专 业：分析化学
学 历：博士研究生
出生年月：1983.04
职称：副教授
性 别：男
E-mail：jiage@zzu.edu.cn
研究方向
生物化学分析新方法研究与应用•肿瘤细胞MicroRNA原位成像与检测研究•二维纳米材料研究与应用
工作和学习经历
◆2014/11-至今，校聘副教授，硕士生导师，郑州大学化学学院。
◆2017/05-2018/05，访问学者，美国佛罗里达大学，导师：谭蔚泓
◆2009/09-2014/07，分析化学博士，湖南大学化学化工学院,化学生物传感与计量学国家重点实验室，导师：俞汝勤院士。
◆2004/09-2008/07，分析化学硕士，湖南大学化学化工学院,化学生物传感与计量学国家重点实验室，导师：王柯敏教授。
◆2000/09-2004/06，化学学士，湖南大学化学化工学院。
主持科研项目：
1. 国家自然科学基金青年项目，基于单层WS2纳米片的新型核酸传感技术及其microRNA检测应用研究，2016/01-2018/12，20万元，已结题，主持。
2. 化学生物传感与计量学国家重点实验室（湖南大学）开放课题，基于核酸分子模板的金属纳米团簇合成及其新型荧光传感器的研究，2015/03-2017/3, 3万元，已结题，主持。
科研成果
1:Jia Ge, En-Cai Ou, Ru-Qin Yu and Xia Chu.A novel aptameric nanobiosensor based onself-assembledDNA-MoS2nanosheetarchitecturefor biomolecule detection.Journal of Materials Chemistry B, 2014, 2(6): 625-628.
2:Jia Ge, Liang-Liang Zhang, Si-Jia Liu, Ru-Qin Yu, and Xia Chu. A highly sensitive target-primed rolling circle amplification (TPRCA) method for fluorescent in situ hybridization detection of microRNA in tumor cells.Analytical Chemistry, 2014, 86(3): 1808-1815.
3: Jia Ge, Li-Juan Tang, Qiang Xi, Xi-Ping Li, Ru-Qin Yu, Jian-Hui Jiang, and Xia Chu. A WS2nanosheet based sensing platform for highly sensitive detection of T4 polynucleotide kinase and its inhibitors.Nanoscale,2014,6(12): 6866-6872.
4:Jia Ge, Xi-Ping Li, Jian-Hui Jiang and Ru-Qin Yu. A highly sensitive label-free sensor for Mercury ion (Hg2+) by inhibiting thioflavin T as DNA G-quadruplexes fluorescent inducer.Talanta,2014, 122: 85-90.
5:Jia Ge, Zhi-Mei Huang, Qiang Xi, Ru-Qin Yu and Jian-Hui Jiang.A novel amplified fluorescent strategy by hybridization chain reaction for highly sensitive detection of biothiols based on graphene oxide nanosheets.Chemical Communication，2014,50(80): 11879-11882.
6：Lin Zhang, Qi-Yong Cai, Jie Li,Jia Ge*, Jun-Yan Wang, Zhen-Zhen Dong, Zhao-Hui Li*, A label-free method for detecting biothiols based on poly(thymine)-templated copper nanoparticles,Biosensors and Bioelectronics, 2015, 69:77-82.
7:Zheng-Zhen Dong, Lin Zhang, Min Qiao,Jia Ge*, Ai-Ling Liu, Zhao-Hui Li*, A label-free assay for T4 polynucleotide kinase/phosphatase activity and its inhibitors based on poly(thymine)-templated copper nanoparticles,Talanta, 2016, 146, 253-258.
8:Jia Ge*, Lin Zhang, Zheng-Zhen Dong, Qi-Yong Cai, Zhao-Hui Li*, Sensitive and label-free T4 polynucleotide kinase/phosphatase detection based on poly(thymine)-templated copper nanoparticles coupled with nicking enzyme-assisted signal amplification,Analytical Methods, 2016, 8, 2831-2836.
9: Jia Ge*, Zheng-Zhen Dong, Lin Zhang, Qi-Yong Cai, Dong-Mei Bai, Zhao-Hui Li*, Label-free biosensor based on dsDNA-templated copper nanoparticles for highly sensitive and selective detection of NAD+,RSC Advances, 2016, 6, 91077-91082.
10:Sai-Sai Zhou, Lin Zhang, Qi-Yong Cai, Zheng-Zhen Dong, Xin Geng,Jia Ge*, Zhao-Hui Li*, A facile label-free aptasensor for detecting ATP based on fluorescence enhancement of poly(thymine)-templated copper nanoparticles,Analytical and Bioanalytical Chemistry, 2016, 408, 6711-6717.
11: Jia Ge*, Xin-Geng, Ya-Hui Du, Jia-Jia Chen, Lin Zhang, Dong-Mei Bai, Dan-Yang Ji, Ya-Lei Hu, Zhao-Hui Li. Highly sensitive fluorescence detection of mercury (II) ions based on WS2nanosheets and T7 exonuclease assisted cyclic enzymatic amplification.Sensors and Actuators B-Chemical, 2017, 249: 189-194.
12: Dong-Mei Bai, Dan-Yang Ji, Jin-Hua Shang, Ya-Lei Hu, Jia Gao, Lin Zhang,Jia Ge*, Zhao-Hui Li. A rapid biosensor for highly sensitive protein detection based on G-quadruplex-Thioflavin T complex and terminal protection of smallmolecule-linked DNA.Sensors and Actuators B-Chemical, 2017, 252, 1146-1152.
13:Jia Ge*, Ren Cai, Lu Yang, Liangliang Zhang, Ying Jiang, Yu Yang, Cheng Cui, Shuo Wan, Xia Chu, Weihong Tan. Core-shell HA-AuNPs@SiNPs nanoprobe for sensitive fluorescence hyaluronidase detection and cell imaging.ACS Sustainable Chemistry & Engineering, 2018, 6(12): 16555-16562.
14: Jia Ge*, Ke Xing, Xin Geng, Ya-Lei Hu, Xue-Ping Shen, Lin Zhang, Zhao-Hui Li. Human serum albumin templated MnO2nanosheets are oxidase mimics for colorimetric determination of H2O2and for enzymatic determination of glucose.Microchimica Acta, 2018, 185, 559.
15:Jia Ge*, Dong-Mei Bai, Xin Geng, Ya-Lei Hu, Qi-Yong Cai, Ke Xing, Lin Zhang, Zhao-Hui Li. Fluorometric determination of nucleic acids based on the use of polydopamine nanotubes and target-induced strand displacement amplification.Microchimica Acta, 2018, 185, 105.
16:Jia Ge*, Ren Cai, Xigao Chen, Qiong Wu, Liangliang Zhang, Ying Jiang, Cheng Cui, Shuo Wan, Weihong Tan. Facile approach to prepare HSA-templated MnO2nanosheets as oxidase mimic for colorimetric detection of glutathione.Talanta, 2018, 195, 40-45.
17:Ya-Lei Hu, Xin Geng, Lin Zhang, Zhong-Ming Huang,Jia Ge*, Zhao-Hui Li. Nitrogen-doped carbon dots mediated fluorescent on-off assay for rapid and highly sensitive pyrophosphate and alkaline phosphatase detection.Scientific Reports, 2017, 7: 5849.
