李业奇 讲师


李业奇,讲师,博士毕业于南京师范大学,毕业后在美国佐治亚大学从事博士后研究。2026年5月起在郑州大学基础医学院微生物与免疫学系任职。当前主要研究方向:1. 感染疾病免疫治疗与预防;2. 真菌感染免疫;3. 真菌抗原鉴定与疫苗研发;4. 真菌致病性研究。相关研究成果以第一作者(含共同第一作者)在国际专业学术期刊发表论文十余篇,包括PNASPLoS PathogensmBioNPJ Vaccines等。

代表性文章:

1. Li Y, Pham T, Hipsher K, Lee C, Jiao J, Penninger MJ, Kronstad WJ, Fan Y, Zhao Y, Ambati S, Meagher BR, Xie X, and Lin X. Identification of a protective antigen reveals the trade-off between iron acquisition and antigen exposure in a global fungal pathogen. Proc Natl Acad Sci U S A. 2025 Feb 13; 122 (7) e2420898122.

2. Li Y, Zhang Y, Zhang C, Wang H, Wei X, Chen P, Lu L. Mitochondrial dysfunctions trigger the calcium signaling-dependent fungal multidrug resistance. Proc Natl Acad Sci U S A. 2020 Jan 21;117(3):1711-1721. (Commentary: Bowyer et al., Linking calcium signaling and mitochondrial function in fungal drug resistance. Proc Natl Acad Sci U S A. 2020 Jan; 117 (3) 1254-1256)

3. Li Y, Meagher BR, and Lin X. Tailor mRNA nanoparticles for antifungal vaccines. PLoS Pathog. 2025 Apr 28; 21 (4), e1013091.

4. Li Y, Ambati S, Meagher BR, and Lin X. Developing mRNA lipid nanoparticle vaccine for cryptococcosis. NPJ Vaccines. 2025 Feb 04; 10(1):24.

5. Li Y, Chadwick B, Pham T, Xie X, Lin X. Aspartyl peptidase May1 induces host inflammatory response by altering cell wall composition in the fungal pathogen Cryptococcus neoformans. mBio. 2024 Jun 12;15(6):e0092024.

6. Pham T#, Li Y#, Watford W, Lin X. Vaccination with a ZNF2oe Strain of Cryptococcus Provides Long-Lasting Protection against Cryptococcosis and Is Effective in Immunocompromised Hosts. Infect Immun. 2023 Jul 18;91(7):e0019823. (# co-first author)

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