叶勇

作者: 时间:2021-04-03 点击数:

 

叶勇,教授,博士生导师

邮箱:yeyong@zzu.edu.cn

工作及研究经历:

2009--至今   郑州大学化学学院教授

2005--2009   郑州大学化学系副教授

2011, 11--2012, 12 英国曼彻斯特大学化学系访问学者

2003, 7--2005, 6 清华大学化学系博士后

2000, 9--2003, 6 南开大学元素所博士

1997, 9--2000, 7 南开大学元素所硕士

1991, 9--1995, 7 南开大学化学系学士

学术任职:教育部新世纪人才、河南省教育厅学术技术带头人

研究方向:1.化学生物学研究2.有机磷化学研究? 3.阻燃剂合成及应用研究

承担科研项目:

1. 2016-2019 “基于氧杂蒽的近红外活性硫比率荧光探针的合成和性能研究”编号21572209国家自然科学基金面上项目

2. 2012-2014 “新型荧光探针的合成及性能研究”编号NCET-11-0950教育部新世纪优秀人才项目

3. 2010-2012 “具有荧光的人工核酸酶的合成及其与核酸的相互作用研究”编号20972143国家自然科学基金资助项目

4.2007-2009 “环磷腈衍生物的合成及活性研究”编号20602032国家自然科学基金青年基金

近几年代表性论文:

1.J. Tang, X. Yang, F. Zhao, D. Zhang, S. Mo andY. Ye*, Visualizing peroxynitrite fluxes and protective effect of endogenous hydrogen sulfide during carbonyl stress in endothelial cell,Sens. Actuators, B,2021, 330, 129283.

2.X. Yang, J. Tang, D. Zhang, X. Han, J. Liu, J. Li, Y. Zhao andY. Ye*, An AIE probe for imaging mitochondrial SO2-induced stress and SO2levels during heat stroke,Chem. Commun.,2020,56, 13217-13220.

3.X. Yang, X. Han, Y. Zhang, J. Liu, J. Tang, D. Zhang, Y. Zhao andY. Ye*, Imaging Hg2+-Induced Oxidative Stress by NIR Molecular Probe with "dual-Key-and-Lock" Strategy,Anal. Chem.,2020, 92, 12002-12009.

4.S. Peng, Z. Li, Y. Zhang, W. Cao, J. Liu, W. Zhu andY. Ye*, A two-photon fluorescent probe for HNO rapid visualization in endoplasmic reticulum,Sens. Actuators, B,2020, 317,128211.

5.H. Niu, Y. Zhang, J. Tang, X. Zhu,Y. Ye*and Y. Zhao, A bifunctional fluorescent sensor for CCCP-induced cancer cell apoptosis imaging,Chem. Commun.,2020, 56, 12423-12426.

6.H. Niu, J. Tang, X. Zhu, Z. Li, Y. Zhang,Y. Ye*and Y. Zhao, A three-channel fluorescent probe to image mitochondrial stress,Chem. Commun., 2020,56, 7710-7713.

7.Z. Li, J. Li, D. Zhang, X. Zhu,Y. Ye*and Y. Zhao, A novel dual-channel fluorescent probe for nitroxyl detection and its application in HepG-2 cells,Sens. Actuators, B,2020, 312,127944 .

8.J. T. Hou, B. Wang, Y. Zhang, B. Cui, X. Cao, M. Zhang,Y. Ye*and S. Wang, Observation of peroxynitrite overproduction in cells during 5-fluorouracil treatment: Via a ratiometric fluorescent probe,Chem. Commun.,2020,56, 2759-2762.

9.X. Han, X. Yang, Y. Zhang, Z. Li, W. Cao, D. Zhang andY. Ye*,A novel activatable AIEgen fluorescent probe for peroxynitrite detection and its application in EC1 cells,Sens. Actuators, B,2020, 321, 128510.

10.X. Yang, Y. Wang, R. Liu, Y. Zhang, J. Tang, E. B. Yang, D. Zhang, Y. Zhao andY. Ye*, A novel ICT-based two photon and NIR fluorescent probe for labile Fe2+detection and cell imaging in living cells,Sens. Actuators, B,2019, 288, 217-224.

11.F. Qin, Y. Zhang, J. Zhu, Y. Li, W. Cao andY. Ye*, A mitochondrial-targeted fluorescent probe to sense pH and HOCl in living cells,Sens. Actuators, B,2019, 291, 207-215.

12.H. Niu, Y. Zhang, F. Zhao, S. Mo, W. Cao,Y. Ye*and Y. Zhao, Reductive stress imaging in the endoplasmic reticulum by using living cells and zebrafish,Chem. Commun.,2019, 55, 9629-9632.

13.H. Niu, K. Chen, J. Xu, X. Zhu, W. Cao, Z. Wang,Y. Ye*and Y. Zhao, Mitochondria-targeted fluorescent probes for oxidative stress imaging,Sens. Actuators, B,2019, 299,126938.

14.W. Liu, D. Zhang, B. Ni, J. Li, H. Weng andY. Ye*, Mitochondria-targeted and FRET based ratiometric fluorescent probe for SO2and its cell imaging,Sens. Actuators, B,2019, 284, 330-336.

15.X. Yang, W. Liu, J. Tang, P. Li, H. Weng,Y. Ye*, M. Xian, B. Tang and Y. Zhao, A multi-signal mitochondria-targeted fluorescent probe for real-time visualization of cysteine metabolism in living cells and animals,Chem. Commun.,2018, 54, 11387-11390.

16.J. Li, X. Yang, D. Zhang, Y. Liu, J. Tang, Y. Li, Y. Zhao andY. Ye*, A fluorescein-based “turn-on” fluorescence probe for hypochlorous acid detection and its application in cell imaging,Sens. Actuators, B,2018, 265, 84-90.

17.B. Zhang, X. Yang, R. Zhang, Y. Liu, X. Ren, M. Xian,Y. Ye*and Y. Zhao, Lysosomal-Targeted Two-Photon Fluorescent Probe to Sense Hypochlorous Acid in Live Cells,Anal. Chem.,2017, 89, 10384-10390. (高被引论文)

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