杨冉，博士，校聘教授，硕士生导师; yangran@zzu.edu.cn

研究方向：纳米材料光电传感；食品药品快速检测

学习及工作经历：

1995/09－1999/06 郑州大学 应用化学 学士

2000/09－2003/06 郑州大学 分析化学 硕士

2003/09－2006/06 中国药科大学 生药学 博士

2006/06－2014.04 郑州大学，化学学院，讲师

2014.05－至今 郑州大学，化学学院，副教授

2019.01－至今 郑州大学直聘教授

获奖及荣誉：

1.2020年度第十一届郑州大学我最喜爱老师

2.2020和2014年度郑州大学“三育人”先进个人

3.2013年度郑州大学优秀共产党员

4.2009年度郑州大学青年骨干教师

主持项目：

1. 国家自然科学基金-河南省联合基金，低电位高精准电化学探针的设计构建及应用（U1804136），2018.01-2021.12。

2. 国家自然科学基金-河南省联合基金，U1404214，氯酚类化合物表面分子印迹电化学传感器的构筑及性能研究，2015.01-2017.12。。

3. 河南省教育厅自然科学基金重点项目，12A150025，2万，磷酰化黄酮的抗氧化活性及体内代谢研究，2012.01-2014.12。

4. 郑州市科技局科技攻关，121PPTGG507-3，喹诺酮类抗生素化学发光酶免试剂盒的研制，2012.01-2014.12。

5. 河南省教育厅科技攻关14A150014,，基于石墨烯/量子点纳米复合物的环境酚类电化学传感试剂盒研制，2014.01-2015.12。

发表文章：

1. Zeng Huajin, Li Qiongyang, Ma Jiao,Yang Ran*, Qu Lingbo, A comparative study on the effects of resveratrol and oxyresveratrol against tyrosinase activity and their inhibitory mechanism, Spectrochim Acta Part A: Mol and Biomol Spect. 2021, 251, 119405.

2. Zeng Huajin, Sun Dongqin, Chu Shanhui, Zhang Jun Hu Guizhou,Yang Ran*. Inhibitory effects of four anthraquinones on tyrosinase activity: Insight from spectroscopic analysis and molecular docking, Inter J Biol macromol,2020, 160, 153-163.

3. Wang Ling, Li Xiao,Yang Ran*, Li Jianjun, Qu LIngbo. A Highly Sensitive and Selective Electrochemical Sensor for Pentachlorophenol Based on Reduced Graphite Oxide-Silver Nanocomposites,Food Anal Methods, 2020,13,2050-2058.

4. Sun, Yuanqiang#，Qin, Haoyue#，Geng, Xin，Yang, Ran*，Qu, Lingbo，Kani, Alexander Nti，Li, Zhaohui*. Rational Design of Far-Red to Near-Infrared Emitting Carbon Dots for Ultrafast Lysosomal Polarity Imaging, ACS Applied Materials & Interfaces,2020,12,31738-31744

5. Qin, Haoyue, Sun, Yuanqiang, Geng, Xin, Zhao, Keran, Meng, Hongmin,Yang, Ran*, Qu, Lingbo, Li, Zhaohui. A wash-free lysosome targeting carbon dots for ultrafast imaging and monitoring cell apoptosis status, Anal Chim Acta, 2020, 1106, 207-215

6. Yangyang Liu, Yiming Liang,Ran Yang*, Lingbo Qu. A highly sensitive and selective electrochemical sensor based on polydopamine functionalized graphene and molecularly imprinted polymer for the 2,4-dichlorophenol recognition and detection,Talanta, 2019,195, 691-698.

7. Wang Ling,Yang Ran*, Li Jianjun, Qu Lingbo*,A highly selective and sensitive electrochemical sensor for tryptophan based on the excellent surface adsorption and electrochemical properties of PSS functionalized graphene, Talanta, 2019, 196, 309-316.

8. Sun Lijun, Qu Lingbo,Yang Ran*, Zeng Huajin*. Cysteamine functionalized MoS2quantum dots inhibit amyloid aggregation,International Journal of Biological Macromolecules, 2019, 128,870-876

9. Hua-jin Zeng, Zhe Liu, Ya-ping Wang, Dan Yang,Ran Yang*, Ling-bo Qu, Studies on the anti-aging activity of a glycoprotein isolated from Fupenzi (Rubus chingii Hu,) and its regulation on klotho gene expression in mice kidney. International Journal of Biological Macromolecules, 2018, 119: 470-476

10. Huajin Zeng, Min Miao, Zhe Liu,Ran Yang*, Lingbo Qu. Effect of Nitrogen-doped graphene quantum dots on the fibrillation of hen egg-white lysozyme. International Journal of Biological Macromolecules, 2017, 95: 856-861.

11. Huajin Zeng, Min Miao,Ran Yang*, Lingbo Qu. Effect of silybin on the fibrillation of hen egg-white lysozyme. Journal of Molecular Recognition, 2017, 30: 2566

12. Yiming Liang, Lanlan Yu,Ran Yang∗, et al. High sensitive and selective graphene oxide/molecularly imprinted polymer electrochemical sensor for 2,4-dichlorophenol in water, Sensors and Actuators B,2017,240,1330–1335.

13. Yiming Liang, Ran Yang∗, Lingbo Qu, et al. Molecularly imprinted electrochemical sensor for daidzein recognition and detection based on poly(sodium 4-styrenesulfonate) functionalized graphene, Sensors and Actuators B 2017,251,542–550.

14. Rui Liu, Ran Yang*, Chaojie Qu, et al. Synthesis of glycine-functionalized graphene quantum dots as highly sensitive and selectivefluorescent sensor of ascorbic acid in human serum，Sensors and Actuators B,2017,241,644–651

15. Ling Wang,Ran Yang*, Jianjun Li, et al. A selective and sensitive tert-butylhydroquinone sensorbased on synergy of CTAB and AuNPs–PVP–graphene nanohybrids, Ionics, 2016, 22, 415–423.

16. Huajin Zeng, Yaping Wang,Ran Yang*, Jing You, Lingbo Qu. Inhibitory effects of daidzein and genistein on trypsin: insights from spectroscopic and molecular docking studies. International Journal of Biological Macromolecules, 2016, 89: 336-343

17. Huajin Zeng, Jing You, Huili Liang, Tingting Qi,Ran Yang*, Lingbo Qu, Investigation on the binding interaction between silybin and pepsin by spectral and molecular docking, International Journal of Biological Macromolecules, 2014, 67:105-111

18. Ran Yang, Dandan Miao, Yiming Liang, et al. Ultrasensitive electrochemical sensor based on CdTe quantum dots-decorated poly(diallyldimethylammonium chloride)-functionalized graphene nanocomposite modified glassy carbon electrode for the determination of puerarin in biological samples. Electrochim Acta, 2015,173,839-846.

19. Ling Wang,Ran Yang*, Jianjun Li, et al. High-sensitive electrochemical sensor of Sudan I based on template-directed self-assembly of graphene-ZnSe quantum dots hybrid structure. Sensor and Actuat B-Chem, 2015,215,181-187.

20. Ling Wang,Ran Yang*, Huan Wang, et al. High-selective and sensitive voltammetric sensor for butylated hydroxyanisole based on AuNPs-PVP-graphene nanocomposites.Talanta. 2015,138,169-175

21. Lianjun Li, Dandan Miao,Ran Yang*, et al. Synthesis of poly(sodium 4-styrenesulfonate) functionalized graphene/ cetyltrimethylammonium bromide (CTAB) nanocomposite and its application in electrochemical oxidation of 2,4-dichlorophen,Electrochim Acta, 2014,125,1–8.

22. Jianjun Li, Xiao Li,Ran Yang∗, et al. sensitive electrochemical chlorophenols sensor based on nanocomposite of ZnSe quantum dots and cetyltrimethylammonium bromide, Anal. Chim. Acta, 2013, 804, 76–83.

23. Lijuan Zi, Jianjun Li, Yexuan Mao,Ran Yang*, et al. High sensitive determination of theophyline based on gold nanoparticles/L-cystein/ Graphene/Nafion modified electrode.Electrochim. Acta, 2012,78,434- 439.

24. Hua-jin Zeng, Jing You, Hui-li Liang, Tingting Qi,Ran Yang*, et al. Investigation on the binding interaction between silybin and pepsinby spectral and molecular docking, Inter. J.Biological Macromol, 2014, 67,105–111.

25. Ran Yang, Lanlan Yu, Huajin Zeng, et al. The Interaction of flavonoid-lysozyme and the relationship between molecular structure of flavonoids and their binding activity to lysozyme, J.Fluorescence, 2012,22,1449-145.

出版专著：

1. 艾草及其艾草应用，2019，郑州大学出版社，主编

2. Applied Case Studies and Solutions in Molecular Docking-Based Drug Design，

81-126 2016，参编：3.0万字

3. 化学发光分析技术及其在药品食品分析中的应用，2012年化学工业出版社出版 参编3万字

4. 新型功能材料设计及应用，2014年郑州大学出版社，参编5万字。

获奖：

1.恩诺沙星化学发光酶免试剂盒的研制，2013年河南省教育厅优秀科技成果一等奖。

2.基于石墨烯纳米复合材料的光电传感快速检测，2018年河南省教育厅优秀科技成果一等奖。