李二庆，副教授，硕士生导师，郑州大学青年拔尖人才
邮箱：lierqing@zzu.edu.cn
电话：15038289596
课题组主页：https://www.x-mol.com/groups/duanzheng/people/3980
工作经历：
2020.06-至今 郑州大学 化学学院 副教授，郑州大学青年拔尖人才
2016.11-2020.06 郑州大学 化学学院 讲师（校聘副教授）
2015.08-2016.08 德国哥廷根大学 博士后 （adviser：Prof. Lutz F. Tietze）
学习经历：
2010.09-2015.06 南开大学 元素有机国家重点实验室 博士 导师：黄有 教授
2006.09-2010.06 河南师范大学 化学与化工学院 学士
研究方向：有机合成方法学，不对称催化，手性磷配体的设计合成，有机膦化学
主持项目
1. 国家自然科学基金青年基金项目：磷手性中心配体的设计、合成及在不对称催化领域的应用（基金号21702189），2018-2020 主持
2. 第11批中国博士后科学基金特别资助：新型1-磷杂降冰片二烯类手性配体参与的不对称反应研究（基金号2018T110737） 主持
3. 第61批中国博士后基金面上项目一等资助：手性膦催化剂的设计、合成及应用研究（基金号：2017M610458）主持
4. 河南省科技攻关项目：螺环羟吲哚化合物高立体选择性的合成及其活性研究（基金号：202102310004） 主持
5. 河南省博士后科研项目一等资助：磷手性中心配体的设计合成及应用研究（基金号001701006）主持
6. 郑州大学面上培育基金：1-磷杂降冰片烯类膦手性配体的从头设计及反应性能探究（基金号：(JC21253007）主持
发表论文
1. Yinggao Meng, Lihui Chen,* Er-Qing Li,* Recent Advances in Lewis Base-Catalysed Chemo-, Diastereo- and Enantiodivergent Reactions. Chem. Rec. 2022, DOI: 10.1002/tcr.202100276.
35. Manman Song, Jing Zhao, Er-Qing Li,* Recent advances in tertiary amine Lewis base-promoted cycloadditions of allenoates. Chin. Chem. Lett. 2022, https://doi.org/10.1016/j.cclet.2021.11.044.
3. Ke Li,† Zhipeng Zhang,† Jiahui Zhu, Yuxin Wang, Jing Zhao, Er-Qing Li* and Zheng Duan* Diastereodivergent Synthesis of Fully Disubstituted Spiro[indoline-3,2'-pyrrolidin]-2-ones via Tuneable Lewis base/Brønsted base-promoted (3+2) Cycloadditions. Org. Chem. Front. 2022, 9， 19-24. († These authors contributed equally to this work).
4. Siming Jia, Mengmeng Ma, Er-Qing Li,* Zheng Duan,* and Françis Mathey Design of 1 Phosphanorbornene Derivatives as Chiral Organocatalysts for Enantioselective (4 + 2) Annulation Reactions of γ Benzyl Allenoates. Org. Lett. 2021, 23, 3337-3342.
5. Wang Yue, Song Manman, Li Er-Qing*, and Duan Zheng* Auto-Tandem Palladium/Phosphine Cooperative Catalysis: Synthesis of Bicyclo[3.1.0]hexenes by Selective Activation of Morita–Baylis–Hillman Carbonates. Org. Chem. Front., 2021, 8, 3366-3371.
Ke Li, Zhenjie Gan, Er-Qing Li,* and Zheng Duan* Phosphine-Catalyzed (4 + 2) Cycloaddition of Conjugated Dienes with Enones and Its Asymmetric Variant. Org. Lett. 2021, 23, 3094-3099.
6. Lulu Wu, Bing Yu,* Er-Qing Li,* Recent Advances in Organocatalyst‐Mediated Benzannulation Reactions. Adv. Synth. Catal., 2020, 362, 4010-4126.
7. Lulu Wu, Kaihong Chen,* You Huang,* Er-Qing Li,* Phosphine‐Catalyzed δ‐Addition Reaction of γ‐Substituted Allenoates with Isatin Derivatives. Asian J. Org. Chem., 2020, 9, 1179-1182.
8. Er-Qing Li, You Huang,* Recent advances in phosphine catalysis involving γ-substituted allenoates. Chem. Commun., 2020, 56, 680-694
9. Ruiping Han, Yue Ding, Xueke Jin, Er-Qing Li,* Silver/palladium relay catalyzed 1,3-dipole annulation/allylation reactions to access fully substitutedallyl imidazolidines. Org. Biomol. Chem. 2020, 18, 646-649
10. Hao Cui, Ke Li, Yue Wang, Manman Song, Congcong Wang, Donghui Wei,* Er-Qing Li,* Zheng Duan* and Francois Mathey, Copper(I)/Ganphos Catalysis: Enantioselective Synthesis of Diversified Spirooxindoles Using Alkyl Substituted Imino Ester and Methyleneindolinones. Org. Biomol. Chem., 2020, 18, 3740-3746.
11. Yue Wang, Siming Jia, Er-Qing Li,* Zheng Duan,* Phosphine/Palladium Cooperative Catalysis: (4 + 3) Annulations of Morita–Baylis–Hillman Carbonates and Vinyl Benzoxazinanones. J. Org. Chem. 2019, 84, 15323-15330.
12. Zhenjie Gan, Yanchuan Gong, Yunpeng Chu, Er-Qing Li,* You Huang* and Zheng Duan* Phosphine-catalyzed regiodivergent annulations of γ-substituted allenoates with conjugated dienes. Chem. Commun., 2019, 55, 10120 - 10123.
13. Mengna Zhi, Zhenjie Gan, Rong Ma, Hao Cui, Er-Qing Li,* Zheng Duan,* François Mathey Ag/P-Stereogenic Phosphine-Catalyzed Enantioselective 1,3-Dipolar Cycloadditions: A Method to Optically Active Pyrrolidines. Org. Lett. 2019, 21, 3210-3213.
14. Zhenjie Gan, Mengna Zhi, Ruiping Han, Er-Qing Li,* Zheng Duan,* and François Mathey P-Stereogenic Phosphines Directed Copper(I)-Catalyzed Enantioselective 1,3-Dipolar Cycloadditions Org. Lett., 2019, 21, 2782–2785.
15. Yan-Chuan Gong, Yue Wang, Er-Qing Li,* Hao Cui, Zheng Duan* Enanti‐and Diastereoselective Synthesis of β‐Aryl‐β‐pyrazolyl α‐Amino Acid Esters via Copper‐Catalyzed Reaction of Azomethine Ylides with Benzylidenepyrazolones Adv. Synth. Catal. 2019, 361, 1389-1393.
16. 马蓉, 宋格格, 奚秋贞, 杨柳, 李二庆*, 段征* 有机磷催化γ-甲基联烯酸酯[3 + 2]环化反应 有机化学, 2019, 39, 2196-2202.
17. Qiu-Zhen Xi, Zhen-Jie Gan, Er-Qing Li,* Zheng Duan* Brønsted Acid Tuned, Lewis Base Promoted [4 + 2] Annulation Reactions of Allenoates with Electron-Deficient Olefins. Eur. J. Org. Chem. 2018, 2018, 4917-4925.
18. Erqing Li, Hongxing Jin, You Huang* Phosphine‐Catalyzed [3 + 2] Annulation of γ‐Substituted Allenoates: Novel Access to Functionalized Cyclopentenes and Bicyclic[3, 3, 0]octene Derivatives. ChemistrySelect 2018, 3, 12007-12010.
19. Erqing Li, Hongxing Jin, Penghao Jia, Xuelin Dong, You Huang* Bifunctional-Phosphine- Catalyzed Sequential Annulations of Allenoates and Ketimines: Construction of Functionalized Poly-heterocycle Rings. Angew. Chem. Int. Ed. 2016, 55, 11591 –11594.
20. Erqing Li, Meijia Chang, Ling Liang, You Huang* Divergent Phosphine Catalyzed [2 + 4] or [3 + 2] Cycloaddition Reactions of γ- Substituted Allenoates with Oxo-dienes. Eur. J. Org. Chem. 2015, 710-714.
21. Erqing Li, You Huang,* Phosphine-catalyzed Domino Reaction: A Novel Sequential [2+3] and [3+2] Annulation Reaction of γ-Substituent Allenoates to Construct Bicyclic[3, 3, 0]octene Derivatives. Chem. Commun., 2014, 50, 948-950.
22. Erqing Li, You Huang,* Phosphine-Catalyzed Domino Reaction: A Novel Method Access to Functionalized Bicyclic Skeletons. Chem. Eur. J., 2014, 20, 3520。
23. Erqing Li, Penghao Jia, Ling Liang, You Huang,* Phosphine-Catalyzed Sequential [2 +3] and [3 + 2] Annulation Domino Reaction of γ- Benzyl Substituted Allenoates with α,β-Unsaturated Ketimines To Construct Aza-bicyclo[3, 3, 0]octane Derivatives. ACS Catal. 2014, 4, 600-603.
24. Erqing Li, You Huang,* Ling Liang, Peizhong Xie, Phosphine-Catalyzed [4+2] Annulation of gamma-Substituent Allenoates: Facile Access to Functionalized Spirocyclic Skeletons. Org. Lett. 2013, 15, 3138-3141.
25. Erqing Li, Peizhong Xie, Lihua Yang, Ling Liang, You Huang* Tuning Catalysts to Tune the Products: Phosphine-Catalyzed Aza-Michael Addition Reaction of Hydrazones with Allenoates. Chem. Asian J. 2013, 8, 603-610.
授权专利：
段征，李二庆，支梦那，甘贞洁 手性1-磷杂降冰片二烯衍生物及其合成方法，专利号：ZL201811293427.X
