张家恒,1994年,理学博士,直聘副研究员
邮箱:zhangjiaheng@zzu.edu.cn; zhangjiaheng0123@163.com.
学习经历:
2011.09—2015.06 郑州大学,化学(本硕连读),理学学士;
2015.09—2017.06 郑州大学,有机化学(本硕连读),理学硕士;
2017.09—2021.11 湖南大学,分析化学,理学博士。
工作经历:
2022.08--至今 郑州大学 化学学院&现代分析与基因测序中心
研究方向:
多功能荧光探针的设计、合成及生物成像
主持项目:
[1] 国家自然科学基金青年项目(No.22304165),基于激活型G-四链体光声/荧光探针的癌症双模态成像研究,主持,在研。
[2] 中国博士后科学基金面上资助第74批(No.2023M743169),主持,在研。
[3] 郑州大学求是科研启动基金(No.32213308),近红外G-四链体荧光探针的设计及生物成像研究,主持,在研。
[4] 国家自然科学基金重点项目(No.22034002),基于新型CRISPR/Cas蛋白工具创建的病毒精准诊断与成像研究,参与,在研。
代表论文:
[1] Jiaheng Zhang, Huiyi Li, Bin Lin, Xingyu Luo, Peng Yin, Ting Yi, Binbin Xue, Xiao-Lian Zhang, Haizhen Zhu, and Zhou Nie*. Development of near-infrared nucleic acid mimics of fluorescent proteins for in vivo imaging of viral RNA with turn-on fluorescence. Journal of the American Chemical Society. 2021, 143, 19317–19329.
[2] Yuanchun Du, Zhenyi Ke , Jiaheng Zhang * and Guangfu Feng*. Dual-signal output paper sensor based on coordinative self-assembly biomimetic nanozyme for point-of-care detection of biomarker. Biosens Bioelectron. 2022, 216, 114656.
[3] Kai Shi, Jiaxuan Chen, Yuhao Li, Qiong Li, Jiuhua Song, Zhigang Yi, Daxiu Li, Jiaheng Zhang*. Hg2+-triggered cascade strand displacement assisted CRISPR-Cas12a for Hg2+ quantitative detection using a portable glucose meter. Analytica Chimica Acta. 2023, 1278, 341756.
[4] Guangfu Feng, Huaizu Zhang, Xiaohua Zhu, Jiaheng Zhang* and Jun Fang*. Fluorescence Thermometer: Intermediation of the Fontal Temperature and Light. Biomaterials Science. 2022, 10, 1855.
[5] Jiaheng Zhang, Xinqi Hao, Zhenglong Wang, Changjiu Ren, Junlong Niu*, Maoping Song*. Cobalt-Catalyzed C-H Benzylation of 8-Aminoquinolines on C(5) Position. Chin. J. Org. Chem. 2017, 37, 1237.
[6] Jiaheng Zhang, Chunyang Lei, Zhou Nie*. Application Advances of G-quadruplex Probes in Virus Gene Detection and Imaging. Journal of Instrumental Analysis. 2022, 41, 43.