牛俊龙,教授、高级工程师、博士生导师。河南省特聘教授,河南省杰出青年基金获得者,河南省教育厅学术技术带头人,河南省科技创新人才。主要从事金属有机化学研究,主持多项国家自然科学基金面上和青年项目、省级以及校级科研项目;作为通讯作者,在Nature Synthesis、Angewandte Chemie International Edition、Nature Communications、Chemical Science、ACS Catalysis等发表研究论文40余篇,多篇论文被Nat. Synth.、Synfact和《有机化学》等期刊作为亮点介绍;参编出版教材3部;讲授本科生《有机合成化学》、《有机化学实验》和博士研究生《金属有机化学进展》等课程。
联系方式:
niujunlong@zzu.edu.cn
学习经历:
2000.09-2004.06,郑州大学化学系,学士
2004.09-2009.06,郑州大学化学系,硕博连读(导师:宋毛平教授)
工作经历:
2009/06 - 2011/06,郑州大学材料科学与工程博士后流动站,博士后(合作导师:赵清香教授)
2011/10 - 2017/12,郑州大学,化学与分子工程学院,副教授/硕士生导师
2019/03 - 2020/03,香港科技大学,化学系,访问学者(合作导师:孙建伟教授)
2018.01 - 至今, 郑州大学化学学院,教授/博士生导师
研究方向:
以丰产金属为催化剂,通过发展新试剂、新方法和新策略,实现碳氢键、碳碳健、碳杂原子键断裂和重组的有机合成反应,完成惰性化学键的精准切断以及转化反应的高区域选择性和高立体选择性控制。
主持项目:
1. 河南省杰出青年基金(242300421033),2025-2027
2. 河南省科技研发计划联合基金(优势学科培育类)重点项目(232301420007),2024-2026
3. 国家自然科学基金面上项目(22271260),2023-2026
4. 郑州大学青年人才创新团队支持计划,2021-2023
5. 河南省高校科技创新人才支持计划(19HASTIT038),2019-2020
6. 国家自然科学基金面上项目(21772179),2018-2021
7. 国家自然科学青年基金(21502173),2016-2018
8. 河南省高等学校重点科研项目(16A150024), 2016-2017
9. 郑州大学优秀青年教师发展基金(1521316002), 2016-2018.
10. 河南省博士后科研项目壹等资助
所获荣誉:
1. 2015-2016、2019-2020 郑州大学工会积极分子
2. 2016-2017 郑州大学“三育人”先进个人
3. 2016-2017 化学院“优秀共产党员”
4. 河南省优秀博士后
代表性论文:
1. Yuanshuo Zhang, Shuang-Liang Liu, Tong Li, Miao Xu, Qiuling Wang, Dandan Yang*, Mao-Ping Song, Jun-Long Niu*. “N,O-Auxiliary Enabled Cobaltaelectro-Catalyzed Atroposelective C−H Annulation”, ACS Catal. 2024, 14, 1-9
2. Yingjie Sun, Taixin Yang, Qiuling Wang, Linlin Shi*, Mao-Ping Song, Jun-Long Niu*.“Atroposelective N-N axes synthesis via electrochemical cobalt catalysis”, Org. Lett. 2024, 26, 5063–5068
3. Liming Zhang, Chen Yang, Xinhai Wang, Taixin Yang, Dandan Yang, Yingchao Dou*, Jun-Long Niu*.“Enantioselective Electrosynthesis of Inherently Chiral Calix[4]arenes via a Cobalt-Catalyzed Aryl C-H Acyloxylation”, Green Chem., 2024, 26, 10232-10239.
4. Tong Li, Yanbo Zhang, Cong Du, Dandan Yang,* Mao-Ping Song, Jun-Long Niu*. “Simultaneous Construction of Inherent and Axial Chirality by Cobalt-Catalyzed Enantioselective C-H Activation of Calix[4]arenes”, Nat. Commun. 2024, 15, 7673.
5. Tong Li, Linlin Shi, Xinhai Wang, Chen Yang, Dandan Yang*, Mao-Ping Song, Jun-Long Niu*.“Cobalt-catalyzed atroposelective C−H activation/annulation to access N−N axially chiral frameworks”, Nature Communications, 2023, 14, 5271.
6. Xinhai Wang, Xiao-Ju Si, Yingjie Sun, Zhisen Wei, Miao Xu, Dandan Yang, Linlin Shi*, Mao-Ping Song, Jun-Long Niu*.“C-N Axially chiral heterobiaryl isoquinolinone skeletons construction via cobalt-catalyzed atroposelective C-H activation/annulation”, Organic letters, 2023, 25, 6240.
7. Tong Li, Linlin Shi, Xiaofang Zhao, Jianli Wang, Xiao-Ju Si, Dandan Yang,* Mao-Ping Song, Jun-Long Niu*.“C–N Axially Chiral Heterobiaryl Skeletons Construction via Cobalt-Catalyzed Atroposelective Annulation”, Organic letters, 2023, 25, 5191.
8. Xiao-Ju Si, Xiaofang Zhao, Jianli Wang, Xinhai Wang, Yuanshuo Zhang, Dandan Yang,* Mao-Ping Song, Jun-Long Niu*.“Cobalt-catalyzed Enantioselective C-H/N-H Annulation of Aryl Sulfonamides with Allenes or Alkynes: Facile access to C-N Axially Chiral Sultams”, Chemical Science, 2023, 14, 7291.
9. Dandan Yang, Xian Zhang, Xinghua Wang, Xiao-Ju Si, Jingtao Wang, Donghui Wei,* Mao-Ping Song,* Jun-Long Niu*.“Cobalt-Catalyzed Enantioselective C-H Annulation with Alkenes”, ACS Catalysis, 2023, 13, 4250.
10. Xiao-Ju Si, Dandan Yang, Meng-Chan Sun, Donghui Wei, Mao-Ping Song, Jun-Long Niu*.“Atroposelective Isoquinolinone Synthesis Through Cobalt-catalysed C-H Activation and Annulation”, Nature Synthesis, 2022, 1, 709.
11. He Zhang, Dandan Yang, Xiao-Fang Zhao, Jun-Long Niu*, Mao-Ping Song*. “Cobalt-catalyzed C(sp3)-H bond functionalization to access indole derivatives”, Organic Chemistry Frontiers, 2022, 9, 3723
12. Xin Yu, Zhuo-Zhuo Zhang, Jun-Long Niu*, and Bing-Feng Shi*.“Coordination-Assisted, Transition-Metal-Catalyzed Enantioselective Desymmetric C-H Functionalization”, Organic Chemistry Frontiers, 2022, 9, 1458-1484
13. Li-Ming Yin, Meng-Chan Sun, Xiao-Ju Si, Dandan Yang*, Mao-Ping Song, Jun-Long Niu*.“Nickel-Catalyzed anti-Markovnikov Hydrodifluoroalkylation of Unactivated Alkenes”,Organic letters, 2022, 24, 1083.
14. He Zhang, Meng-Chan Sun, Dandan Yang*, Tong Li, Mao-Ping Song*, Jun-Long Niu*.“Cobalt(II)-Catalyzed Activation of C(sp3)-H Bonds: Organic Oxidant Enabled Selective Functionalization”,ACS Catalysis, 2022, 12, 1650.
15. He Zhang, Meng-Chan Sun, Li-Ming Yin, Donghui Wei,* Mao-Ping Song,* Dandan Yang, Jun-Long Niu*.“Direct intramolecular C(sp3)-H bond sulfonamidation to synthesize benzosultam derivatives under metal-free conditions”,Organic Chemistry Frontiers, 2021, 8, 6888–6894.
16. Dandan Yang, Hai Huang, He Zhang, Li-Ming Yin, Mao-Ping Song*, Jun-Long Niu*.“Regioselective Intermolecular Hydroamination of Unactivated Alkenes: “Co-H” Enabled Remote Functionalization”, ACS Catalysis, 2021, 11, 6602.
17. Meng-Hui Li, Xiao-Ju Si, He Zhang, Dandan Yang,* Jun-Long Niu*, Mao-Ping Song.“Directed Cobalt-Catalyzed C-H Activation to Form C-C and C-O Bonds in One Pot via Three-Component Coupling”,Organic letters, 2021, 23, 914.
18. Dandan Yang, Hai Huang, Meng-Hui Li, Xiao-Ju Si, He Zhang, Jun-Long Niu*, Mao-Ping Song*.“Directed Cobalt Catalyzed anti-Markovnikov Hydroalkylation of Unactivated Alkenes Enabled by “Co-H” Catalysis”, Organic letters, 2020, 22, 4333.
19. Qingkai Yan, Hai Huang, He Zhang, Meng-Hui Li, Dandan Yang*, Mao-Ping Song, Jun-Long Niu*.“Synthesis of 7-Amido Indolines by Cp*Co(III)-Catalyzed C-H Bond Amidation”, Journal of Organic Chemistry, 2020, 85, 11190.
20. Cai-Ling Fan, Lin-Bao Zhang, Jia Liu, Xin-Qi Hao, Jun-Long Niu*, Mao-Ping Song*.“Copper-Mediated Direct Sulfonylation of C(sp2)-H Bond Employing TosMIC as a Sulfonyl Source”, Organic Chemistry Frontiers, 2019, 6, 2215.
21. Xiao-Cai Li, Cong Du, He Zhang, Jun-Long Niu*, Mao-Ping Song*.“Cp*-free cobalt-catalyzed C-H Activation/Annulation by Traceless N,O-bidentate directing group: Access to Isoquinolines”, Organic letters, 2019, 21, 2863.
22. Cong Du, Peng-Xiang Li, Xinju Zhu, Jiao-Na Han, Jun-Long Niu*, Mao-Ping Song*.“Cobalt-Catalyzed Oxidative C−H/N−H Cross-Coupling: Selective and Facile Access to Triarylamines”, ACS Catalysis, 2017, 7, 2810.
23. Xinju Zhu, Jian-Hang Su, Cong Du, Zheng-Long Wang, Chang-Jiu Ren, Jun-Long Niu*, Mao-Ping Song*.“Cobalt(II)-Catalyzed Oxidative C−H Arylation of Indoles and Boronic Acids”, Organic letters, 2017, 19, 596.
24. Cong Du, Peng-Xiang Li, Xinju Zhu, Jian-Feng Suo, Jun-Long Niu*, Mao-Ping Song*.“Mixed Directing Group Strategy: Oxidative C−H/C−H Bond Arylation of Unactivated Arenes by Cobalt Catalysis”, Angewandte Chemie International Edition, 2016, 55, 13571.
25. Xin-Qi Hao, Cong Du, Xinju Zhu, Peng-Xiang Li, Jia-Heng Zhang, Jun-Long Niu*, Mao-Ping Song*.“Cobalt(II)-Catalyzed Decarboxylative C–H Activation/Annulation Cascades: Regioselective Access to Isoquinolones and Isoindolinones”, Organic letters, 2016, 18, 3610.
26. Donghui Wei, Xinju Zhu, Jun-Long Niu*, Mao-Ping Song*.“High-Valent Cobalt-Catalyzed C−H Functionalization Based on Concerted Metalation-Deprotonation and Single-Electron-Transfer Mechanisms”, ChemCatChem, 2016, 8, 1242. (Invited Review Paper and Selected as a Front Cover).
27. Lin-Bao Zhang, Shou-Kun Zhang, Donghui Wei, Xinju Zhu, Xin-Qi Hao, Jian-Hang Su, Jun-Long Niu*, Mao-Ping Song*.“Cobalt(II)-Catalyzed C–H Amination of Arenes with Simple Alkylamines”, Organic letters, 2016, 18, 1318.
28. Lin-Bao Zhang, Xin-Qi Hao, Zhan-Jiang Liu, Xin-Xiang Zheng, Shou-Kun Zhang, Jun-Long Niu*, Mao-Ping Song*.“Cobalt(II)-Catalyzed C(sp2)-H Alkynylation/Annulation with Terminal Alkynes: Selective Access to 3-Methyleneisoindolin-1-one”, Angewandte Chemie International Edition, 2015, 54, 10012.
29. Lin-Bao Zhang, Xin-Qi Hao, Shou-Kun Zhang, Zhan-Jiang Liu, Xin-Xiang Zheng, Jun-Fang Gong, Jun-Long Niu*, Mao-Ping Song*.“Cobalt-Catalyzed C(sp2)-H Alkoxylation of Aromatic and Olefinic Carboxamides”, Angewandte Chemie International Edition, 2015, 54, 272.
30. Xiao-Kang Guo, Lin-Bao Zhang, Donghui Wei*, Jun-Long Niu*.“Mechanistic Insights into the Cobalt(II/III)-Catalyzed C-H Oxidation: A Combined Theoretical and Experimental Study”, Chemical Science, 2015, 6, 7059.
31. Xin-Qi Hao, Li-Juan Chen, Baozeng Ren, Liu-Yan Li, Xin-Yan Yang, Jun-Fang Gong, Jun-Long Niu*, Mao-Ping Song*.“Copper-mediated Direct Aryloxylation of Benzamides Assisted by an N,O-Bidentate Directing Group”, Organic letters, 2014, 16, 1104.