职称：讲师
邮箱：yuetengzhang@zzu.edu.cn
地址：郑州大学基础医学院A1-634
个人简介
博士毕业于美国亚利桑那大学，从事药物开发领域，致力于开发新的可持续合成技术以构建具有生物和医学价值的分子结构。
主要研究方向
生物活性小分子合成方法学研究和抗肿瘤药物研发以及天然产物结构优化
课题组成员
李梦龙（硕士研究生）
荣誉及获奖情况
主持中国博士后基金面上项目1项和河南省自然科学青年基金1项，主要研究结果发表在ACS Catalysis，Communications Chemistry，Chemistry—A European Journal等期刊。
代表性成果
1. Ma L, Li M, Zhang Y*, Liu K*. Recent advances of antitumor leading compound Erianin: Mechanisms of action and structural modification. Eur J Med Chem, 2023, 261:115844.
2.Zhang Y, Zhang J, Li M, Qiao Y, Wang W, Ma L*, Liu K*. Target discovery of bioactive natural products with native-compound-coupled CNBr-activated Sepharose 4B beads (NCCB): Applications, mechanisms and outlooks. Bioorg Med Chem, 2023, 96:117483.
3.Ma L, Li M, Gou S, Wang W, Liu K*, Zhang Y*. Native-compound-Coupled Affinity Matrix (NCAM) in target identification and validation of bioactive compounds: Application, mechanism and outlooks. Bioorg Chem, 2023, 140:106828.
4.Zhang Y, Ji P, Gao F, Dong Y, Huang H, Wang C, Zhou Z, Wang W*. Organophotocatalytic dearomatization of indoles, pyrroles and benzo(thio)furans via a Giese-type transformation. Commun Chem, 2021, 4(1):20.
5.Zhang Y, Ji P, Meng X, Gao F, Zeng F, Wang W*. Facile Synthesis of 2H-Benzo[h]Chromenes via an Arylamine-Catalyzed Mannich Cyclization Cascade Reaction. Molecules, 2021, 26(12):3617.
6.Ji P, Zhang Y, Gao F, Bi F, Wang W*. Direct, stereoselective thioglycosylation enabled by an organophotoredox radical strategy. Chem Sci, 2020, 11(48):13079-13084.
7.Ji P, Zhang Y, Dong Y, Huang H, Wei Y, Wang W*. Synthesis of Enantioenriched α-Deuterated α-Amino Acids Enabled by an Organophotocatalytic Radical Approach.Org Lett, 2020, 22(4):1557-1562.
8.Zhang Y, Ji P, Dong Y, Wei Y, Wang W*. Deuteration of Formyl Groups via a Catalytic Radical H/D Exchange Approach. ACS Catal, 2020, 10(3):2226-2230.
9.Zhang Y, Ji P, Hu W, Wei Y, Huang H, Wang W*. Organocatalytic Transformation of Aldehydes to Thioesters with Visible Light. Chemistry, 2019, 25(35):8225-8228.
10.Ji P, Zhang Y, Wei Y, Huang H, Hu W, Mariano PA*, Wang W*. Visible-Light-Mediated, Chemo- and Stereoselective Radical Process for the Synthesis of C-Glycoamino Acids. Org Lett, 2019, 21(9):3086-3092.
