个人简介

郑州大学学科骨干特聘教授，博士生导师，2003年获得学士学位，2010年获得华中农业大学生物化学与分子生物学博士学位，2010-2012在美国西北大学从事博士后研究，2012-2016任美国弗吉尼亚大学副研(Research Associate)，2016-2020年任美国弗吉尼亚大学研究科学家(Research Scientist)。先后获国家自然科学基金面上项目和NSFC-河南联合基金项目资助。

主要研究方向

主要从事前列腺癌和食管癌进展中的表观遗传调控；嵌合RNA的功能及分子机制研究；嵌合RNA在肿瘤发生发展中的功能和机制研究。

荣誉及获奖情况

2013年 Farrow Fellowship, UVa Cancer Center.

代表性成果：

#共同一作 *通讯作者

1. Chen, C.,# Qin, F.,# Singh, S., Tang, Y. and Li, H. (2023) CTNNBIP1-CLSTN1 functions as a housekeeping chimeric RNA and regulates cell proliferation through SERPINE2. Cell Death Discov, 9, 369.

2. Chen, C., Haddox, S., Tang, Y.,* Qin, F.* and Li, H. *(2021) Landscape of Chimeric RNAs in Non-Cancerous Cells. Genes (Basel), 12.

3. Singh, S., #Qin, F.,# Kumar, S., Elfman, J., Lin, E., Pham, L.P., Yang, A. and Li, H. (2020) The landscape of chimeric RNAs in non-diseased tissues and cells. Nucleic Acids Res, 48, 1764-1778.

4. Chwalenia, K.,# Qin, F.,# Singh, S. and Li, H. (2019) A cell-based splicing reporter system to identify regulators of cis-splicing between adjacent genes. Nucleic Acids Res, 47, e24.

5. Li, Z.,# Qin, F.# and Li, H. (2018) Chimeric RNAs and their implications in cancer. Curr Opin Genet Dev, 48, 36-43.

6. Qin, F., Zhang, Y., Liu, J. and Li, H. (2017) SLC45A3-ELK4 functions as a long non-coding chimeric RNA. Cancer Lett, 404, 53-61.

7. Qin, F., Song, Y., Zhang, Y., Facemire, L., Frierson, H. and Li, H. (2016) Role of CTCF in Regulating SLC45A3-ELK4 Chimeric RNA. PLoS One, 11, e0150382.

8. Qin, F., Song, Z., Chang, M., Song, Y., Frierson, H. and Li, H. (2016) Recurrent cis-SAGe chimeric RNA, D2HGDH-GAL3ST2, in prostate cancer. Cancer Lett, 380, 39-46.

9. Qin, F., Song, Z., Babiceanu, M., Song, Y., Facemire, L., Singh, R., Adli, M. and Li, H. (2015) Discovery of CTCF-sensitive Cis-spliced fusion RNAs between adjacent genes in human prostate cells. PLoS Genet, 11, e1005001.

10. Qin, F.J., Sun, Q.W., Huang, L.M., Chen, X.S. and Zhou, D.X. (2010) Rice SUVH histone methyltransferase genes display specific functions in chromatin modification and retrotransposon repression. Mol Plant, 3, 773-782.