1、基本情况
姓名:李小盟
籍贯:河南新乡
联系方式:xiaomeng.li@zzu.edu.cn
手机号(微信):150-3907-6741
TERMIS-AP(组织工程与再生医学国际学会-亚太)地区会议委员会委员,JMC-B等期刊最佳审稿人。
2、个人简历
教育经历
2014-09至2017-09,日本筑波大学/日本国立物质材料研究所,博士,导师:陈国平
2011-09至2014-06,华中科技大学,生物医学工程,硕士,导师:张胜民
2006-09至2010-06,郑州大学,材料科学与工程学院,高分子材料,学士,导师:黄霞
工作经历:
2018-01至今,郑州大学,力学与安全工程学院,郑州大学青年骨干教师,副教授,硕士生导师
2018-07至2021-10,郑州大学,力学与安全工程学院,博士后,导师:李倩
2010-07至2011-08,郑州宇通客车股份有限公司,技术工艺工程师。
3、研究领域
1)先进功能材料力学调控
2)医用水凝胶材料
3)力生物学与生物力学
欢迎力学、材料、生物医学工程、机械等相关专业学生报考研究生;
欢迎对科研感兴趣、学有余力的本科生参加双创项目等。
4、科研成果
主持或参加科研项目:
1) 仿生软骨细胞周基质的构建及其成分和硬度对MSC软骨分化的调控研究,国自然青年项目,主持,2020~2022(24万)
2) 可调控力学性能丝素基管状医疗器械的研发,青年人才企业创新团队,主持,2021(12万)
3) 不同力学特性水凝胶的制备及其对MSCs分化作用研究,中国博士后面上项目,主持,2018(5万+2.5万)
4) 仿生软骨周基质水凝胶的制备及其对软骨再生的作用研究,河南省科技攻关,主持,2020(10万)
5) 力学和血管化差异微环境对MSC软骨-骨分化调控机制研究,河南省干细胞医学联合实验室开放课题,主持,2022(3万)
6) 郑州大学拔尖博士启动支持项目,主持,2018(20万)
7) 可注射梯度硬度水凝胶促软骨-骨复合缺损再生机制研究,郑州大学,青年骨干教师,主持,2020
8) 脆弱青铜器功能保护材料研发与应用,国自然重点研发计划,第四,2020(185万)
9) 复合神经支架CS-HA/RES/hUMSCs 移植对TBI 的修复效果研究,国自然河南省联合基金,第三,2018(48万)
学术论文:
1) Trilayered biomimetic hydrogel scaffolds with dual-differential microenvironment for articular osteochondral defect repair, Materials Today Bio, 2024, 第一(中科院一区)
2) Dynamic Stiffening Hydrogel with Instructive Stiffening Timing Modulates Stem Cell Fate In Vitro and Enhances Bone Remodeling In Vivo, Advanced Healthcare Materials, 2023, 第一(中科院二区)
3) Erythrocyte membrane-camouflaged and double-factor sequential delivery nanocarriers postpone the progression of osteoarthritis, Chemical Engineering Journal, 2023, 通讯,(中科院一区)
4) An intrinsically non-flammable organic electrolyte for wide temperature range supercapacitors, Chemical Engineering Journal, 2023, 通讯(中科院一区)
5) Extracellular matrix mimicking dynamic interpenetrating network hydrogel for skin tissue engineering, Chemical Engineering Journal, 2023(中科院一区)
6) Solution-processed electronics for artificial synapses, Materials Horizons, 2021, 第一(中科院一区)
7) 3D Electrospun Nanofiber-Based Scaffolds: From Preparations and Properties to Tissue Regeneration Applications, Stem Cells International, 2021, 通讯,(中科院二区)
8) Enzyme-crosslinked electrospun fibrous gelatin hydrogel for potential soft tissue engineering, Polymers, 2020, 通讯,(中科院二区)
9) Functional hydrogels with tunable structures and properties for tissue engineering applications, Frontiers in Chemistry, 2018, 第一(中科院二区)
10) Influence of microporous gelatin hydrogels on chondrocyte functions, Journal of Materials Chemistry B, 2017, 第一 (中科院一区)
11) Fabrication of Highly Crosslinked Gelatin Hydrogel and Its Influence on Chondrocyte Proliferation and Phenotype, Polymers, 2017, 第一 (中科院二区)
12) 3D culture of chondrocytes in gelatin hydrogels with different stiffness, 2016, Polymers, 第一 (中科院二区)
13) Silk fibroin/poly (vinyl alcohol) blend scaffolds for controlled delivery of curcumin, 2015, Regenerative biomaterials, 第一(中科院二区)
14) Development of a silk fibroin/HTCC/PVA sponge for chronic wound dressing,2014, Journal of Bioactive and Compatible Polymers,第一(影响因子2.352)
15) Polymer-based dielectrics with high permittivity and low dielectric loss for flexible electronics, 2022, Journal of Materials Chemistry C (中科院二区)
16) Endothelial cell migration regulated by surface topography of poly (ε-caprolactone) nanofibers, 2021, ACS Biomaterials Science & Engineering (中科院二区)
17) Layer‐By‐Layer Printing Strategy for High‐Performance Flexible Electronic Devices with Low‐Temperature Catalyzed Solution‐Processed SiO2,2021, Small Methods (中科院一区)
18) Influence of viscosity on chondrogenic differentiation of mesenchymal stem cells during 3D culture in viscous gelatin solution-embedded hydrogels, 2021, Journal of Materials Science & Technology (中科院一区)
19) Preparation of PLGA-collagen hybrid scaffolds with controlled pore structures for cartilage tissue engineering, 2020, Progress in Natural Science: Materials International (中科院二区)
20) Electronic biopolymers: From molecular engineering to functional devices,2020, Chemical Engineering Journal (中科院一区)
21) Effect of particle size on the cellular uptake and anti-inflammatory activity of oral nanotherapeutics, 2020, Colloids and Surfaces B: Biointerfaces (中科院二区)
22) Promotion of endothelial cell adhesion and antithrombogenicity of polytetrafluoroethylene by chemical grafting of chondroitin sulfate, 2019, ACS Applied Bio Materials (影响因子2.536)
23) Programmed release of multimodal, cross-linked vascular endothelial growth factor and heparin layers on electrospun polycaprolactone vascular grafts,2019, ACS applied materials & interfaces (中科院一区)
24) Solution viscosity regulates chondrocyte proliferation and phenotype during 3D culture, 2019, Journal of Materials Chemistry B (中科院二区)
25) Induction of chondrogenic differentiation of human mesenchymal stem cells by biomimetic gold nanoparticles with tunable RGD density, 2017, Advanced Healthcare Materials(中科院一区)
26) Nanoencapsulation of individual mammalian cells with cytoprotective polymer shell, 2017, Biomaterials (中科院一区)
27) Single mammalian cell encapsulation by in situ polymerization, 2016, Journal of Materials Chemistry B (中科院一区)
专利:
1) 一种酶光双交联水凝胶的制备方法及采用酶光双交联水凝胶负载细胞的方法(发明专利,申请号:202110561292.6)
2) 架橋ゼラチンハイドロゲル及びその作製方法(日本发明专利,特许第7050296号)
3) 一种静电纺丝膜拉伸测试用固定装置(实用新型 已授权:ZL202020130600.0)
4) 一种组织工程材料及其制备方法 (发明专利,申请号:202211078490.8)