朱艳艳
1979年12月，博士，副教授
邮箱：zhuyan@zzu.edu.cn
主要学习工作经历
1997.9—2001.6 郑州大学化学系本科生
2003.9—2006.6 郑州大学化学系硕士研究生
2006.9—2009.6 北京师范大学化学学院博士研究生
2009.10—2012.4 郑州大学化学与分子工程学院博士后
2009.7 — 2013.3 郑州大学化学与分子工程学院物理化学教研室讲师
2013.4 —至今 郑州大学化学与分子工程学院物理化学教研室副教授
2013.11 — 2014.6 / 2018.12—2019.12 美国肯塔基大学药学院访问学者
研究领域与方向
1、主客体分子识别
2、蛋白药物分子设计
3、新型有机反应机理探索
代表性教学成果与荣誉
1、讲授《结构化学》、《理论计算化学》、《量子化学》、《线性代数与群论》等课程，指导本科生、研究生科研工作。
2、荣获2020年河南省教学标兵，2020年河南省教学技能竞赛一等奖，郑州大学“三育人”先进个人，郑州大学青年骨干教师。
主持项目
1、金属核酸酶与DNA结合模式及切割活性的理论研究，国家自然科学基金委青年科学基金，21001095，2011-01至2013-12，19万元，已结题，主持
2、人工金属核酸酶与双链DNA作用模式的理论研究，第48批中国博士后科学基金面上项目，20100480858，2011-05至2013-12，3万元，已结题，主持
3、河南省教育厅重点科研项目，15A150082，氮杂环卡宾催化有机反应机理的理论探索，2015-01至2016-12，2万元，已结题，主持
代表性论文
1. Nan He,Yanyan Zhu*, Zhenhua Zhu, Yankai Yang, Wenjing Zhang, Donghui Wei, Lingbo Qu*, Mingsheng Tang, Hongsheng Chen*, A density functional theory study on mechanisms of [4+2] annulation of enal with alpha-methylene cycloalkanone catalyzed by N-heterocyclic carbene.Int. J. Quantum Chem.2020, 119, e26039.
2. Fengli Wei, Xuewei Huang, Zhaoxun Lian*,Yanyan Zhu*, Fengqi Guo*, Computational and experimental assessment on the nonlinear optical properties of platinum(II) arylacetylides with donor-acceptor structures,J. Organomet. Chem.2019, 904, 121003.
3. Xinqiang Cheng, Jiankai Shan, Xinshe Tian, Yun-Lai Ren*,Yanyan Zhu*, Benzylation of Arenes with Benzyl Halides under Promoter-Free and Additive-Free Conditions,Eur. J. Org. Chem.2019, 4404.
4. Hao Xu, Zhenhua Zhu, Yuen Guo, Chunmei Liu, Wenjing Zhang,Yanyan Zhu*, Yulong Wang, Mingsheng Tang, A DFT study on N-heterocyclic carbene catalyzed [4+2] annulation reaction with in situ generated heterocyclic ortho-quinodimethane: Mechanism, origin of enantioselectivity and role of catalyst,Tetrahedron2018, 74, 1009-1015.
5. Junyue Shen, Mengdi Wang, Yanfang Wang, Jingya Hu,Yanyan Zhu*, Yuxin Zhang*, Zhongjun Li, Hongchang Yao*, Iron and carbon codoped WO3with hierarchical walnut-like microstructure for highly sensitive and selective acetone sensor,Sens. Actuators B2018, 256, 27-37
6. Xiyan Dong,Xue Li,Bo Li,Yanyan Zhu*,Shuangquan Zang*,Mingsheng Tang, Water sandwiched by a pair of aromatic rings in a proton-conducting metal–organic framework,Dalton Trans.2016, 45, 18142-18146
7. Chunmei Liu,Yanyan Zhu*, Mingsheng Tang*, Theoretical studies on binding modes of copper-based nucleases with DNA,J. Mol. Graphics Model.2016, 64, 11-29
8. Chunmei Liu, Bin Zhang,Yanyan Zhu*, Mingsheng Tang*, Evaluations of AMBER force field parameters by MINA approachfor copper-based nucleases,Struct. Chem.2016, 27, 1449-1464
9. Xuening Zhang, Mingsheng Tang, Fangfang Li,Yanyan Zhu*, Chunmei Liu, Wenjing Zhang, Donghui Wei, Theoretical study on binding models of copper nucleases containing pyridyl groups to DNA,Theor. Chem. Acc.2015, 134, 94
10. Yunxia Li,Yanyan Zhu*, Wenjing Zhang, Donghui Wei*, Yingying Ran, Qilin Zhao, Mingsheng Tang, A DFT study on the reaction mechanism of dimerization of methyl methacrylate catalyzed by N-heterocyclic carbene,Phys. Chem. Chem. Phys.2014, 16,20001-20008
11. Zhenyu Li, Donghui Wei*, Yang Wang,Yanyan Zhu*, Mingsheng Tang, DFT study on the mechanisms and stereoselectivities of the [4 + 2] cycloadditions of enals and chalcones Catalyzed by N-Heterocyclic Carbene,J. Org. Chem.2014, 79, 3069-3078
12. Mengmeng Zhang, Donghui Wei*, Yang Wang, Suiji Li, Jiefei Liu,Yanyan Zhu*, Mingsheng Tang, DFT study on the reaction mechanisms and stereoselectivities of NHC-catalyzed [2 + 2] cycloaddition between arylalkylketenes and electron-deficient benzaldehydes,Org. Biomol. Chem.2014, 12, 6374-6383
13. Yanyan Zhu, Mingqiong Tong, Chunmei Liu, Chen Song, Donghui Wei*, Qilin Zhao, Mingsheng Tang, Molecular dynamics simulations on inclusion complexes for chiral enantiomers with heterocyclic cyclodecapeptide,Comput. Theor. Chem.2014, 1027, 46-52
14. Chunmei Liu,Yanyan Zhu*, Peipei Chen, Mingsheng Tang*, Theoretical simulations on interactions of mono- and dinuclear metallonucleases with DNA,J. Phys. Chem. B2013, 117, 1197-1209
15. Wenjing Zhang,Yanyan Zhu*, Donghui Wei, Yunxia Li, Mingsheng Tang*, Theoretical investigations toward the [4+2] cycloaddition of ketenes with N?benzoyldiazenes catalyzed by N?heterocyclic carbenes: mechanism and enantioselectivity,J. Org. Chem.2012, 77, 10729-10737
16. Wenjing Zhang,Yanyan Zhu*, Donghui Wei, Mingsheng Tang*,Mechanisms of the cascade synthesis of substituted 4-amino-1,2,4-triazol-3-one from huisgen zwitterion and aldehyde hydrazone: a DFT study,J. Comput. Chem.2012,33, 715-722
17. Hongge Zhao,Yanyan Zhu*, Mingqiong Tong, Juan He, Chunmei Liu, Mingsheng Tang*, Density functional theory studies on the inclusion complexes of cyclic decapeptide with 1-phenyl-1-propanol enantiomers,J. Mol. Model2012, 18, 851-858.
18. Donghui Wei,Yanyan Zhu*, Cong Zhang, Dongzhen Sun, Wenjing Zhang, Mingsheng Tang*, A DFT study on enantioselective synthesis of aza-β-lactams via NHC-catalyzed [2+2] cycloaddition of ketenes with diazene dicarboxylates,J. Mol. Catal A: Chemical2011, 334, 108-115
19. Cong Zhang,Yanyan Zhu*, Donghui Wei, Dongzhen Sun, Wenjing Zhang, Mingsheng Tang*, Theoretical study on the reaction mechanism between 6-Benzyl-6-azabicyclo [2.2.1]hept-2-ene and benzoyl isocyanate to urea and isourea,J. Phys. Chem. A2010,114,2913-2919.
20. Dongzhen Sun,Yanyan Zhu*, Donghui Wei, Cong Zhang, Wenjing Zhang, Mingsheng Tang*, Insight into the multicomponent reaction mechanisms of prop-2-en-1-amine and ethyl propiolate with alloxan derivative: a density functional theory study,Chem. Phys. Lett.2010, 495, 33-39.
21. Yanyan Zhu, Yan Wang*, Guangju Chen*, Differences in conformational dynamics of [Pt3(HPTAB)]6+–DNA adducts with various cross-linking modes,Nucleic Acids Res.2009, 37, 5930-5942
22. Yanyan Zhu, Yan Wang*, Guangju Chen*, Molecular dynamics simulations on binding models of Dervan-type polyamide + Cu(II) nuclease ligands to DNA,J. Phys. Chem. B2009, 113, 839-848
23. Yanyan Zhu,Yan Wang*,Guangju Chen*,Chang-Guo Zhan, A three-point method for evaluations of AMBER force field parameters: an application to copper-based artificial nucleases,Theor. Chem. Account2009, 122, 167-178.
24. Yanyan Zhu, Yanwei Su, Xichen Li, Yan Wang*, Guangju Chen*, Evaluation of AMBER force field parameters for copper(II) with pyridylmethyl- amine and benzimidazolylmethyl-amine ligands: a quantum chemical study,Chem. Phys. Lett.2008, 455, 354-360
