职称：学科特聘教授、博士生导师
邮箱：wangyizd@zzu.edu.cn
地址：郑州大学天健生物医学实验室2号楼803室
学校学科特聘教授，河南省医学科技创新杰青人才。近年来致力于杂化生物材料的设计与生物医学应用研究。主持国家自然科学基金面上项目、青年项目与上海市自然科学基金项目、河南省医学科技创新项目等。共发表论文70余篇，其中第一/通讯作者（含共同）SCI论文65篇，包括 JACS、ACS Nano、Adv. Funct. Mater.、Nano Today、Nano Lett、Biomaterials等国际权威期刊。获授权发明专利16项，PCT申请1项。共同主编Springer Nature出版社的英文专著1部。获得教育部自然科学奖、上海药学科技奖、江苏医学科技奖等奖项。
近5年代表性论文：
1.Xu B, Luo J, Pang S, Tu C, Hu J, Zhao J, Zhang T, Guo P, Zheng W, Wang Y, Li W*, Wang Y*, Liu S*. Fluorinated Covalent Organic Framework Hydrogel Reprograms Piezo1/YAP Mechanotransduction for Sustained Prevention of Peritendinous Adhesion. Bioact. Mater. 2026, 68: 617-633.
2.Lv W, Jiang G, Lin X, Qian M, Huang R, Li Z, Liu H, Lin D, Wang Y*. An unusual application of multifunctional nanozyme derived from COF: augmenting chemoimmunotherapy while attenuating cardiotoxicity. Adv. Funct. Mater. 2025, 35:2412862.
3.e-camouflaged COF-based nanosatellite for enhanced tumor-targeted photothermal chemoimmunotherapy. Biomaterials 2025, 314:122869.
4.Yang L, Lv W, Wang Y, Wang Y*. Carbon nanotube incorporation and framework protonation-regulated energy band for enhanced photocatalytic hydrogen peroxide production of COF. Nano Res. 2025, 18:94907024.
5.Li J, Zhang M, Wang Y, Lv W, Xu Z, Wang B, Huang R, Mei B, Wang Y*. Regulating atomic active center by covalent organic framework-derived photothermal nanozyme to arm self-gelling powder for bacterial wound healing. ACS Nano 2024, 18:35606-35619.
6.Wu RP, Pang S, Lv WX, Zou J, Li YG, Li YH, He JB, Gu HY, Wang YT, Guan YY, Peng XC*, Wang Y*, Liu S*. Injectable pH-responsive CI1040 delayed-release hydrogel for the treatment of tendon adhesion. Adv. Funct. Mater. 2024, 34:2314731.
7.Lin XJ, Zhang M, Lv WX, Li J, Huang R, Wang Y*. Engineering carbon nanotube-based photoactive COF to synergistically arm a multifunctional antibacterial hydrogel. Adv. Funct. Mater. 2024, 34:2310845.
8.Nie DK, Ling YJ, Lv WX, Liu QQ, Deng S, Shi JL, Yang JL, Yang Yu Ouyang SG, Huang Y, Wang Y*, Huang RQ*, Shi W*. In situ attached photothermal immunomodulation-enhanced nanozyme for the inhibition of postoperative malignant glioma recurrence. ACS Nano 2023, 17(14):13885-13902.
9.Ling YJ#, Nie DK#, Huang Y#, Deng MY, Liu QQ, Shi JL, Ouyang SG, Yang Y, Deng S, Lu ZC, Yang JL, Wang Y*, Huang RQ*, Shi W*. Antioxidant cascade nanoenzyme antagonize inflammatory pain by modulating MAPK/p-65 signaling pathway. Adv. Sci. 2023, 10:2206934.
10.Deng MY, Zhang M, Huang R, Li HY, Lv WX, Lin XJ, Huang RQ*, Wang Y*. Diabetes immunity-modulated multifunctional hydrogel with cascade enzyme catalytic activity for bacterial wound treatment. Biomaterials 2022, 289:121790.
