职称：助理研究员

         邮箱：wangjunyong@zzu.edu.cn

         地址：医学科学院博后楼1楼118室

个人简介

2020年6月毕业于武汉大学医学研究院，获基础医学博士学位。2020年11月至2021年10月，在武汉大学人民医院任助理研究员。2021年12月入职郑州大学医学科学院，任助理研究员。

主要研究方向

主要从事脂肪肝和食管癌等消化系统疾病的发病机制研究

荣誉及获奖情况

2022年 国家自然科学基金-青年科学基金资助

代表性成果

1)Wang JY^#, Guo Y^#, He Y, Qin Y, Li X, Yang L, Liu K^* and Xiao L^*. Hepatic regulator of G protein signaling 14 ameliorates NAFLD through activating cAMP-AMPK signaling by targeting Giα1/3. Molecular Metabolism.2024;80:101882.

2)Wang JY^#, Wang Z^#, Wang Q, Li X and Guo Y^*. Ubiquitous protein lactylation in health and diseases. Cell Mol Biol Lett. 2024;29:23.

3)Shi Y^#, Yuan Q^#, Chen Y, Li X, Zhou Y, Zhou H, Peng F, Jiang Y, Qiao Y, Zhao J, Zhang C, Wang JY^*, Liu KD^* and Dong ZG^*. Corynoline inhibits esophageal squamous cell carcinoma growth via targeting Pim-3. Phytomedicine. 2024;123:155235.

4)Wang JY^#, Ma J^#, Nie H^#, Zhang XJ, Zhang P, She ZG, Li H^*, Ji YX^* and Cai J^*. Hepatic Regulator of G Protein Signaling 5 Ameliorates Nonalcoholic Fatty Liver Disease by Suppressing Transforming Growth Factor Beta-Activated Kinase 1-c-Jun-N-Terminal Kinase/p38 Signaling. Hepatology. 2021;73:104-125.

5)Zhang XJ^*#, She ZG^#, Wang JY^#, Sun D^#, Shen LJ, Xiang H, Cheng X, Ji YX, Huang YP, Li PL, Yang X, Cheng Y, Ma JP, Wang HP, Hu Y, Hu F, Tian S, Tian H, Zhang P, Zhao GN, Wang L, Hu ML, Yang Q, Zhu LH, Cai J, Yang J, Zhang X, Ma X, Xu Q, Touyz RM, Liu PP, Loomba R, Wang Y^* and Li H^*. Multiple omics study identifies an interspecies conserved driver for nonalcoholic steatohepatitis. Science Translational Medicine. 2021;13:eabg8117.

6)Wang JY^#, Zeng Y^#, Xu S, Yang J, Wang W, Zhong B, Ge J, Yin L, Bu Z, Shu HB, Chen H, Lei CQ^* and Zhu Q^*. A Naturally Occurring Deletion in the Effector Domain of H5N1 Swine Influenza Virus Nonstructural Protein 1 Regulates Viral Fitness and Host Innate Immunity. J Virol. 2018;92.

7)Wang JY^#, Lei CQ^*, Ji Y, Zhou H, Ren Y, Peng Q, Zeng Y, Jia Y, Ge J, Zhong B, Li Y, Wei J, Shu HB and Zhu Q^*. Duck Tembusu Virus Nonstructural Protein 1 Antagonizes IFN-β Signaling Pathways by Targeting VISA. J Immunol. 2016;197:4704-4713.