孟红敏，女，博士，副教授,中共党员,郑州大学“青年拔尖人才”，硕士生导师
出生年月：1988. 12
籍贯：河南开封
邮箱：hmmeng2017@zzu.edu.cn
学习及工作经历：
1．2017年6月—至今，郑州大学，化学学院，生命分析化学研究所副教授
2. ?2015年7月—2017年5月，河南师范大学，化学化工学院，讲师
3．2010年9月—2015年6月，湖南大学，化学化工学院，理学博士(导师：谭蔚泓院士，张晓兵教授)
4．2006年9月—2010年6月，湖南大学，化学学院，学士
研究领域：核酸荧光纳米探针
主持项目：
1. 国家自然科学基金青年科学基金项目：基于核酸适体-MOFs的双光子荧光纳米探针的构建及其生物分析应用研究，21605038，2017.01 - 2019.12，主持，已结题。
2. 河南省科技攻关：基于功能核酸的液体活检技术用于食管癌标志物的可视化分析及试剂盒的开发，2021.1 - 2022.12，主持，在研。
3. 河南省高等学校重点科研项目，主持，已结题。
4. 郑州大学“青年拔尖人才”科研专项，主持，在研。
代表性论文
2020年度
1. Xinxin Shi,Hong-Min Meng*, Xin Geng, Lingbo Qu, and Zhaohui Li*，DNAzyme–Metal–Organic Framework Two-Photon Nanoprobe for In situ Monitoring of Apoptosis-Associated Zn2+in Living Cells and Tissues, ACS Sensors, 2020 5 (10), 3150-3157
2. Hong-Min Meng, Xinxin Shi (Joint first author), Juan Chen, Yuhui Gao, Lingbo Qu, Ke Zhang, Xiao-Bing Zhang,* and Zhaohui Li,* DNA Amplifier-Functionalized Metal-Organic Frameworks for Multiplexed Detection and Imaging of Intracellular mRNA, ACS Sensors, 2020,5(1):103-109.
3. Yanan Wu,Hong-Min Meng,*Juan Chen, Kemei Jiang, Ran Yang, Yingying Li, Ke Zhang, Lingbo Qu,* Xiao-Bing Zhang, and Zhaohui Li,* Accelerated DNAzyme-based fluorescent nanoprobe for highly sensitive microRNA detection in live cells,Chemical Communications, 2020, 56 (3): 470-473.
4. Mengyi Xiong, Meng Zhang, Qin Liu, Chan Yang, Qingji Xie, Guoliang Ke,*Hong-Min Meng,* Xiao-Bing Zhang,* and Weihong Tan, Biomineralized nanoparticles enable an enzymeassisted DNA signal amplification in living cells,Chemical Communications,2020,56(19): 2901-2904.
5. Juan Chen, Jinlu Tang,Hong-Min Meng,* Zhuo Liu, Lin Wang, Xin Geng, Yanan Wu, Ling-Bo Qu and Zhaohui Li*, Recognition triggered assembly of split aptamers to initiate a hybridization chain reaction for wash-free and amplified detection of exosomes,Chemical Communications,2020,56(63): 9024-9027.
6. Chengzhen Hu, Kemei Jiang, Zihao Shao, Minqing Shi andHong-Min Meng *, A DNAzyme-based label-free fluorescent probe for guanosine-5’-triphosphate detection, Analyst, 2020, 145, 6948–6954.
7. Xinxin Shi, Yalei Hu,Hong-Min Meng*, Jie Yang, Lingbo Qu, Xiao-Bing Zhang, Zhaohui Li,* Red emissive carbon dots with dual targetability for imaging polarity in living cells, Sensors and Actuators B: Chemical, 2020, 306, 127582
8. Juan Chen,Hong-Min Meng,*Ying An, Xin Geng, Keran Zhao, Lingbo Qu, Zhaohui Li,* Structure-switching aptamer triggering hybridization displacement reaction for label-free detection of exosomes, Talanta, 2020, 209, 120510
9. Juan Chen,Hong-Min Meng*, & Ying An, Juanzu Liu, Ran Yang, Lingbo Qu and Zhaohui Li*, A fluorescent nanosphere-based immunochromatography test strip for ultrasensitive and point-of-care detection of tetanus antibody in human serum, Analytical and Bioanalytical Chemistry, 2020, 412, 1151–1158.
10. Yufei Wang,Hong-Min Meng,* Guosheng Song, Zhaohui Li, and Xiao-Bing Zhang*, Conjugated-Polymer-Based Nanomaterials for Photothermal Therapy, ACS Applied Polymer Materails, 2020, 2, 4258?4272
11. Kemei Jiang, Yanan Wu, Juan Chen, Mingqing Shi,Hong-Min Meng*, Zhaohui Li*, Molecular recognition triggered aptazyme cascade for ultrasensitive detection of exosomes in clinical serum samples, Chinese Chemical Letters, 2020, doi.org/10.1016/j.cclet.2020.11.031.
2019年度
12. Di Zhao, Hongmin Meng*, & Ming-Qing Shi, Na Li and Guo-Jiang Mao*, Two-photon excited fluorescent silica nanoparticles loaded with iron(II) as a probe for determination and imaging of hydrogen peroxide in living cells, Microchimica Acta (2019) 186:805
13. Junyan Wang,Hong-Min Meng,* Juan Chen, Juanzu Liu, Lin Zhang,* Lingbo Qu, Zhaohui Li,* and Yuehe Lin, Quantum Dot-Based Lateral Flow Test Strips for Highly Sensitive Detection of the Tetanus Antibody, ACS Omega 2019, 4, 6789?6795
2018年度
14. Hong-Min Meng, * Di Zhao, Na Lia and Junbiao Chang*. A graphene quantum dot-based multifunctional two-photon nanoprobe for the detection and imaging of intracellular glutathione and enhanced photodynamic therapy, Analyst, 2018, 143, 4967-4973
15. Hong-Min Meng, Xiao-Xiao Hu, Ge-Zhi Kong, Chan Yang, Ting Fu, Zhao-Hui Li,* Xiao-Bing Zhang*. Aptamer-functionalized nanoscale metal-organic frameworks for targeted photodynamic therapy, Theranostics, 2018, 8, 4322-4344.
2016年度
16.Hong-Min Meng, Hui Liu, Hailan Kuai, Ruizi Peng, Liuting Mo and Xiao-Bing Zhang*. Aptamer-integrated DNA Nanostructures for Biosensing, Bioimaging and Cancer Therapy, Chemical Society Reviews 2016, 45(9): 2583-2602.
17.Hong-Min Meng, Xiao-Bing Zhang*, Chan Yang, Hailan Kuai, Guo-Jiang Mao, Liang Gong, Wenhan Zhang, Suling Feng, Junbiao Chang*. Efficient Two-Photon Fluorescence Nanoprobe for Turn-On Detection and Imaging of Ascorbic Acid in Living Cells and Tissues, Analytical Chemistry 2016, 88, 6057-6063.
博士期间论文
18.Hong-Min Meng, Xiaobing Zhang*, Yifan Lv, Zilong Zhao, Nan-Nan Wang, Ting Fu, Huanhuan Fan, Hao Liang, Liping Qiu, Guizhi Zhu, and Weihong Tan*. DNA Dendrimer: An Efficient Nanocarrier of Functional Nucleic Acids for Intracellular Molecular Sensing. ACS Nano 2014, 8, 6171-6181.
19.Hong-Min Meng, Ting Fu, Xiao-Bing Zhang*, Nan-Nan Wang, Weihong Tan*, Guo-Li Shen, and Ru-Qin Yu. Efficient Fluorescence Turn-On Probe for Zirconium via a Target-Triggered DNA Molecular Beacon Strategy. Analytical Chemistry 2012, 84, 2124-2128.
20. Hong-Min Meng, Zhen Jin, Yifan Lv, Chan Yang, Xiaobing Zhang*, Weihong Tan, and Ruqin Yu. Activatable Two-Photon Fluorescence Nanoprobe for Bioimaging of Glutathione in Living Cells and Tissues. Analytical Chemistry 2014, 86, 12321-12326.
21.Hong-Min Meng, Limin Lu, Xu-Hua Zhao, Zhuo Chen*, Zilong Zhao, Chan Yang, Xiao-Bing Zhang*, and Weihong Tan. Multiple Functional Nanoprobe for Contrast-Enhanced Bimodal Cellular Imaging and Targeted Therapy. Analytical Chemistry 2015, 87, 4448-4454.
22.Hong-Min Meng, Ting Fu, Xiao-Bing Zhang and Weihong Tan*. Cell-SELEX-based aptamer-conjugated nanomaterials for cancer diagnosis and therapy. National Science Review 2015, 2, 71-84.
