCR15938761610@outlook.com

教育背景

2017.9-2022.8 博士就读于弗吉尼亚理工大学，遗传学、生物信息学和计算生物学项目。

2014.9-2017.9 硕士就读于山东大学数学与统计学院，运筹学与控制论专业，生物信息学方向。

2010.9-2014.9 本科就读于山东大学海洋学院，生物技术专业。

工作经历

2022.10-今 郑州大学生命科学学院 讲师

主要成果与奖励

论文：

- Chunrui Xu, John J. Tyson, Yang Cao, Turing-pattern model of scaffolding proteins that establish spatial asymmetry during the cell cycle of Caulobacter crescentus. (2023). iScience, accepted.

- Chunrui Xu, Henry Hollis, Michelle Dai, Xiangyu Yao, Layne T. Watson, Yang Cao, Minghan Chen. Modeling the temporal dynamics of master regulators and CtrA proteolysis in Caulobacter crescentus cell cycle. (2022).  PLOS Computational Biology, 18(1): e1009847.

- Minghan Chen, Chunrui Xu, Ziang Xu, Wei He, Haorui Zhang, Jing Su, Qianqian Song. Uncovering the dynamic effects of DEX treatment on lung cancer by integrating bioinformatic inference and multiscale modeling of scRNA-seq and proteomics data. (2022). Computers in Biology and Medicine, 149: 105999.

- Chunrui Xu, Bronson Weston, John Tyson, Yang Cao. Cell cycle control and environmental response by second messengers in Caulobacter crescentus. (2019). BMC Bioinformatics. 21(Suppl 14): 408.

- Shenghui Liu, Chunrui Xu, Yusen Zhang, Jiaguo Liu, Bin Yu, Xiaoping Liu, Matthias Dehmer. Feature selection of gene expression data for Cancer classification using double RBF-kernels. (2018). BMC Bioinformatics. 19: 396.

- Chunrui Xu, Li Ge, Yusen Zhang, Matthias Dehmer, Ivan Gutman. Computational prediction of therapeutic peptides based on graph index. (2017). Journal of Biomedical Informatics. 75: 63-69.

学术兼职

其他