徐霞

郑州大学药学院教授，硕士生导师

美国加州大学访问学者

仪器仪表协会药物分析过程与控制协会主任委员

河南省药学会药物分析分会委员

邮箱：xuxia@zzu.edu.cn

个人简介

徐霞，博士，教授，美国加州大学访问学者，仪器仪表协会药物分析过程与控制协会主任委员，河南省药学会药物分析分会委员。

教学与教研

本科生：药物分析

硕士生：药物分析前沿，药物代谢，组学研究进展

科研项目

1）艾叶综合利用---艾叶提取物抗菌（病毒）系列产品的研制及机制研究

2）基于代谢组学技术的棉花类黄酮小分子生物合成途径的分析研究

3）一种载药织物的制备方法的优化

4）基于环介导等温扩增技术的肉类成分快速检测技术开发与应用

研究与成果

[1] Weiqi Cui, Hui Zhou, Jingxian Zhang, Junwei Zhang, Deqiao Wu, Ying Rong, Fanglin Liu, Junhui Liu, Haiyan Liu, Bo Wei, Youcai Tang, Xinglin Liao, Xia Xu. Hepatoprotective effect of Artemisia Argyi essential oil on bisphenol A-induced hepatotoxicity via inhibition of ferroptosis in mice [J]. Environmental Toxicology, 2023, 38(10): 2416-2428.

[2] Nan Zhang, Junwei Zhang, Weiqi Cui, Deqiao Wu, Jingxian Zhang, Bo Wei, Lingbo Qu, Xia Xu. Artemisia argyi H.Lév. & Vaniot essential oil induces ferroptosis in pancreatic cancer cells via up-regulation of TFR1 and depletion of γ- glutamyl cycle [J]. Fitoterapia, 2023, 168: 105522.

[3] Fanglin Liu; Ying Rong; Hui Zhou; Tong Yu; Luyao Liu; Qianwen Cao; Zhaolong Qin; Lingbo Qu; Xinglin Liao; Qiman Jiang; Nan Zhang; Xia Xu. Cineole inhibits the biosynthesis of leukotrienes and prostaglandins to alleviate allergic rhinitis: Insights from metabolomics [J]. Journal of pharmaceutical and biomedical analysis, 2023, 234: 115574.

[4] Hui Zhou, Ying Rong, Fanglin Liu, Tong Yu, Weiqi Cui, Qianwen Cao, Luyao Liu, Zhaolong Qin, Xiaoge Ma, Nan Zhang, Youcai Tang, Xia Xu. Insight gained via ultra-performance liquid chromatography tandem mass spectrometry-based metabolomics: Protective effect of Artemisia argyi H.Lév. & Vaniot essential oil on lipopolysaccharide-induced liver injury mice [J]. Biomedical chromatography: BMC, 2024, 1099-0801.

[5] Weijie Zhang, Lei Shi, Wei Zhou, Xin Liu, Yuan Xi, Xinyin Wang, Ya Li, Xia Xu. Oridonin impedes breast cancer growth by blocking cells in S phase and inhibiting the PI3K/AKT/mTOR signaling pathway [J]. Heliyon,2023, 9(7): e18046.

[6] Xuecui Yin, Lin Dong, Xiaohan Wang, Zhenzhen Qin, Yuying Ma, Xiaofei Ke, Ya Li, Qingde Wang, Yang Mi, Quanjun Lyu, Xia Xu, Pengyuan Zheng, Youcai Tang. Perilipin 5 regulates hepatic stellate cell activation and high-fat diet-induced non-alcoholic fatty liver disease [J]. Animal models and experimental medicine, 2023, 2576-2095.

[7] Fanglin Liu, Yongqiang Pang, Dexiang Liu, Qianwen Cao, Ying Rong, Xinglin Liao, Qiman Jiang. Peirong Xu, Di Chen, Xia Xu. Artemisia argyi essential oil as a green extraction solvent for in-syringe kapok fiber-supported liquid-phase microextraction and determination of triazole fungicide residues [J]. Microchemical Journal, 2024, 197: 109868.

实验室概况

棉花生物育种与综合利用全国重点实验室方向四棉籽营养成分挖掘与综合利用的主要成员。