姓名：郭艳春

性别：女

出生年月：1972.02

职称：讲师

民族：汉

籍 贯：河南郑州

电子邮箱：Ycguo@zzu.edu.cn

最终学位：博士

联系方式：13513805672

实验室：郑州大学南校区教学22号楼307

研究方向

有机质谱，有机杂环化学,有机磷化学

主要学习、科研和工作经历

2010.10--至今 郑州大学化学学院 讲师

2016.9--2017.12 美国南加州大学 化学系 访问学者

2006.9--2009.12 郑州大学 有机化学 博士

2003.9--2006.6 郑州大学 有机化学 硕士

1990.9--1994.6 河南大学 化学 学士

代表性

教学成果与荣誉

2018.12《医用化学》线下精品课程

代表性

科研成果

一、科研项目

1. 2012.01-2014.12 利用ESI-MS技术研究环二肽与金属离子间的相互作用 国家自然科学基金青年基金项目No.21105091 25万元

2. 2018.10-2019.09 合成特定的含有端炔的双吖丙啶化合物 横向项目 No.20180361A 5万元

3. 2020.05-2021.04 农产品贮藏加工常见危害因子的快速检测—核磁共振技术的应用 横向项目No.20200091A 2万元

二、论文论著

1. Yanchun Guo*, Han Xue, Shigai Li, Yanyan Wang, Yuexiu Wang, Shuxia Cao,Yufen Zhao,Electrospray ionization collision induced dissociation of thieno[3,2-d] pyrimidine derivatives,International Journal of Mass Spectrometry,2020, 457,116411

2. Yanchun Guo*, Yuexiu Wang, Han Xue, Shuxia Cao, Yufen Zhao, I₂- mediated and direct synthesis of 3-phenoxy imidazo heterocycles,Tetrahedron,2019, 75, 1481-1491

3. Miaomiao Peng, Shaozhu Li, Jing Wu, Yanchun Guo*, Shuxia Cao, Yufen Zhao,

Fragmentation studies of sartans by electrospray ionization mass spectrometry,

Journal of Mass Spectrometry,2017, 52, 591-596

4. Xi-Feng Zhu, Jing Zhang, Shuo Sun, Yan-ChunGuo*, Shu-Xia Cao,Yu-Fen Zhao, Synthesis and structure-activity relationships study of a-aminophosphonate derivatives containing a quinoline moiety,Chinese Chemical Letters,2017, 28, 1514-1518.

5. Yan-Chun Guo, Jing Li, Jiao-Li Ma, Zhi-Ran Yu,Hai-Wei Wang, Wen-Juan Zhu, Xin-Cheng Liao, Yu-fen Zhao, Synthesis and antitumor activity α-amino phosphonate derivatives containing thieno[2,3-d] pyrimidines,Chinese Chemical Letters,2015, 26, 755–758.

6. ChaoHan, Yan-Chun Guo, Dan-Dan Wang,Xing-Jie Dai, Feng-Juan Wu, Huan-Fei Liu, Gui-Fu Dai, Jing-Chao Tao, Novel pyrazole fused heterocyclic ligands: Synthesis, characterization, DNA binding/cleavage activity and anti-BVDV activity,Chinese Chemical Letters,2015, 26, 534–538.

7. Zhu Xi-Feng, Guo Yan-Chun*, Yu Zhi-Ran, Liao Xin-Cheng, Zhao Yu-Fen,

Syntheses and Crystal Structures of Two New α-Amino phosphonate Derivatives Containing Thieno[2,3-d]pyrimidine,Chinese J. Struct. Chem.,2015, 34(6), 879-884.

8. Xiaohui You, Lin Qi, Jia Zheng, Wang Dai, Yanchun Guo, Yufen Zhao, Shuxia Cao, Synthesis and Characterization of New Pyrospirophosphoranes Containing a P-O-P Bond by the Atherton–Todd Reaction, Heteroatom Chemistry,2015, 26(2), 168-174

9. ShuxiaCao, Peng Gao, Yanchun Guo, HuaminZhao, Jun Wang, Yifan Liu, Yufen Zhao, Unexpected insertion of CO₂into the pentacoordinate P-N Bond: Atherton

–Todd- type reaction of Hydrospirophosphorane with amines.Journal of Organic Chemistry, 2013, 78 (22), 11283–11293.

10. Shuxia Cao, Yanchun Guo, Jun Wang, Lin Qi, Peng Gao, Huamin Zhao, Yufen Zhao,Preliminary stereochemical investigation of the Atherton-Todd-type reaction between valine hydrospirophosphorane and phenols,Tetrahedron Letters,2012, 53, 6302-6305.

11. Yanchun Guo, Shuxia Cao, Yali Xie, Xiangkun Zong, Yufen Zhao, Investigation

of ReactionMechanism of Amino Acids and Phosphorus Trichloride by³¹P NMR and ESI-MS/MS,Chinese Journal of Chemistry,2011, 29, 1173-1179

12. Shuxia Cao, Yanchun Guo, Xinshuai Wu, Huamin Zhao, Yufen Zhao, Fragmentation studies of pentacoordinated bisaminoacyls-pirophosphoranes

by negative electrospray ionization mass spectrometry,Journal of Mass Spectrometry,2011, 46, 352-358.

三、专利

郭艳春，王月秀，曹书霞，赵玉芬.一种咪唑并[1,2-a]吡啶衍生物的制备方法：中国，108690018A[P].2018-10-23.