国家“万 人计划”领军人才,国家科技部创新人才推进计划领军人才。主要研究方向:癌症发病与外泌体摄入的机制问题,癌症的外泌体治疗,以及食品安全检测新技术。 近年主持基金项目: (1)国自然面上项目(81970173):原核纳米囊泡载miRNA靶向治疗多发性骨髓瘤的技术研究; (2)国自然面上项目(81472557):4.1N与EGFR作用抑制乳腺癌发生和去分化的机制研究 近年发表SCI论文: (1)Chen Z, Gao Y, Yao L, Liu Y, Huang L, Yan Z, Zhao W, Zhu P, Weng H*. LncFZD6 initiates Wnt/β-catenin and liver TIC self-renewal through BRG1-mediated FZD6transcriptional activation. Oncogene. 2018 Jun;37(23):3098-3112. (2)Yang X 1, Liu W , Tang J , Li P , Weng H* , Ye Y , Xian M , Tang B , Zhao Y . A multi-signal mitochondria-targeted fluorescent probe for real-time visualization of cysteinemetabolism in living cells and animals. Chem Commun (Camb). 2018 Oct 9;54(81):11387-11390. (3)Zhaowei Sun,Liuyang Tian,Min Guo,Xiaotong Xu,Qian Li,Haibo Weng* . Adouble-film screening card for rapid detection of organophosphate and carbamate pesticide residues by one step in vegetables and fruits. Food Control. 2017, 81, 23-29. (4) Pingping Li . Yang Zhou . Qian Li .Chong Zhang . Zhaowei Sun . Liuyang Tian .Haibo Weng Extending the linker region increases the activity of the Bacillus subtilis cellulase CelI15. Biotechnol Lett (2016) 38:1587–1593 近年授权国家发明专利: (1)一种快速检测试纸条以及采用该试纸条检测有机磷和氨基甲酸酯类农药残留的方法(CN201610980262.8) (2)重组乙酰胆碱酯酶在甲醇毕赤酵母中表达的中试发酵工艺(CN201510878108.5) (3)红林蚁AChE基因、红林蚁AChE及其制备方法( CN201510004412.7) (4)类人胸腺肽α1基因序列、类人胸腺肽α1及其制备方法(CN201510004144.9) |