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李永娟

作者: 时间:2024-04-04 点击数:

       职称:副教授

       邮箱yjli@zzu.edu.cn

       地址:郑州大学第一附属医院9号楼322

 

 

 






个人简介

2019年毕业于苏州大学,理学博士学位。2020年入职郑州大学,青年拔尖。硕士生导师,主要从事纳米药物的开发利用,肿瘤微环境免疫调控等方面的研究。近年来主持国自然基金1项,河南省自然科学基金面上1项,在Adv. Mater., Adv. Funct. Mater., ACS Centr. Sci., ACS Nano, Adv. Healthcare Mater.等国际知名杂志发表文章 20余篇。


 

主要研究方向

有机高分子聚合物,纳米载体,免疫治疗,免疫微环境调控。

 


代表性成果

1.Li Yongjuan; Cao Yongjian; Ma Kunru; Ma Rong; Zhang Mengzhe; Guo Yichen; Song Haiwei; Sun Nannan*; Zhang Zhenzhong*; Yang Weijing*; A Triple‐Responsive Polymeric Prodrug Nanoplatform with Extracellular Ros Consumption and Intracellular H2O2 Self‐generation for Imaging‐Guided Tumor Chemo‐Ferroptosis‐Immunotherapy, Advanced Healthcare Materials, 2024

2. Li Yongjuan*; Zhang Yu; Dong Ya; Akakuru Ozioma Udochukwu; Yao Xiaohan; Yi Jinmeng; Li Xinyan; Wang Linlin; Lou Xiaohan; Zhu Baoyu; Fan Kelong*; Qin Zhihai*; Ablation of gap junction protein improves the efficiency of nanozyme-mediated catalytic/starvation/mild-temperature photothermal therapy, Advanced Materials, 2023,高引用论文

3. Yang Weijing; Yi Jinmeng; Zhu Rongrong; Guo Yichen; Zhang Kaixin; Cao Yongjian; Li Xinyan; Zhang Jinjie; Zhang Zhenzhong; Li Yongjuan*; Chen Xiaoyuan*; Transformable prodrug nanoplatform via tumor microenvironment modulation and immune checkpoint blockade potentiates immunogenic cell death mediated cancer immunotherapy, Theranostics, 封面论文

4. Li Yongjuan*; Lei Ningjing; Yao Xiaohan; Zhang Yu; Dong Ya; Yin Jinmeng; Li Xinyan; Deng Wenjing; Nie Guangjun; Qin Zhihai ; Hijacking endogenous iron and GSH via a polyvalent ferroptosis agonist to enhance tumor immunotherapy, Advanced Functional Materials, 2023

5. Yongjuan Li, Yichen Guo, Kaixin Zhang, Rongrong Zhu, Xiaoyuan Chen,* Zhenzhong Zhang,* and Weijing Yang* Cell Death Pathway Regulation by Functional Nanomedicines for Robust Antitumor Immunity, Advanced Science, 2023