陈鲤翔
教育经历：
1999.09–2004.07，兰州大学，生物化学与分子生物学专业，理学博士
1992.09–1996.07，兰州大学, 细胞生物学专业，理学学士
科研与学术工作经历：
2013.3-至今, 郑州大学, 生命科学学院, 副教授
2008.3-2013.3, 美国纽约血液中心, 博士后
2005.5-2008.3, 郑州大学, 生命科学学院, 讲师
1996.7-1999.8, 甘肃省金川公司职工医院, 检验科, 检验师
基本情况：
陈鲤翔，副教授，博士生导师。近年来主要从事造血发育调控机制研究，聚焦DNA甲基化/去甲基化和组蛋白修饰等多种表观遗传修饰协同调控红系发育研究方向。主持国家自然科学基金面上项目2项、河南省高等学校科技创新人才项目1项以及河南省自然科学基金项目1项，并作为主要人员参与国家自然科学基金重点和联合重点项目、科技部“十二五”“重大新药创制”科技重大专项等重要科研项目。在Blood、J Hematol Oncol、J Biol Chem、Cancer Letter等生物医学领域重要期刊发表SCI论文10余篇，出版中英文专著各1部，参编“十二五本科教学工程”教材1部，获授权国家发明专利1项，获河南省科学技术进步奖二等奖1项。
代表性论文（*通讯作者）：
1. Chen, Lixiang; Wang, Ting; Ji, Xiang; Ding, Cong; Liang, Taotao; Liu, Xin; Lu, Jike; Guo, Xinrui; Kang, Qiaozhen; Ji, Zhenyu. Cytoskeleton protein 4.1R suppresses murine keratinocyte cell hyperproliferation via activating the Akt/ERK pathway in an EGFR-dependent manner. Exp Cell Res. 2019; 384(2):111648.
2. Li, Wei; Wang, Yaomei; Zhao, Huizhi; Zhang, Huan; Xu, Yuanlin; Wang, Shihui; Guo, Xinhua; Huang, Yumin; Zhang, Shijie; Han, Yongshuai; Wu, Xianfang; Rice, Charles M.; Huang, Gang; Gallagher, Patrick G.; Mendelson, Avital; Yazdanbakhsh, Karina; Liu, Jing; Chen, Lixiang; An, Xiuli. Identification and transcriptome analysis of erythroblastic island macrophages. Blood. 2019; 134 (5): 480-491.
3. Qu, Xiaoli; Zhang, Shijie; Wang, Shihui; Wang, Yaomei; Li, Wei; Huang, Yumin; Zhao, Huizhi; Wu, Xiuyun; An, Chao; Guo, Xinhua; Hale, John; Li, Jie; Hillyer, Christopher D.; Mohandas Narla; Liu, Jing; Yazdanbakhsh, Karina; Vinchi, Francesca; Chen, Lixiang*; Kang, Qiaozhen; An, Xiuli. TET2 deficiency leads to stem cell factor-dependent clonal expansion of dysfunctional erythroid progenitors. Blood. 2018; 132(22):2406-2417.
4. Huang, Yumin; Hale, John; Wang, Yaomei; Li, Wei; Zhang, Shijie; Zhang, Jieying; Zhao, Huizhi; Guo, Xinhua; Liu, Jing; Yan, Hongxia; Yazdanbakhsh, Karina; Huang, Gang; Hillyer, Christopher D.; Mohandas, Narla; Chen, Lixiang*; Sun, Ling; An, Xiuli. SF3B1 deficiency impairs human erythropoiesis via activation of p53 pathway: implications for understanding of ineffective erythropoiesis in MDS , Journal of Hematology & Oncology, 2018; 11(1):19.
5. Wang, Yaomei; Zhang, Huizhen; Kang, Qiaozhen; Liu, Jing; Weng, Haibo; Li, Wei; Mohandas, Narla; An, Xiuli; Chen, Lixiang*. Protein 4.1N is required for the formation of the lateral membrane domain in human bronchialn epithelial cells. , Biochim Biophys Acta, 2018.2.8, 1860(5): 1143-1151.
6. Yan, Hongxia; Wang, Yaomei; Qu, Xiaoli; Li, Jie; Hale, John; Huang, Yumin; An, Chao; Papoin, Julien; Guo, Xinhua; Chen, Lixiang; Kang, Qiaozhen; Li, Wei; Schulz, Vincent P.; Gallagher, Patrick G.; Hillyer, Christopher D.; Mohandas, Narla; An, Xiuli , Distinct roles for TET family proteins in regulating human erythropoiesis , Blood, 2017. 129(14): 2002-2012
7. Chen, Lixiang; Wang, Ting; Wang, Yaomei; Zhang, Jingxin; Qi, Yuanming; Weng, Haibo; Kang, Qiaozhen; Guo, Xinghua; Baines, AJ; Mohandas, Narla; An, Xiuli. Prote in 4.1G Regulates Cell Adhesion, Spreading, and Migration of Mouse Embryonic Fibroblasts through the β1 Integrin Pathway. The Journal of Biological Chemistry, 2016. 291(5): 2170-2180
代表性论著
1. 安秀丽，陈鲤翔等，第三章：红细胞。基础血液学，程涛主编，科学出版社，2019年。
2. An, Xiuli; Chen, Lixiang. Flow Cytometry (FCM) Analysis and Fluorescence-Activated Cell Sorting (FACS) of Erythroid Cells. In: Lloyd J. (eds) Erythropoiesis. Methods in Molecular Biology, vol 1698. Humana Press, New York, NY, 2018
3. An, Xiuli; Chen, Lixiang. Flow Cytometric Analysis of Erythroblast Enucleation. , Flow Cytometric Analysis of Erythroblast Enucleation. In: Lloyd J. (eds) Erythropoiesis. Methods in Molecular Biology, vol 1698. Humana Press, New York, NY, 2018
4. 祁元明，陈鲤翔，王婷等，免疫学原理与技术，王玉炯、祁元明主编，高等教育出版社，2016年。
近期获授权专利：
1. FAP来源的抗肿瘤CTL表位肽P265及其应用。专利号：ZL201610361347.8