蓝宇

作者: 时间:2021-04-03 点击数:

蓝宇,2003年和2008年在北京大学完成获本科和博士学位,2009年至2012年在美国加州大学洛杉矶分校从事博士后研究。2012年加入重庆大学化学化工学院独立开展科学研究。2018年,蓝宇博士聘入郑州大学,任教授、博士生导师、化学学院副院长。蓝宇博士工作聚焦反应机制调控下的功能分子精准合成。通过对合成反应进行理性设计,实现原理和机制指导的功能分子精准合成。蓝宇入选第六批国家高层次人才特殊支持计划科技创新领军人才,入选第十一批河南省优秀专家,入选河南省特聘教授。蓝宇2021年获科技部中青年科技创新领军人才资助,2018年获国家自然科学基金优秀青年基金资助。蓝宇获2016年中国化学会青年化学奖,2018年重庆市自然科学奖一等奖(第一完成人),2019ACP Lectureship Award2021年河南省教育厅优秀科技论文奖一等奖,2019年第十四届河南省青年科技奖。

 

联系方式:LanYu@zzu.edu.cn

 

研究方向

 

 光催化物质转化

 机制导向的精准合成

 均相催化反应机制

 

项目和经费:

 

(6) 2021~2023 科技部中青年科技创新领军人才 《机制导向的精准合成》,80主持)

(5) 2020~2022 河南省高校科技创新人才项目《有机化学》60万,基金号20HASTIT004(主持)

(4) 2019~2021 自然科学基金优秀青年基金项目《理论有机化学》130万,基金号21822303(主持)

(3) 2018~2021 自然科学基金面上项目《铜催化偶联反应中Cu(III)中间体生成机制的理论研究》64万,基金号21772020(主持)

(2) 2014~2017 自然科学基金面上项目《铑催化碳-硅键、碳-碳键断裂生成机理的理论研究》80万,基金号21372266(主持)

(1) 2014~2016 自然科学基金青年项目《单层石墨烯化学方法修饰的理论研究》25万,基金号51302327(主持)

 

近期代表作:

著作

(2) “Computational Methods in Organometallic Catalysis” Lan, Y. WILEY-VCH GmbH, Germany, 2021. (ISBN: 978-3-527-34601-1)

(1) “Computational Advances of Rh-Catalyzed C–H Functionalization” Lan, Y.; Cui, C.-X.; Liu, S.; Li, C.-X.; Bai, R. Springer Nature, Singapore, 2021. (ISBN: 978-981-16-0431-7; DOI: 10.1007/978-981-16-0432-4)

 

论文

1. “Structure, reactivity and catalytic properties of manganese-hydride amidate complexes” Wang, Y.; Liu, S.; Yang, H.; Li, H.; Lan, Y.*; Liu, Q.* Nat. Chem. 2022, 14, 1233-1241.

2. Yang, L.-C.; Wang, Y.-N.; Liu, R.; Luo, Y.; Ng, X. Q.; Yang, B.; Rong, Z.-Q.; Lan Y.*; Shao, Z.; Zhao, Y.* Nat. Chem. 2020, 12, 860-868.

3. “Diradical Generation via Relayed Proton-Coupled Electron Transfer” Shi, Q.; Pei, Z.; Song, J.; Li, S.-J.; Wei, D.*; Coote, M. L.*; Lan, Y.* J. Am. Chem. Soc. 2022, 144, 3137-3145.

4. “Chiral Phosphoric Acid Catalyzed Conversion of Epoxides into Thiiranes: Mechanism, Stereochemical Model, and New Catalyst Design” Duan, M.; Díaz-Oviedo, C. D.; Zhou, Y.; Chen, X.; Yu, P.; List, B.*; Houk, K. N.*; Lan, Y.* Angew. Chem. Int. Ed. 2022, 61, e202113204.

5. “Recent Advances in Theoretical Studies on Transition-Metal-Catalyzed Carbene Transformations” Qi, X.*; Lan, Y.* Acc. Chem. Res. 2021, 54, 2905-2915.

6. “Mechanism of Rhodium-Catalyzed C−H Functionalization: Advances in Theoretical Investigation” Qi, X.; Li, Y.; Bai, R.; Lan, Y.* Acc. Chem. Res. 2017, 50, 2799-2808.

7. “Boryl Radical Activation of Benzylic C−OH Bond: Cross-Electrophile Coupling of Free Alcohols and CO2 via Photoredox Catalysis” Li, W.-D.; Wu, Y.; Li, S.-J.; Jiang, Y.-Q.; Li, Y.-L.; Lan, Y.*; Xia, J.-B.* J. Am. Chem. Soc. 2022, 144, 8551-8559.

8. “Palladium-Catalyzed Enantioselective Carbene Insertion into Carbon−Silicon Bonds of Silacyclobutanes” Huo, J.; Zhong, K.; Xue, Y.; Lyu, M.; Ping, Y.; Liu, Z.; Lan, Y.*; Wang, J.* J. Am. Chem. Soc. 2021, 143, 12968-12973.

9. “Benzyne 1,2,4-Trisubstitution and Dearomative 1,2,4-Trifunctionalization” Shi, J.; Li, L.; Shan, C.; Chen, Z.; Dai, L.; Tan, M.; Lan, Y.*; Li, Y.* J. Am. Chem. Soc. 2021, 143, 10530-10536. (DOI: 10.1021/jacs.1c04389)

10. “Desymmetrization of 1,3-Diones by Catalytic Enantioselective Condensation with Hydrazine” Yang, B.; Dai, J.; Luo, Y.; Lau, K. K.; Lan, Y.*; Shao, Z.*; Zhao, Y.* J. Am. Chem. Soc. 2021, 143, 4179-4186. (DOI: 10.1021/jacs.1c01366)

11. “Aryne 1,2,3,5-Tetrasubstitution Enabled by 3‑Silylaryne and Allyl Sulfoxide via an Aromatic 1,3-Silyl Migration” Shi, J.; Li, L.; Shan, C.; Wang, J.; Chen, Z.; Gu, R.; He, J.; Tan, M.; Lan, Y.*; Li, Y.* J. Am. Chem. Soc. 2021, 143, 2178-2184.

12. “Nickel-Catalyzed Cross-Redistribution between Hydrosilanes and Silacyclobutanes” Chen, S.; He, X.; Jin, C.; Zhang, W.; Yang, Y.; Liu, S.; Lan, Y.*; Houk, K. N.*; Shen, X.* Angew. Chem. Int. Ed. 2022, 61, e202213431.

13. “Enantioselective Synthesis of Spirosilabicyclohexenes by Asymmetric Dual Ring Expansion of Spirosilabicyclobutane with Alkynes” Chen, H.; Peng, J.; Pang, Q.; Du, H.; Huang, L.; Gao, L.; Lan, Y.*; Yang, C.*; Song, Z.* Angew. Chem. Int. Ed. 2022, 61, e202212889.

14. “Catalytic Multicomponent Synthesis of C-Acyl Glycosides by Consecutive Cross-Electrophile Couplings” Jiang, Y.; Yang, K.; Wei, Y.; Wang, Q.*; Li, S.-J.*; Lan, Y.*; Koh, M. J.* Angew. Chem. Int. Ed. 2022, 61, e202211043.

15. “Regio- and Stereoselective 1,2-Oxyhalogenation of Non-Conjugated Alkynes via Directed Nucleopalladation: Catalytic Access to Tetrasubstituted Alkenes” Liu, M.; Sun, J.; Zhang, T.; Ding, Y.; Han, Y.-Q.; Martín-Montero, R.; Lan, Y.*; Shi, B.-F.*; Engle, K. M.* Angew. Chem. Int. Ed. 2022, 61, e202209099.

16. “The Stannum–Ene Reactions of Benzyne and Cyclohexyne with Superb Chemoselectivity for Cyclohexyne” Li, L.; Shan, C.; Shi, J.; Li, W.; Lan, Y.*; Li, Y.* Angew. Chem. Int. Ed. 2022, 61, e202117351.

17. “Deoxygenative Cross-Coupling of Aromatic Amides with Polyfluoroarenes” He, Y.; Wang, Y.; Li, S.-J.; Lan, Y.*; Wang, X.* Angew. Chem. Int. Ed. 2022, 61, e202115497.

18. “Experimental and Computational Studies on the Directing Ability of Chalcogenoethers in Palladium-Catalyzed Atroposelective C-H Olefination and Allylation” Liao, G.; Zhang, T.; Jin, L.; Wang, B.-J.; Xu, C.-K.; Lan, Y.*; Zhao, Y.*; Shi, B.-F.* Angew. Chem. Int. Ed. 2022, 61, e202115221.

19. “Rhodium-Catalyzed Atroposelective Construction of Indoles via C-H Bond Activation” Sun, L.; Chen, H.; Liu, B.; Chang, J.; Kong, L.; Wang, F.*; Lan, Y.*; Li, X.* Angew. Chem. Int. Ed. 2021, 60, 8391-8395.

20. “Elemental sulfur enabled divergent synthesis of disulfides, diselenides and polythiophenes from β-CF3-1,3-enynes” Jin, S.; Li, S.-J.; Ma, X.; Su, J.; Chen, H.; Lan, Y.*; Song, Q.* Angew. Chem. Int. Ed. 2021, 60, 881-888.

21. “Manganese-Catalyzed Asymmetric Hydrogenation of Quinolines Enabled by π-π Interaction” Liu, C.; Wang, M.; Liu, S.; Wang, Y.; Peng, Y.; Lan, Y.*; Liu, Q.* Angew. Chem. Int. Ed. 2021, 60, 5108-5113. (DOI: 10.1002/anie.202013540)

 

 

 

 

 

 

 

 

 

 

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