基本信息:
姓名：蔡亚凡
出生年月：1990.01
籍贯：河南周口
学历：博士研究生
导师类别：硕士生导师
通信地址：河南省郑州市金水区文化路街道文化路97号
邮箱：caiyafan@zzu.edu.cn
教育/工作经历:
2025.12-至今 郑州大学 化工学院 生物+联合研究中心 直聘研究员（研究员）
2023.10-2025.11 郑州大学 化工学院 生物+联合研究中心 直聘研究员（副研究员）
2021.09-2023.09 郑州大学 化工学院 生物+联合研究中心 直聘研究员（助理研究员）
2019.09-2021.03 德国生物质工程中心（DBFZ） 生物转化部 博士后
2014.09-2019.06 中国农业大学 农学与生物技术学院 生物质工程专业 博士学位
招生方向/要求：本科专业为化工、环境、材料、新能源、微生物等相关专业。具有较强学习能力，有良好的英语听说读写能力，对科研具有强烈兴趣，积极主动，为人正直，勤奋踏实。
研究方向:
① 有机废弃物资源化（生物发酵蛋白饲料方向）
② 有机废弃物能源化（生物天然气工程方向）
③ 有机废弃物肥料化（生物有机肥料方向）
近年主要工作方向为有机废弃物饲料化、肥料化、能源化。主要研究成果如下：（1）：开发了以秸秆、酒糟等废弃物为原料的固态发酵蛋白饲料新设备，新工艺。 （2）：开发了厌氧消化氨抑制解除的生物强化剂，研究了“氨抑制稳定态”下生物强化作用机理。（3）：基于机器学习等手段开发了适用于厌氧消化的功能性生物炭，并揭示其辅助机理。（4）：开发了基于“生物电化学”的新型固定床厌氧生物反应器，并应用于有机废水处理。
社会兼职:
学术期刊Chemical engineering journal; Fuel; Renewable energy; Water research; Journal of Water Process Engineering; Bioresource technology; Waste management; Science of the Total Environment; Journal of Environmental Chemical Engineering; Bioresource Technology Reports; Journal of Environmental Management; Biomass Conversion and Biorefinery; Frontiers in Soil Science; Energy Nexus; Biotechnology Letters; Chemosphere; Environmental science and pollution research international等国际期刊审稿人。担任Biochar期刊编辑；担任Energies期刊“Novel Technologies for Organic Waste Processing and Utilization”方向客座编辑; 担任Frontiers in Bioengineering and Biotechnology客座编辑。担任Fermentation期刊“Solid-state fermentation”方向客座编辑
指导学生获奖：
① 2021级：瓮龙飞（硕士国家奖学金）
② 2022级：何云（硕士国家奖学金）；陈进孟（博士国家奖学金；金发科技奖学金；校十大优秀研究生）
③ 2023级：白雪珂（第十九届“挑战杯”揭榜挂帅专项赛全国总决赛特等奖），白雪珂（硕士国家奖学金）
④ 2024级：李帅（第十九届“挑战杯”揭榜挂帅主体赛全国总决赛一等奖）；陈进孟（入选2025年度中国科协青年科技人才培育工程博士生专项计划）
主持科研项目:
● 2023.01-2025.12；国家自然科学基金（青C），基于“氨抑制稳定态”的互营复合菌系生物强化及氨抑制解除机理解析，30万，主持；
● 2026.01-2027.01；绿色生物制造全国重点实验室开放课题，基于菌群理性设计的玉米秸秆固态发酵高效转化饲用蛋白关键技术研究，5万，主持；
● 2026.01-2027.12；河南省科技攻关，基于多菌系协同代谢的新疆棉秆定向转化饲用蛋白技术开发，10万，主持；
● 2023.10-2024.09；河南省科技攻关，“炭-菌”耦合定向调控氨抑制发酵性能技术开发，主持。
● 2023.08-2024.07；博士后基金面上项目，基于DIET途径强化的厌氧反应器开发及其在酱香型白酒废水处理中的应用， 8万，主持。
● 2023.01-2023.12；重点实验室开放课题，基于同步脱氮的白酒废水处理工艺开发，主持；
● 2021.09-2023.08；郑州大学启动基金，基于生物炭辅助的氨抑制稳定态下微生物的物质代谢机理，30万，主持；
● 2023.01-2024.12；横向课题，DIET途径辅助的酱香型白酒废水处理工艺开发，30万，主持
● 2023.01-2024.12；横向课题，菌酶协同发酵酒糟生产饲料蛋白技术开发，50万，主持。
● 2019.09-2021.03；中德学术交流中心博士后项目（CSC-DAAD），富氮底物厌氧消化高效调控策略及机理解 析，4.05万欧元，主持；
近5年代表性成果:
1. Yu, J., Usman, M., Liu, F., Schäfer, F., Shen, Y., Zheng, Z., Cai, Y*. 2025. CO2 agitation combined with magnetized biochar to alleviate“ammonia inhibited steady-state”: Exploring the mechanism by combining metagenomics with macroscopic indicators. Water Res. https://doi.org/10.1016/j.watres.2025.123250 (中科院一区).
2. Chen, J#., Cai, Y#., Wang, Z., Wang, S., Li, J., Song, C., Zhuang, W., Liu, D., Wang, S*., Song, A., Xu, J., Ying, H. 2024. Construction of a synthetic microbial community for enzymatic pretreatment of wheat straw for biogas production via anaerobic digestion. Environ. Sci. Technol. https://doi.org/10.1021/acs.est.4c02789 (中科院一区)
3. Wang, S., Wang, Z., Muhammad, U., Zheng, Z., Zhao, X., Meng, X., Hu, K., Shen, X., Wang, X., Cai, Y*., 2023. Two microbial consortia obtained through purposive acclimatization as biological additives to relieve ammonia inhibition in anaerobic digestion. Water Res. 230, 119583. https://doi.org/10.1016/j.watres.2023.119583 (中科院一区; 高被引论文)
4. Zheng, Z., Cai, Y*., Zhang, Y., Zhao, Y., Gao, Y., Cui, Z., Hu, Y., Wang, X*., 2021. The effects of C/N (10–25) on the relationship of substrates, metabolites, and microorganisms in “inhibited steady-state” of anaerobic digestion. Water Res. 188, 116466. https://doi.org/10.1016/j.watres.2023.119583 (中科院一区; 高被引论文)
5. Chen, J#., Cai, Y#., Guo, Z., Wang, Z., Ma, X., Liang, M., Xie, X., Zhuang, W., Liu, D., Zhu, C., Lv, Y., Zhao, A., Wang, S., Xu, J., Ying, H. 2025 Co-production of L-lactic acid and xylitol from corn stover by high-solid loading alkali-ammonia pretreatment. Chem. Eng. J. 524, 169517. https://doi.org/10.1016/j.cej.2025.169517. (中科院一区)
6. Chen, J., Liang, M., Wang, Z., Ma, X., Liu, J., Zhuang, W., Liu, D., Zhao, A., Lv, Y., Cai, Y*., Wang, S., Zhu, C., Xu, J., Ying, H. 2025. Mechanism analysis of NaOH-urea binary low-temperature high-solid pretreatment of corn stover and application in cellulosic ethanol production. Biomass and Bioenergy, 203, 108308. https://doi.org/10.1016/j.biombioe.2025.108308. (中科院二区)
7. Li, X., Wang, Z., Wang, X., Shen, C., He, Y., Li, S., Chen, J., Wang, S., Zhuang, W ., Meng, X., Cai, Y*., Xu, J., Ying, H. 2025. The Hydrochar Pre-Coupled Butyrate-Degrading Microbiome Assists the Bioenergy Production from Brewing Wastewater. Process. https://doi.org/10.3390/pr13082634. (中科院三区)
8. He, Y., Wang, Z., Shen, C., Wang, S., Liu, Y., Chen, S., Li, X., Zhao, X., Chen, J., Shi, J., Cai, Y*., Xu, J., Ying, H. 2025 Enhancing anaerobic digestion efficiency using biochars: Mechanisms and material perspectives. Renewable Energy 256, 124147. https://doi.org/10.1016/j.renene.2025.124147. (中科院一区)
9. Wang, F#., Cai, Y#., He, Y., Xu, Y., Ye, Y., Wang, S., Liu, D., Wang, Z., Xu, J., Ying, H. 2025. Improvement of feed nutritional value of sprayed corn bran through two-stage solid-state fermentation by non-protein nitrogen utilization microorganisms. J Sci Food. Agr. 105(15), 8625-8637. https://doi.org/10.1002/jsfa.70104. (中科院一区)
10. Ma, S., Yu, X., Harahap, B., Khan, M., He, H., Cai, Y*. Advances in anaerobic digestate management: functions and impacts of carbon and iron-based additives. Bioresour. Technol. 436, 133037. https://10.1016/j.biortech.2025.133037. (中科院一区)
11. He, Y., Wang, Z., Shen, C., Wang, S., Liu, Y., Li, X., Bai, X., Zhao, J., Zhao, X., Meng, X., Cai, Y*., Xu, J., Ying, H. 2025. Biochar-microorganisms hybrid enhanced anaerobic digestion: Innovative insight considering electron transfer potential and functional network of microorganisms. Bioresour. Technol. 435, 132928.https://10.1016/j.biortech.2025.132928. (中科院一区)
12. Bai, X., Wang, J., Wang, X., Li, S., Yang, Y., Sun, R., Wang, S., Zhao, X., Wang, Z., Cai, Y*., Xu, J., Ying, H. 2025. Pretreatment of Luzhou Distiller's Grains with Crude Enzyme from Trichoderma harzianum for Feed Protein Production. Fermentation. 11(5), 294, https://doi.org/10.3390/fermentation11050294. (中科院二区)
13. Ye, Y#., Cai, Y#., Wang, F., He, Y., Yang, Y., Guo, Z., Liu, M., Ren, H., Wang, S., Liu, D., Xu, J., Wang, Z. 2025. Industrial Microbial Technologies for Feed Protein Production from Non-Protein Nitrogen. 13(4), 742. https://doi.org/10.3390/microorganisms13040742. (中科院二区)
14. Chen, Y., Liu, F*., Ghofrani-lsfahani, P., Wang, P., Liu, Q., Cai, Y*., Gu, L. 2026. Metagenomics reveals the role of micron zero-valent iron in semi-continuous anaerobic digestion of food waste: The non-negligible impact of organic loading rate. Renewable Energy 256, 125202. https://doi.org/10.1016/j.renene.2026.125202 (中科院一区)
15. Li, X., Wang, S., Wang, X., He, Y., Li, S., Li, S., Chen, J., Wang, Z., Zhao, X., Cai, Y*., Xu, J., Ying, H. 2026. Magnetic biochar-assisted high-solid anaerobic digestion of chicken manure: Focusing on its mitigation mechanisms of ammonia inhibition. Fuel. 411, 137956. https://doi.org/10.1016/j.fuel.2025.137956 (中科院二区)
16. Guo, Z#., Cai, Y#., Liang, M., Ma, X., Wang, Z., Zhuang, W., Zhu, C., Lv, Y., Zhao, A., Wang, S., Xu, J., Ying, H. 2025. Recyclable alkaline pretreatment of corn stover under high-solid conditions: Improved hydrolysis, detoxification and fermentation with reduced water use. J. Environ. Chem. Eng. 13(6), 120012. https://doi.org/10.1016/j.jece.2025.120012. (中科院二区).
17. Cai, Y., Meng, X., Hu, K., Zhao, X., Muhammad, U., Esposito, G., Shen, X., Chen, S*., 2023. A novel strategy to reduce trace element supplementation in the semi-solid anaerobic digestion with gradient ammonia concentration: the role of biochar. Fuel. 338, 127332. https://doi.org/10.1016/j.fuel.2022.127332 (中科院一区)
18. He, Y., Wang, S., Shen, C., Wang, Z., Liu, Y., Meng, X., Li, X., Zhao, X., Chen, J., Xu, J., Yu, J*., Cai, Y*., Ying, H. 2024. Biochar accelerates methane production efficiency from Baijiu wastewater: Some viewpoints considering direct interspecies electron transfer (DIET). Chem. Eng. J. 497, 154527. https://doi.org/10.1016/j.cej.2024.154527 (中科院一区)
19. Cai, Y., Shen, X*., Meng, X., Zheng, Z., Hu, K., Zhao, X*., 2023. Syntrophic consortium with the aid of coconut shell-derived biochar enhances methane recovery from ammonia inhibited anaerobic digestion. Sci Total Environ. 872, 162182. https://doi.org/10.1016/j.scitotenv.2023.162182 (中科院一区)
20. Wang, S., Wang, Z., Wang, N., Wang, S., Zeng, S., Xu, Z., Liu, D., Zhao, X., Liu, F., Xu, J., Cai, Y*., Ying, H. 2025. Efficient conversion of corn straw to feed protein through solid-state fermentation using a thermophilic microbial consortium.Waste Manage. 194, 298-308. https://doi.org/10.1016/j.wasman.2025.01.023 (中科院二区)
21. Gao, Y., Hussain, I., Liu, Y., Huang, X., Chai, Y., Zheng, Z., Cai, Y*., Wang, X*. 2024. An innovative technology for producing agricultural Jiaosu from fruit waste without additional sugar and water: Fermentation characteristics, microbial community, and its impact on the growth of pakchoi. Chem. Eng. J. 499, 156538. https://10.1016/j.cej.2024.156538 (中科院一区)
22. Cai, Y., Gallegos, D., Zheng, Z., Stinner, W., Pröter, J., Schäfer, F*., 2021. Exploring the combined effect of total ammonia nitrogen, pH and temperature on anaerobic digestion of chicken manure using response surface methodology and two kinetic models. Bioresour. Technol. 337, 125328. https://doi.org/10.1016/j.biortech.2021.125328 (中科院一区)
23. Cai, Y*., Zhu, M., Meng, X., Zhou, J., Zhang, H., Sheng, X., 2022. The role of biochar on alleviating ammonia toxicity in anaerobic digestion of nitrogen-rich wastes: A review. Bioresour. Technol. 351, 126924. https://doi.org/10.1016/j.biortech.2022.126924 (中科院一区)
24. Gao, Y., Song, C., Usman, M., Zheng, Z., Meng, X., Shen, X., Cai, Y*., Wang, X. 2024. Pretreatment of wheat straw using ammonia rich-liquid fraction of digestate: Contribution of biological and non-biological components in methane yield. Ind. Crop. Prod. 220, 119262. https://doi.org/10.1016/j.indcrop.2024.119262 (中科院一区)
25. Usman, M., Shi, Z., Cai, Y., Zhang, S., Luo, G*. 2023. Microbial insights towards understanding the role of hydrochar in enhancing phenol degradation in anaerobic digestion. Environ. Pollut. 330, 121779. https://doi.org/10.1016/j.envpol.2023.121779 (中科院二区)
26. Cai, Y., Zheng, Z., Zhang, H., Wei, L., Wang, X., 2021. The characteristics of multi-substrates (low and high C/N) anaerobic digestion: Focus on energy recovery and the succession of methanogenic pathway. Bioresour. Technol. 343, 125976. https://doi.org/10.1016/j.biortech.2021.125976 (中科院一区)
27. Cai, Y., Janke, L., Meng, X., Zheng, Z., Zhao, X., Proter, J., Schafer, F., 2022. The absolute concentration and bioavailability of trace elements: Two vital parameters affecting anaerobic digestion performance of chicken manure leachate. Bioresour. Technol. 350, 126909. https://doi.org/10.1016/j.biortech.2022.126909 (中科院一区)
28. Cai, Y., Zheng, Z., Wang, X., 2021. Obstacles faced by methanogenic archaea originating from substrate-driven toxicants in anaerobic digestion. J. Hazard. Mater. 403, 123938. https://10.1016/j.jhazmat.2020.123938 (中科院一区)
29. Cai, Y., Janke, L., Zheng, Z., Wang, X., Proter, J., Schafer, F., 2021. Enhancing anaerobic digestion of chicken manure leachate: Effects of trace elements supplementation on methane production. Bioresour. Technol. Rep. 14, 100662. https://10.1016/j.biteb.2021.100662
30. Hua, B., Cai, Y., Cui, Z., Wang, X., 2022. Bioaugmentation with methanogens cultured in a micro-aerobic microbial community for overloaded anaerobic digestion recovery. Anaerobe. 706， 102603. https://doi.org/10.1016/j.anaerobe.2022.102603 (中科院三区)
31. Chen, J#., Cai, Y#., Wang, Z., Xu, Z., Zhuang, W., Liu, D., Lv, Y., Xu, J., Wang, S*., 2024. Ying, H. Solid-state fermentation of corn straw using synthetic microbiome to produce fermented feed: the feed quality and conversion mechanism. Sci Total Environ. 920, 171034. https://doi.org/10.1016/j.scitotenv.2024.171034 (中科院一区)
32. Liu, J#., Wang, S#., Wang, Z., Shen, C., Liu, D., Shen, X., Weng, L., He, Y., Wang, S., Wang, J., Zhuang, W., Cai, Y*., Xu, J., Ying, H. 2023. Pretreatment of Luzhou distiller's grains for feed protein production using crude enzymes produced by a synthetic microbial consortium. Bioresour. Technol. 390, 129852. https://doi.org/10.1016/j.biortech.2023.129852 (中科院一区)
33. Chen, J#., Cai, Y#., Wang, Z., Xu, Z., Li, J., Ma, X., Zhuang, W., Liu, D., Wang, S*., Song, A., Xu, J., Ying, H. 2023. Construction of a synthetic microbial community based on multiomics linkage technology and analysis of the mechanism of lignocellulose degradation. Bioresour. Technol. 389, 129799. https://doi.org/10.1016/j.biortech.2023.129799 (中科院一区)
34. Wang, Z., Wang, S., Zhuang, W., Liu, J., Meng, X., Zhao, X., Zheng, Z., Chen, S., Ying, H., Cai, Y*. 2023. Trace elements' deficiency in energy production through methanogenesis process: Focus on the characteristics of organic solid wastes. Sci Total Environ. 878, 163116. https://doi.org/10.1016/j.scitotenv.2023.163116 (中科院一区)
35. Gao, Y., Zheng, Z., Cheng, X., Zhang, Y., Liu, X., Hu, Y., Cai, Y*., Wang, X*. 2023. An innovative way to treat cash crop wastes: The fermentation characteristics and functional microbial community using different substrates to produce Agricultural Jiaosu. Environ. Res. 227, 115727. https://doi.org/10.1016/j.envres.2023.115727 (中科院二区)
36. Cai, Y., Zheng, Z., Schafer, F., Stinner, W., Yuan, X., Wang, H., Cui, Z., Wang, X., 2021. A review about pretreatment of lignocellulosic biomass in anaerobic digestion: achievement and challenge in Germany and China. J. Clean. Prod. 299, 126885. https://10.1016/j.jclepro.2021.126885 (中科院一区; 高被引论文)
1. 蔡亚凡、沈才洪、何云、刘淼、王石垒、杨平、王志、李晓勇、应汉杰。“磁-碱”联合改性生物炭的制备方法及其在酱香型白酒废水处理中的应用。发明专利申请号：申请日期：2023年12月04日。
2. 蔡亚凡、沈才洪、何云、许涛、王志、李姝、王石垒、刘光钱、于佳动、李晓勇、庄伟、应汉杰。提升白酒废水厌氧消化能力的生物强化剂及其合成方法和应用。发明专利申请号：CN202410678752.7。
3. 蔡亚凡、沈才洪、李晓勇、王松涛、王志、敖宗华、王石垒、宋川、何云、庄伟、应汉杰。适用于辅助酱香型白酒废水厌氧消化的“炭-菌”耦合物及其合成方法和应用。发明专利申请号：CN202410511523.6。
4. 白雪珂、王家鑫、李晓勇、何云、何祎、王思敏、王楠、王飞。第十九届挑战杯全国总决赛特等奖。指导教师：蔡亚凡、王石垒、王志。项目顾问：应汉杰。
5. 李帅，孙若雅，杨燕妮，李仕如，白雪珂，孔松林，李晓勇，王思敏。第十九届挑战杯全国总决赛一等奖。指导教师：蔡亚凡、王石垒、王志。项目顾问：应汉杰。
信息更新于2026.03.02
