赵雪梅，博士，副教授，硕士生导师。

邮箱：zxm@zzu.edu.cn

电话：13503821781

地址：郑州市科学大道100号郑州大学化学与分子工程学院450001

教育背景

1991，郑州大学，化学与分子工程学院（原化学系），学士学位

1994，郑州大学，化学与分子工程学院（原化学系），硕士学位

2006，郑州大学，化学与分子工程学院（原化学系），博士学位

工作履历

1994-迄今，郑州大学，化学学院，副教授

研究领域

有机合成方法学。利用金属催化生成C-C键，C-杂键的反应是构筑有机化合物的经典而高效的方法之一，是目前化学界研究的热点。利用过渡金属有机化合物，高效，简便地实现各种官能团的相互转变，力求在反应中实现原子经济性和绿色合成思路，是目前的社会大环境对化学工作者的要求。利用过渡金属有机化合物作催化剂，使惰性的C-H键实现各种官能团的转化，在资源日益匮乏的今天，是新世纪有机化学需要实现的基本社会任务。

研究成果

一，科研项目

1.含M-C键的三齿配位钯和铂化合物的合成与应用研究（国家自然科学基金20872133）

2.过度金属催化的碳-碳键、碳-杂原子键生成反应研究（国家自然科学基金20472047）

3.二茂铁基环金属化合物的合成、性能及其在催化反应中的应用(高等学校博士学科点专项科研基金20040459008）

4.二茂铁基氨基酸、嘌呤亚胺衍生物环金属化的研究（河南省自然科学基金0411020200）

5.郑州大学研究生教育支持基金,多项，主持

6. 2019年度河南省高等教育教学改革研究与实践项目，参与

二、论文论著与专利

(1) Jian-Feng Suo,Xue-Mei Zhao, Kai-Xin Zhang, Sheng-Li Zhou, Jun-Long Niu, Mao-Ping Song, “Cobalt-catalyzed perfluoroalkylation of quinoline amides at the C5 position”,Synthesis2017,49, 3916-3924.

(2)朱新举，卢帅，杨发琉，郭玉静，田子瑶，郝新奇，赵雪梅，宋毛平, “2-苯基-3-（甲苯磺甲基）咪唑并（1.2-a）吡啶类化合物及其合成方法”，2017.08.25,中国，CN201610671844.8（专利）

(3)郝新奇，庞伟，菅宁歌，赵雪梅，牛俊龙，龚军芳，宋毛平，”一种手性咪唑硫配体及其合成方法”，2017.02.15,中国，CN201410333636.8（专利）

(4)郝新奇，菅宁歌，高翔，申晓静，祝智慧，朱新举，赵雪梅，宋毛平，”基于苯取代氟硼二吡咯及二苯胺基芴的双光子荧光染料及其合成方法”，2017, 03, 08,中国，CN201610889055.1（专利）

(5)Shuai Lu, Xinju Zhu, Ke Li, Yu-Jing Guo, Meng-Dan Wang,Xue-Mei Zhao, Xin-Qi Hao, Mao-Ping Song, “Reactivity of p‑Toluenesulfonylmethyl Isocyanide: Iron-Involved C−H Tosylmethylation of Imidazopyridines in Nontoxic Media”,J. Org. Chem.2016,81, 8370-8377.

(6) Xin-Xiang Zheng, Cong Du,Xue-Mei Zhao, Xinju Zhu, Jian-Feng Suo, Xin-Qi Hao, Jun-Long Niu*, and Mao-Ping Song*, “Ni(II)-Catalyzed C(sp2)–H Alkynylation/Annulation with Terminal Alkynes under an Oxygen Atmosphere: A One-Pot Approach to 3-Methyleneisoindolin-1-one”,J. Org. Chem.,2016,81, 4002–4011.

(7)Ke Li,Xue-Mei Zhao, Fa-Liu Yang, Xiao-Han Hou, Yan Xu, Yan-Chun Guo, Xin-Qi Hao, Mao-Ping Song, “Catalyst-free Friedel–Crafts hydroxyalkylation of imidazo[1,2-α]pyridines with ethyl trifluoropyruvate”, RSC Adv.2015,5, 90478-90481.

(8) Shou-Kun Zhang, Xin-Yan Yang,Xue-Mei Zhao, Peng-Xiang Li, Jun-Long Niu, Mao-Ping Song, “Palladium-Catalyzed Selective β-Arylation of Aliphatic Amides Using a Removable N,O-Bidentate Auxiliary”,Organometallics2015,34, 4331-4339.

(9) Xin-Qi Hao, Ya-Nan Dong, Biao Gao, Ke Li,Xue-Mei Zhao, Yan Xu, Mao-Ping Song, “Biimidazoline ligands for palladium-catalyzed asymmetric allylic alkylation”,Tetrahedron: Asymmetry2015,26, 1360-1368.

(10)Xue-Mei Zhao, Xin-Qi Hao, Kun-Lun Wang, Jun-Rui Liu, Mao-Ping Song*, Yang-Jie Wu, “Catalysis of the Suzuki–Miyaura coupling reaction in water by heteroannular cyclopalladated ferrocenylimine complexes”,Transition Met. Chem.2009,34, 683-688.

(11)赵雪梅，赵海沨，牛俊龙，宋毛平*，吴养洁, “碘取代含杂环的二茂铁亚胺异环环钯化合物的合成及晶体结构”,化学通报，2008，71，281-284.

(12)赵雪梅，赵海沨，牛俊龙，宋毛平*，吴养洁, “含杂环二茂铁亚胺异环环钯化合物在Heck反应中的催化活性研究”,化学研究与应用，2008，20，260-264.

(13)Xue-Mei Zhao, Xin-Qi Hao, Bin Liu, Mao Lin Zhang, Mao-Ping Song, Yangjie Wu, “Syntheses and structural characterization of novel heteroannular cyclopalladated ferrocenylimine”,J. Organomet. Chem.2006,691, 255-260.

(14)Xue-Mei Zhao, Xin-Qi Hao, Liu Bin, Maolin Zhang, Mao-Ping Song, Yangjie Wu, “Synthesis and Structures of New Cyclopalladated Ferrocenylimines”,Chin. Chem. Lett.2006, 3, 317-320.

(15)赵雪梅，郝新奇，刘斌，朱玉，宋毛平，吴养洁，”N-取代苄基-2-氯化汞基芳胺的金属交换反应”，化学研究，2006，17，5-8.

(16)赵雪梅，郝新奇，刘伟，张茂林，宋毛平，吴养洁，N-二茂铁甲基乙酰胺的合成及其晶体结构，化学研究与应用，2005，17，725-728.

(17).浅谈医用有机化学的教学体

(13)Xue-Mei Zhao, Xin-Qi Hao, Bin Liu, Mao Lin Zhang, Mao-Ping Song, Yangjie Wu, “Syntheses and structural characterization of novel heteroannular cyclopalladated ferrocenylimine”,J. Organomet. Chem.2006,691, 255-260.

(14)Xue-Mei Zhao, Xin-Qi Hao, Liu Bin, Maolin Zhang, Mao-Ping Song, Yangjie Wu, “Synthesis and Structures of New Cyclopalladated Ferrocenylimines”,Chin. Chem. Lett.2006, 3, 317-320.

(15)赵雪梅，郝新奇，刘斌，朱玉，宋毛平，吴养洁，”N-取代苄基-2-氯化汞基芳胺的金属交换反应”，化学研究，2006，17，5-8.

(16)赵雪梅，郝新奇，刘伟，张茂林，宋毛平，吴养洁，N-二茂铁甲基乙酰胺的合成及其晶体结构，化学研究与应用，2005，17，725-728.

奖励与荣誉

1.Syntheses and structural characterizaion of novel Heteroanaularcyclopalladated ferrocenylimine

河南省第十届自然科学优秀学术论文奖，二等奖

2.Syntheses and structures of New cyclopalladated ferrocenylimines

河南省第十届自然科学优秀学术论文奖，二等奖

3.Catalysis of the Suzuki-Miyayra coupling reaction in water by heteroannular cyclopalladated ferrocenylimine complex

河南省首届自然科学学术奖-河南省自然科学优秀学术论文奖，二等奖

Curriculum vitae（除标题项目外其他信息均应修改）

Profile（个人简介）

Xue-Mei Zhao，PhD，Associate professor

Email：zxm@zzu.edu.cn

Address:College of Chemistry and Molecular Engineering, Zhengzhou University, KeXue Avenue 100, Zhengzhou 450001

Educational（教育背景）

1991, Zhengzhou University, College of Chemistry and Molecular Engineering (Department of Chemistry), B. S. in Chemistry

1994, Zhengzhou University, College of Chemistry and Molecular Engineering (Department of Chemistry), M. S. in Organic Chemistry

2006, Zhengzhou University, College of Chemistry and Molecular Engineering (Department of Chemistry), PhD in Organic Chemistry

Experience（工作经历）

1994-present, College of Chemistry and Molecular Engineering, Zhengzhou University, Associate professor

Research area（研究领域）

Organic synthesis methodology

Selected publications（研究成果）

(1) Jian-Feng Suo,Xue-Mei Zhao, Kai-Xin Zhang, Sheng-Li Zhou, Jun-Long Niu, Mao-Ping Song, “Cobalt-catalyzed perfluoroalkylation of quinoline amides at the C5 position”, Synthesis 2017, 49, 3916-3924

(2)Shuai Lu, Xinju Zhu, Ke Li, Yu-Jing Guo, Meng-Dan Wang,Xue-Mei Zhao, Xin-Qi Hao, Mao-Ping Song, “Reactivity of p‑Toluenesulfonylmethyl Isocyanide: Iron-Involved C−H Tosylmethylation of Imidazopyridines in Nontoxic Media”,J. Org. Chem.2016,81, 8370-8377.

(3) Xin-Xiang Zheng, Cong Du,Xue-Mei Zhao, Xinju Zhu, Jian-Feng Suo, Xin-Qi Hao, Jun-Long Niu*, and Mao-Ping Song*, “Ni(II)-Catalyzed C(sp2)–H Alkynylation/Annulation with Terminal Alkynes under an Oxygen Atmosphere: A One-Pot Approach to 3-Methyleneisoindolin-1-one”,J. Org. Chem.,2016,81, 4002–4011.

(4)Ke Li,Xue-Mei Zhao, Fa-Liu Yang, Xiao-Han Hou, Yan Xu, Yan-Chun Guo, Xin-Qi Hao, Mao-Ping Song, “Catalyst-free Friedel–Crafts hydroxyalkylation of imidazo[1,2-α]pyridines with ethyl trifluoropyruvate”, RSC Adv.2015,5, 90478-90481.

(5) Shou-Kun Zhang, Xin-Yan Yang,Xue-Mei Zhao, Peng-Xiang Li, Jun-Long Niu, Mao-Ping Song, “Palladium-Catalyzed Selective β-Arylation of Aliphatic Amides Using a Removable N,O-Bidentate Auxiliary”,Organometallics2015,34, 4331-4339.

(6) Xin-Qi Hao, Ya-Nan Dong, Biao Gao, Ke Li,Xue-Mei Zhao, Yan Xu, Mao-Ping Song, “Biimidazoline ligands for palladium-catalyzed asymmetric allylic alkylation”,Tetrahedron: Asymmetry2015,26, 1360-1368.

(7)Xue-Mei Zhao, Xin-Qi Hao, Kun-Lun Wang, Jun-Rui Liu, Mao-Ping Song*, Yang-Jie Wu, “Catalysis of the Suzuki–Miyaura coupling reaction in water by heteroannular cyclopalladated ferrocenylimine complexes”,Transition Met. Chem.2009,34, 683-688.

(8)Xue-Mei Zhao, Xin-Qi Hao, Bin Liu, Mao Lin Zhang, Mao-Ping Song, Yangjie Wu, “Syntheses and structural characterization of novel heteroannular cyclopalladated ferrocenylimine”,J. Organomet. Chem.2006,691, 255-260.

(9)Xue-Mei Zhao, Xin-Qi Hao, Liu Bin, Maolin Zhang, Mao-Ping Song, Yangjie Wu, “Synthesis and Structures of New Cyclopalladated Ferrocenylimines”,Chin. Chem. Lett.2006, 3, 317-320.

Selected honors/awards（奖励与荣誉）