马达，郑州大学化学学院特聘教授、博士生导师，分子选控构筑与应用研究所所长。
联系方式：dama@fudan.edu.cn
通信地址：郑州市科学大道100号绿色催化研究中心302室
欢迎对超分子化学与医学/药学交叉研究感兴趣的硕士/博士研究生和博士后加入我们的课题组！
教育与工作经历：
2001.9-2005.7 北京大学，应用化学，学士;
2005.8-2010.9 马里兰大学（美国），有机化学，博士;
2010.10-2014.5北卡大学（美国），化学系，博士后研究员;
2014.6-2020.11复旦大学，化学系，研究员、博士生导师;
2020.12-现在 郑州大学，化学学院，特聘教授、博士生导师。
研究领域：
超分子化学
生物医学工程
科研项目：
2017-2020年，国家自然科学基金面上项目，基于新型开环葫芦脲衍生物的药物输送材料（21672042），主持。
2016-2018年，国家自然科学基金青年项目，基于柱芳烃的高分子药物输送载体（51503042），主持。
2020-2024年，国家自然科学基金创新群体项目，生物活性分子和超分子合成化学（21921003），参与。
代表性成果：
1.Da Ma, Gaya Hettiarachchi, Duc Nguyen, Ben Zhang, James B. Wittenberg, Peter Y. Zavalij, Volker Briken*, Lyle Isaacs*. Acyclic Cucurbit[n]uril Molecular Containers Enhance the Solubility and Bioactivity of Poorly Soluble Pharmaceuticals.Nature Chem.2012, 4, 503-510.
2.Da Ma, Stephanie Bettis, Kenneth Hanson, Maria Minakova, Leila Alibabaei, William Fondrie, Derek M. Ryan, Garegin A. Papoian, Thomas J. Meyer, Marcey L. Waters*, John M. Papanikolas*. Interfacial Energy Conversion in RuII Polypyridyl-Derivatized Oligoproline Assemblies on TiO2.J. Am. Chem. Soc.2013, 135, 5250-5253.
3.Da Ma, Ben Zhang, Ulrike Hoffmann, Martina Grosse Sundrup, Matthias Eikerman*, Lyle Isaacs*. Acyclic Cucurbit[n]uril-Type Molecular Containers Bind Neuromuscular Blocking Agents in Vitro and Reverse Neuromuscular Block in Vivo.Angew. Chem. Int. Ed.2012, 51, 11358-11362.
4. Dake Mao, Yajun Liang, Yamin Liu, Xianhao Zhou, Jiaqi Ma, Biao, Jiang, Jia Liu*,Da Ma*. Acid-Labile Acyclic Cucurbit[n]uril Molecular Containers for Controlled Release.Angew. Chem. Int. Ed.2017, 56, 12614~12618.
5. Shang Lan, Shuaijun Zhan, Jiaming Ding, Jiaqi Ma,Da Ma*. Pillar[n]arene-Based Porous Polymers for Rapid Pollutant Removal from Water.J. Mater. Chem. A, 2017, 5, 2514~2518.
6. Jiafu Chen, Yamin Liu, Dake Mao,Da Ma*. Acyclic Cucurbit[n]uril Conjugated Dextran for Drug Encapsulation and Bioimaging.Chem. Commun.2017, 53, 8739-8742.
7. Siyang Jiang, Shang Lan, Dake Mao, Xuan Yang, Kejia Shi,Da Ma*. Pro-Guest and Acyclic Cucurbit[n]uril Conjugated Polymers for the Controlled Release of Anti-Tumor Drugs.Chem. Commun.2018, 54, 9486-9489.
8. Yamin Liu, Yujun Liao, Pingtao Li, Zhan-Ting Li,Da Ma*. Crosslinked Pillar[6]arene Nanosponges Fabricated by Use of Supra-Amphiphilic Template: Cargo Encapsulation and Overcoming Multidrug Resistance.ACS Applied Mater. & Interfaces.2020, 12, 7974-7983.
9. Weipeng Mao, Yujun Liao,Da Ma*. A Supramolecular Assembly Mediated by Host-Guest Interaction for Improved Chemo-Photodynamic Combination Therapy.Chem. Commun.2020, 56，4192-4195.
10.Da Ma*. Enhancing endosomal escape for nanoparticle mediated siRNA delivery,Nanoscale2014, 6, 6415-6425.
11. Weipeng Mao, Dake Mao, Fan Yang,Da Ma*. Transformative Supramolecular Vesicles Based on Acid-Degradable Acyclic Cucurbit[n]uril and a Prodrug for Promoted Tumoral-Cell Uptake.Chem. Eur. J.2019, 25, 2272-2280.
12.Da Ma, Shaomin Tian, Jeremy Baryza, Christopher Luft, Joseph M. DeSimone*. Reductively Responsive Hydrogel Nanoparticles with Uniform Size, Shape, and Tunable Composition for Systemic siRNA Delivery in Vivo.Mol. Pharmaceutics2015, 12, 3518-3526.
13. Weipeng Mao, Shuaijun Zhan, Bowei Zhu,Da Ma*. Step-Growth Cyclo-Oligomerization for the Preparation of Di- and Tetrafunctionalized Pillar[5]arenes.J. Org. Chem.2018, 83, 4147-4152.
14. Shang Lan, Yamin Liu, Kejia Shi,Da Ma*. Acetal-Functionalized Pillar[5]arene: A pH-Responsive and Versatile Nanomaterial for the Delivery of Chemotherapeutic Agents.ACS Appl. Bio Mater.2020, 3, 2325-2333.
15.Da Ma, Zuzana Gargulakova, Peter Y. Zavalij, Vladimir Sindelar*, Lyle Isaacs*. Reasons Why Aldehydes Do Not Generally Participate in Cucurbit[n]uril Forming Reactions.J. Org. Chem.2010, 75, 2934-2941.
16.Da Ma, Peter Y. Zavalij, Lyle Isaacs*. Acyclic Cucurbit[n]uril Congeners Are High Affinity Hosts.J. Org. Chem.2010, 75, 4786-4795.
17. Shang Lan, Xuan Yang, Kejia Shi, Rong Fan,Da Ma*. Pillarquinone-Based Porous Polymer for a Highly-Efficient Heterogeneous Organometallic Catalysis.ChemCatChem2019, 11, 2864-2869.
18. Yamin Liu, Kejia Shi,Da Ma*. Water-Soluble Pillar[n]arene Mediated Supramolecular Self-Assembly: Multi-Dimensional Morphology Controlled by Host Size.Chem. Asian J.2019, 14, 307-312.
19. Jiaming Ding, Jiafu Chen, Weipeng Mao, Junrou Huang,Da Ma*. A New Synthetic Method for Non-Symmetric Pillar[5]arenes with Simple Isolation and Improved Yield.Org. & Biomol. Chem.2017, 15, 7894~7897.
20. Yamin Liu, Fang Zhou, Fan Yang,Da Ma*. Carboxylated Pillar[n]arene (n = 5-7) Host Molecules: High Affinity and Selective Binding in Water.Org. Biomol. Chem.2019, 17, 5106-5111.
21. Xuan Yang, Weipeng Mao, Yamin Liu, Libai Li,Da Ma*. Supramolecular Vesicles Based on Water-Soluble 2,6-Helic[6]arene: High Affinity Binding, Stimuli Responsiveness and Delivery of Doxorubicin to Cancer Cells.Chin. J. Chem.2019, 37, 575-580.
22.Da Ma,Raymond Glassenberg, Soumyadip Ghosh, Peter Y. Zavalij, Lyle Isaacs*, Acyclic Cucurbituril Congener Binds to Local Anaesthetics,Supramol. Chem.2012, 24, 325-332.
23. Weipeng Mao, Xuan Yang,Da Ma*.ChemNanoMat.2020, 6, 118-123.
24. Yamin Liu, Xi Chen, Jiaming Ding, Lin Yu*,Da Ma*, Jiandong Ding. Improved Solubility and Bioactivity of Camptothecin Family Antitumor Drugs with Supramolecular Encapsulation by Water Soluble Pillar[6]arene.ACS Omega2017, 2, 5283~5288.
