姓名：李昂
职务/职称：副研究员
工作单位：郑州大学第一附属医院
办公室：郑大一附院东院区河南省基因医院办公室
邮箱：lia@zju.edu.cn
研究领域：人工智能在临床医学的应用,数据可视化,病原微生物基因组&宏基因组的计算，肝病的创新诊治
教育背景：(1) 2013-09至2017-03,浙江大学,内科学,博士
(2) 2009-09至2012-06,华南理工大学,生物工程,硕士
(3) 2005-09至2009-06,郑州大学,生物技术,学士
教学情况：《精准医学》研究生课程
科研项目：(1)国家科技部,国家科技部重点项目, 2018ZX10305410,基于宏基因组学的病原微生物快速诊断技术开发-子课题7-任务四, 2018-01至2021-12, 180万元,结题,主持
(2)抗病毒传染病创新药物全国重点实验室专项,mNGS病原检测可靠度评估及临床效能等级分级。2024年度40万元 在研 主持
发表论文：（第一作者或通讯作者）
[1]Wang H, Hu J, Wang D, Cai Y, Zhu W, Deng R, Zhang Y, Dong Z, Yang Z, Xiao J,Li A,Liu Z. TM9SF1 inhibits colorectal cancer metastasis by targeting Vimentin for Tollip-mediated selective autophagic degradation. Cell Death Differ. 2025 Apr 2.
[2]Wang H, Zhu W, Lei J, Liu Z, Cai Y, Wang S,Li A.Gut microbiome differences and disease risk in colorectal cancer relatives and healthy individuals. Front Cell Infect Microbiol. 2025 Mar 24;15:1573216.
[3]Wang, Chong;Li, Ang;Shi, Qingmiao; Yu, Zujiang ; Metagenomic next-generation sequencing clinches diagnosis of leishmaniasis, Lancet, 2021, 397(10280): 1213
[4]Li, Ang;Gabriel, Vinderola; Akihito, Endo; Juha, Kantanen; Chen, Jingfeng; Ana, Binett; Patricia, Burns; Shi, Qingmiao; Ding, Suying; Yu, Zujiang; David, Rios-Covian; Anastasia,Mantziari; Shea, Beasley; Carlos, Gomez-Gallego; Miguel, Gueimonde; Seppo, Salminen ; Gut microbiome characteristics in feral and domesticated horses from different geographic locations, Communications Biology, 2022, 5(1): 172
[5]Li, Ang; Li, Tiantian; Gao, Xinxin; Yan, Hang; Chen, Jingfeng; Huang, Meng; Wang, Lin;Yin, Detao; Li, Hongqiang; Ma, Runsheng; Zeng, Qiang; Ding, Suying ; Gut microbiome alterations in patients with thyroid nodules, Frontiers in Cellular and Infection Microbiology, 2021, 11:643968
[6]Yan, Su; Ma, Zhonghui; Jiao, Mengfan; Wang, Youxiang;Li, Ang; Ding, Suying ; Effects of smoking on inflammatory markers in a healthy population as analyzed via the gut microbiota, Frontiers in Cellular and Infection Microbiology, 2021, 11: 633242
[7]Qin N*, Yang F*, Li Ang*, Prifti E*, Chen Y*, Shao L*, Guo J, Le Chatelier E, Yao J, Wu L, Zhou J, Ni S, Liu L, Pons N, Batto JM, Kennedy SP, Leonard P, Yuan C, Ding W, Chen Y, Hu X, Zheng B, Qian G, Xu W, Ehrlich SD*, Zheng S*, Li L*. Alterations of the human gut microbiome in liver cirrhosis. Nature. 2014. , 513(7516):59-64.
获得奖励：郑州大学青年拔尖人才
社会兼职：河南省科学保健学会保健大数据专委会常委 河南省预防医学会会员 河南省预防医学会微生态专业委员会委员
