邹大鹏

作者: 时间:2021-01-21 点击数:

zdp-2

邹大鹏,教授

通讯地址:郑州市大学北路75号,郑州大学化学学院

办公电话:+86-371-67766865

邮箱:zdp@zzu.edu.cn

教育背景

09/2001-07/2004,郑州大学化学系,理学博士

09/1988-07/1991,郑州大学化学系,理学硕士

09/1984-07/1988,郑州大学化学系,理学学士

工作经历

11/2008-至今,郑州大学化学学院,教授

01/2006-01/2008,瑞典皇家理工学院,博士后

09/2004-09/2005,日本国立医药品食品卫生研究所,访问学者

11/1999-10/2008,郑州大学化学系,副教授

11/1994-10/1999,郑州大学分析测试中心,讲师

07/1991-10/1994,郑州大学分析测试中心,助教

研究方向

开展具有绿色、经济、高效的化学合成新方法研究。主要包括:1、过渡金属催化的C-H键官能团化、碳-碳、碳-氮、碳-氧偶联等反应方法学研究。2、研究在有机化合物中选择性引入氟原子和含氟片段的新策略,合成功能化的有机氟化合物。3、有机硼试剂的合成方法及功能化转化研究。

承担科研项目

1. 2011. 1-2013.12 “河南辅仁医药科技开发有限公司创新药物孵化基地建设”,国家科技部,“重大新药创制”科技重大专项,编号2011ZX09401-004

2. 2012.1-2013.12 “瓜环与咪唑类衍生物的超分子自组装及其催化性能研究”,河南省科技厅,河南省基础与前沿技术研究计划资助项目,编号122300413203

部分代表论文

1. Nickel-promoted C(2)-H amidation of quinoline N-oxides with N-fluorobenzenesulfonimide,Han, Shuaijun; Gao, Xianying; Wu, Qingsong; Li, Jingya;Zou, Dapeng*; Wu, Yusheng*; Wu, Yangjie*,Org. Chem. Front.,2019,6(6), 830-834.

2. Transition-Metal-Free Direct Trifluoromethylation and Perfluoroalkylation of Imidazopyridines under Mild Conditions,Han, Shuaijun; Gao, Xianying; Wu, Qingsong; Li, Jingya;Zou, Dapeng*; Wu, Yangjie*; Wu, Yusheng*,Adv. Syn. & Catal.,2019,361(7), 1559-1563.

3. Transition-Metal-Free Oxidation of Benzylic C-H Bonds of Six-Membered N-Heteroaromatic Compounds,Gao, Xianying; Han, Shuaijun; Zheng, Maolin; Liang, Apeng; Li, Jingya;Zou, Dapeng*; Wu, Yusheng*; Wu, Yangjie*,J. Org. Chem,2019,84(7), 4040-4049.

4. Pd-Catalyzed Alkylation of (Iso)quinolines and Arenes: 2-Acylpyridine Compounds as Alkylation Reagents, Wu, Qingsong; Han, Shuaijun; Ren, Xiaoxiao; Lu, Hongtao; Li, Jingya;Zou, Dapeng*; Wu, Yangjie*; Wu, Yusheng*,Org. Lett.,2018,20(20), 6345-6348.

5. Nickel-Catalyzed Direct C-H Trifluoromethylation of Free Anilines with Togni's Reagent. Gao, Xianying; Geng, Yang; Han, Shuaijun; Liang, Apeng; Li, Jingya; Zou, Dapeng*; Wu, Yusheng*; Wu, Yangjie*.Org. Lett.,2018,20(13), 3732-3735.

6. Palladium-Catalyzed Decarboxylative Cross-Couplings of 1-Boc-3-iodoazetidine: Regioselective Access to 2-Alkynylazetidines, 3-Alkynylazetidines and 3-Vinylazetidines.Han, Shuaijun; Ren, Xiaoxiao; Wu, Qingsong; Liang, Apeng; Li, Jingya; Zou, Dapeng*; Wu, Yangjie*; Wu, Yusheng*.Adv. Syn. & catal.2018,360(12), 2308-2312.

7. Palladium-Catalyzed Diastereoselective Synthesis of 3-Arylbutanoic Acid Derivatives. Zhi, Wubin; Li, Jingya;Zou, Dapeng*; Wu, Yusheng*; Wu, Yangjie*.J. Org. Chem.2017,82(23), 12286-12293.

8. CuI-Catalyzed Fluorodesulfurization for the Synthesis of Monofluoromethyl Aryl Ethers. Geng, Yang; Liang, Apeng; Gao, Xianying; Niu, Chengshan; Li, Jingya; Zou, Dapeng*; Wu, Yusheng*; Wu, Yangjie*.J. Org. Chem.2017,82, 8604-8610.

9. Ligand-Controlled Palladium-Catalyzed Pyridylation of 1-tert-Butoxycarbonyl-3-iodoazetidine:Regioselective Synthesis of 2- and 3-Heteroarylazetidines. Zhang, Yudan; Geng, Zhiyue; Li, Jingya; Zou, Dapeng*; Wu, Yangjie*; Wu, Yusheng*.Adv. Syn. & catal.2017,359(3), 390-394.

10. Regioselective Synthesis of N-Heteroaromatic Trifluoromethoxy Compounds by Direct O-CF3Bond Formation.Liang, Apeng; Han, Shuaijun; Liu, Zhenwei; Wang, Liang; Li, Jingya; Zou, Dapeng*; Wu, Yangjie*; Wu, Yusheng*;Chem. Eur. J.,2016,22(15), 5102-5106.

11. Metal-Free Reduction of Aromatic Nitro Compounds to Aromatic Amines with B2pin2 in Isopropanol.Lu, Hongtao; Geng, Zhiyue; Li, Jingya; Zou, Dapeng*; Wu, Yusheng*; and Wu, Yangjie*.Org. Lett.,2016,18(11), 2774-2776.

12. One-pot double benzylation of 2-substituted pyridines using palladium-catalyzed decarboxylative coupling ofsp2 andsp3 carbons. Wang, Yaping; Li, Xinjian; Leng, Faqiang; Zhu, Helong; Li, Jingya; Zou, Dapeng*; Wu, Yangjie; Wu, Yusheng*.Adv. Syn. & catal.2014,356(16), 3307-3313.

13. Preparation oftert-Butyl Esters via Pd-catalyzedtert-Butoxycarbonylation of (Hetero)aryl Boronic Acid Derivatives. Li, Xinjian, Zou, Dapeng; Zhu, Helong; Wang, Yaping; Li, Jingya; Wu, Yangjie*, Wu, Yusheng*.Org. Lett.,2014,16(7), 1836-1839.

14. Facile synthesis of trifluoroethyl compounds by the Suzuki cross-coulping reactions ofCF3CH2OTs with arylboronic acids. Leng,Faqiang;Wang,Yaping;Li,Hui;Li,Jingya;Zou,Dapeng*; Wu,Yangjie;and Wu, Yusheng*;Chem. Commun,2013,49, 10697-10699.

15. Synthesis of 3,3-Disubstituted Oxoindoles by Visible-Light-Mediated Radical Reactions of Aryl Diazonium Salts with N-Arylacrylamides. Fu, Weijun*; Xu, Fengjuan; Fu, Yuqin; Zhu, Mei; Yu, Jiaqi; Xu, Chen; Zou, Dapeng*.J. Org. Chem.,2013,78(23), 12202-12206.

16. Arylation of 2-substituted pyridines via Pd-catalyzed decarboxylation cross-coupling reactions of 2-picolinic, Li, Xinjian; Zou, Dapeng; Leng, Faqiang; Sun, Chunxia; Li, Jingya; Wu, Yangjie*; Wu, Yusheng*.Chem. Commun,2013,49, 312-314.

17. The palladium-catalyzed cross-coupling reactions of trifluoroethyl iodide with aryl and heteroaryl boronic acid esters, Liang, Apeng; Li, Xinjian; Liu, Dongfeng; Li, Jingya; Zou, Dapeng*; Wu, Yangjie and Wu, Yusheng*.Chem. Commun,2012,48, 8273-8275.

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