序号 |
年度 |
论文名称 |
期刊,年,卷,期 |
作者 |
贡献 |
1 |
2020 |
A natural drug entry channel in the ferritin nanocage |
Nano Today, 2020; 35: 100948. |
江冰 |
第一 |
2 |
2020 |
Ferritins as natural and artificial nanozymes for theranostics |
Theranostics, 2020,10(2): 687-706. |
江冰 |
第一 |
3 |
2020 |
Extracellular vesicles: the next generation of biomarkers for liquid biopsy-based prostate cancer diagnosis. |
Theranostics, 2020,10(5): 2309-2326. |
李勇 |
通讯 |
4 |
2020 |
Discovery of tertiary amidederivatives incorporating benzothiazole moiety as anti-gastric cancer agents invitro via inhibiting tubulin polymerization and activating the Hipposignaling pathway |
European Journal of Medicinal Chemistry, 2020, 203, 112618. |
张赛扬 |
通讯 |
5 |
2020 |
Discoveryof novel tertiary amide derivatives as NEDDylation pathway activators toinhibit the tumor progression in vitro and in vivo |
European Journal of Medicinal Chemistry, 2020, 192, 112153 |
张赛扬 |
通讯 |
6 |
2020 |
Impact of obese levels on the hepatic expression of nuclear receptors and drug-metabolizing enzymes in adult and offspring mice |
Acta Pharmaceutica Sinica B, 2020, 10(1): 171-185. |
王沛 |
第一 |
7 |
2020 |
Discovery of new thieno[3,2-d]pyrimidine derivatives targeting EGFRL858R/T790M NSCLCs by the constrained strategy. |
European Journal of Medicinal Chemistry. 2020.199 (2020) |
杨琳琳 |
第一 |
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8 |
2021 |
LncRNA GIRGL drives CAPRIN1-mediated phase separation to suppress glutaminase-1 translation under glutamine deprivation. |
Sci Adv. 2021,7(13) 2375-2548. |
张莉蓉 |
通讯 |
9 |
2021 |
The Emerging Roles of RNA m(6)A Methylation and Demethylation as Critical Regulators of Tumorigenesis, Drug Sensitivity, and Resistance. |
Cancer Res. 2021,81(13):3431-40. |
张莉蓉 |
通讯 |
10 |
2021 |
Design, synthesis and evaluation of novel bis-substituted aromatic amide dithiocarbamate derivatives as colchicine site tubulin polymerization inhibitors with potent anticancer activities |
European Journal of Medicinal Chemistry, 2022, 229, 114069 |
张赛扬 |
通讯 |
11 |
2021 |
Discovery of 1,2,4-triazine dithiocarbamate derivatives as NEDDylation agonists to inhibit gastric cancers |
Eur J Med Chem. 2021 Aug 26;225:113801. |
张赛扬 |
通讯 |
12 |
2021 |
Discovery of novel indole derivatives that inhibit NEDDylation and MAPK pathways against gastric cancer MGC803 cells |
Bioorganic chemistry. 2021, 107, 104634. |
张赛扬 |
通讯 |
13 |
2021 |
Ferritin nanocages for early theranostics of tumors via inflammation-enhanced active targeting |
Science China Life Sciences, 2021, 1-13. |
江冰 |
第一 |
14 |
2021 |
Potential regulatory role of epigenetic RNA methylation in cardiovascular diseases. |
Biomed Pharmacother. 2021 May;137:111376. |
韩圣娜 |
通讯 |
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15 |
2022 |
The long noncoding RNA glycoLINC assembles a lower glycolytic metabolon to promote glycolysis |
Mol Cell. 2022, 82(3):542-554. |
张莉蓉 |
通讯 |
16 |
2022 |
The caspase-1 inhibitor VX765 upregulates connexin 43 expression and improves cell-cell communication after myocardial infarction via suppressing the IL-1β/p38 MAPK pathway. |
Acta Pharmacol Sin. 2022. |
张莉蓉、韩圣娜 |
通讯 |
17 |
2022 |
Discovery of novel coumarin-indole derivatives as tubulin polymerization inhibitors with potent anti-gastric cancer activities |
European Journal of Medicinal Chemistry, 2022, 238, 114467 |
张赛扬 |
通讯 |
18 |
2022 |
Design, synthesis and evaluation of novel bis-substituted aromatic amide dithiocarbamate derivatives as colchicine site tubulin polymerization inhibitors with potent anticancer activities. |
Eur J Med Chem. 2022 Feb 5;229:114069. |
张赛扬 |
通讯 |
19 |
2022 |
Discovery of N-benzylarylamide derivatives as novel tubulin polymerization inhibitors capable of activating the Hippo pathway. |
Eur J Med Chem. 2022 Oct 5;240:114583. |
张赛扬 |
通讯 |
20 |
2022 |
The proteomic characterization of the peritumor microenvironment in human hepatocellular carcinoma. |
Oncogene. 2022;41(17):2480-2491. |
乔海灵 |
通讯 |
21 |
2022 |
Bis-chalcone polyphenols with potential preventive and therapeutic effects on PD: Design, synthesis and in vitro disaggregation activity against alpha-synuclein oligomers and fibrils. |
Eur J Med Chem, 2022. |
徐霁 |
通讯 |
22 |
2022 |
Mitochondria-targeted nanozymes eliminate oxidative damage in retinal neovascularization disease. |
J Control Release. 2022 Oct;350:271-283. |
江冰 |
通讯 |
23 |
2022 |
Antigen-bearing outer membrane vesicles as tumour vaccines produced in situ by ingested genetically engineered bacteria. |
Nature Biomedical Engineering, 2022 |
岳娅乐 |
第一 |
24 |
2023 |
The dual FAK-HDAC inhibitor MY-1259 displays potent activities in gastric cancers in vitro and in vivo |
Bioorganic Chemistry, 2023, 131, 106328 |
张赛扬 |
通讯 |
25 |
2023 |
Tubulin degradation: Principles, agents, and applications |
Bioorganic Chemistry, 2023, 139, 106684 |
张赛扬 |
通讯 |
26 |
2023 |
Design, synthesis and biological evaluation of novel 2,4-diaminopyrimidine cinnamyl derivatives as inhibitors of FAK with potent anti-gastric cancer activities |
Bioorganic Chemistry, 2023, 141, 106895 |
张赛扬 |
通讯 |
27 |
2023 |
Discovery of novel tranylcypromine-based derivatives as LSD1 inhibitors for gastric cancer treatment |
European Journal of Medicinal Chemistry, 2023, 251, 106328 |
张赛扬 |
通讯 |
28 |
2023 |
Discovery of novel N-benzylarylamide-dithiocarbamate based derivatives as dual inhibitors of tubulin polymerization and LSD1 that inhibit gastric cancers |
European Journal of Medicinal Chemistry, 2023, 252, 115281 |
张赛扬 |
通讯 |
29 |
2023 |
A review of progress in o-aminobenzamide-based HDAC inhibitors with dual targeting capabilities for cancer therapy dual targeting capabilities for cancer therapy |
European Journal of Medicinal Chemistry, 2023, 259, 115673 |
张赛扬 |
通讯 |
30 |
2023 |
Design, synthesis and biological evaluation of N-benzylaryl cinnamide derivatives as tubulin polymerization inhibitors capable of promoting YAP YAP degradation with potent anti-gastric cancer activities |
European Journal of Medicinal Chemistry, 2023, 262, 115883 |
张赛扬 |
通讯 |
31 |
2023 |
Discovery of a novel Coumarin-Dihydroquinoxalone derivative MY-673 as a tubulin polymerization inhibitor capable of inhibiting the ERK pathway with potent anti-gastric cancer activities |
Bioorganic Chemistry, 2023, 137, 106580 |
张赛扬 |
通讯 |
32 |
2023 |
Immunogenic cell death effects induced by doxorubicin improved chemo-immunotherapy via restoration of granzyme B activity. |
Nano Research |
祁迎秋 |
通讯 |
33 |
2023 |
Identification of LRG1 targeting peptide and its application in targeted in targeted imaging for breast cancer |
Nano Research |
祁迎秋 |
通讯 |
34 |
2023 |
Modularly Designed Peptide-Based Nanomedicine Inhibits Angiogenesis to Enhance Chemotherapy for Post-Surgical Recurrence of Esophageal Squamous Cell Carcinomas |
Nano Research 2023, Jan 12; 16, pages7347–7354 |
岳娅乐 |
通讯 |
35 |
2023 |
Discovery of Novel 1,3-Diphenylpyrazine Derivatives as Potent S-Phase Kinase-Associated Protein 2 (Skp2) Inhibitors for the Treatment of Cancer |
J Med Chem 2023;66(11):7221-7242. |
张莉蓉 |
通讯 |
36 |
2023 |
WD repeat protein 54-mediator of ErbB2-driven cell motility 1 axis promotes bladder cancer tumorigenesis and metastasis and impairs chemosensitivity |
Cancer letters 2023; 556 |
张莉蓉 |
通讯 |
37 |
2023 |
Hybrids of polyphenolic/quinone acids, the potential preventive and therapeutic drugs for PD: Disaggregate α-Syn fibrils, inhibit inclusions, and repair damaged neurons in mice |
European Journal of Medicinal Chemistry 2023 Mar 5:249:115122. |
徐霁 |
通讯 |
38 |
2023 |
Structural insights into anion selectivity and activation mechanism of LRRC8 volume-regulated anion channels.
|
Cell Reports 2023;42(8):112926. |
杨琳琳 |
通讯 |
39 |
2023 |
An Association Study of HLA with Levofloxacin-Induced Severe Cutaneous Adverse Drug Reactions in Han Chinese |
iScience 2023 Jul 13;26(8):107391. |
杨琳琳 |
第一 |
40 |
2023 |
Engineering Multifunctional Thylakoid as an Oxygen Self-Supplying Photosensitizer for Esophageal Squamous Cell Carcinoma-Targeted Photodynamic Therapy |
CCSChemistry,2023, 5, 2519–2533 |
江冰 |
通讯 |
41 |
2023 |
Tackling Esophageal Squamous Cell Carcinoma with ITFn-Pt(IV): A Novel Fusion of PD-L1 Blockade,Chemotherapy, and T-cell Activation |
Advanced Healthcare Materials 2023, 2303623 |
江冰 |
通讯 |
42 |
2023 |
Identification of Cytochrome P450 2E1 as a Novel Target in Glioma and Development of Its Inhibitor as an Anti-Tumor Agent |
Advanced Science.2023;10(23):e2301096. |
乔海灵 |
通讯 |
43 |
2023 |
A Novel Cytochrome P450 2E1 Inhibitor Q11 Is Effective on Lung Cancer via Regulation of the Inflammatory Microenvironment |
Advanced Science.2023;10(35):e2303975. |
乔海灵 |
通讯 |
44 |
2023 |
Responsive Nanoparticles with Multilevel Triggered Drug Penetration for Tumor Photochemotherapy. |
ACS Applied Materials & Interfaces |
岳娅乐 |
第一 |